Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Katja Suter"'
Autor:
Chiara Jeiziner, Ursina Wernli, Katja Suter, Kurt E. Hersberger, Henriette E. Meyer zu Schwabedissen
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 5, Pp 1648-1658 (2021)
Abstract Alleles of the human leukocyte antigen (HLA) system have been associated with the occurrence of idiosyncratic adverse drug reactions (ADRs). Accordingly, it is assumed that pre‐emptive testing for the presence of certain HLA alleles (HLA
Externí odkaz:
https://doaj.org/article/f5f8be4aacb246fbb5a32f1400cb50fb
Autor:
Henriette E. Meyer zu Schwabedissen, Chiara Jeiziner, Kurt E. Hersberger, Ursina Wernli, Katja Suter
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 5, Pp 1648-1658 (2021)
Clinical and Translational Science, Vol 14, Iss 5, Pp 1648-1658 (2021)
Alleles of the human leukocyte antigen (HLA) system have been associated with the occurrence of idiosyncratic adverse drug reactions (ADRs). Accordingly, it is assumed that pre‐emptive testing for the presence of certain HLA alleles (HLA‐typing)
Autor:
Teri E. Klein, Li Gong, Michelle Whirl-Carrillo, Chiara Jeiziner, Katja Suter, T D Szucs, H. E. Meyer zu Schwabedissen, Kurt E. Hersberger, U Wernli, Julia M. Barbarino
Publikováno v:
The Pharmacogenomics Journal
Implementation of pharmacogenetics (PGx) and individualization of drug therapy is supposed to obviate adverse drug reactions or therapy failure. Health care professionals (HCPs) use drug labels (DLs) as reliable information about drugs. We analyzed t
Autor:
Marlon Pflüger, Ronan Zimmermann, Jürgen Drewe, Peter Fuhr, Stephan Krähenbühl, Manuel Haschke, Stephan Rüegg, Martin Hardmeier, Massimiliano Donzelli, S. Deuster, Katja Suter
Publikováno v:
Clinical Pharmacology & Therapeutics. 91:856-862
The pharmacokinetics and pharmacodynamics of a highly concentrated cyclodextrin-based intranasal (i.n.) midazolam formulation containing the absorption-enhancer chitosan were studied in 12 healthy volunteers and compared with intravenous (i.v.) midaz
Autor:
Thomas Briellmann, Stephan Krähenbühl, Jürgen Drewe, Manuel Haschke, Katja Suter, Georgios Imanidis, Franz Dussy, Christian Surber, Sarah Hofmann, Johannes Fröhlich, Robert Witschi
Publikováno v:
British Journal of Clinical Pharmacology. 69:607-616
To investigate the pharmacokinetics and pharmacodynamics of nasal formulations containing midazolam (5-30 mg ml(-1)) complexed with cyclodextrin.; An open-label sequential trial was conducted in eight healthy subjects receiving single doses of 1 mg a
Autor:
Regina Kulier, Theodoros N. Arvanitis, Jacek Walzak, Julie Hadley, Tamás Decsi, Katja Suter, Khalid S. Khan, Regina Kunz, Amanda Burls, Andrea R. Horvath, Jose I. Emparanza, Gianni Zanrei, Sjors F.P.J. Coppus, Marcin Kaczor, Susanne Weinbrenner, Juan B. Cabello, Karin Pierer, Roland Schaffler, Ben W.J. Mol, Eva Nagy
Publikováno v:
Journal of Evaluation in Clinical Practice. 15:1196-1204
Background: Over the past decade, evidence-based medicine (EBM) has gained recognition as a means to improve the quality of health care provision. However, little is known about learning opportunities to acquire EBM-associated skills. The EUebm-Unity
Publikováno v:
Medizinische Monatsschrift fur Pharmazeuten. 38(2)
In addition to relative risk, relative risk reduction and absolute risk reduction there circulates another effect size for binary endpoints in the scientific medical literature: the odds ratio. Relative risk and odds ratio are alternative ways of ref
Publikováno v:
Medizinische Monatsschrift fur Pharmazeuten. 38(4)
In clinical trials data of individuals are collected, who are subjected to different treatments under controlled conditions. These studies investigate differences between interventions, and their results--provide the basis for clinical decision makin
Publikováno v:
Medizinische Monatsschrift fur Pharmazeuten. 38(3)
In our previous articles we introduced the relative and absolute expressions of risk: baseline risk, relative risk (RR), relative risk reduction (RRR), absolute risk reduction (ARR), or risk difference (RD). The "number needed to xy" is another conce
Publikováno v:
Medizinische Monatsschrift fur Pharmazeuten. 38(1)
Results of clinical trials are presented in different expressions of risks: baseline risk, relative risk (RR), relative risk reduction (RRR), absolute risk reduction (ARR), or risk difference (RD). In this article of our series about the basics of ev