Zobrazeno 1 - 10
of 501
pro vyhledávání: '"Katja Steiger"'
Autor:
Leonhard Stark, Atsuko Kasajima, Fabian Stögbauer, Benedikt Schmidl, Jakob Rinecker, Katharina Holzmann, Sarah Färber, Nicole Pfarr, Katja Steiger, Barbara Wollenberg, Jürgen Ruland, Christof Winter, Markus Wirth
Publikováno v:
Clinical Epigenetics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Background The unknown tissue of origin in head and neck cancer of unknown primary (hnCUP) leads to invasive diagnostic procedures and unspecific and potentially inefficient treatment options for patients. The most common histologic subtype,
Externí odkaz:
https://doaj.org/article/3924f13f9d754236b920773600a561fe
Autor:
Silvana Debernardi, Lukasz Liszka, Chara Ntala, Katja Steiger, Irene Esposito, Emanuela Carlotti, Ann‐Marie Baker, Stuart McDonald, Trevor Graham, Branko Dmitrovic, Roger M. Feakins, Tatjana Crnogorac‐Jurcevic
Publikováno v:
Molecular Oncology, Vol 18, Iss 3, Pp 677-690 (2024)
The median age of patients with pancreatic ductal adenocarcinoma (PDAC) at diagnosis is 71 years; however, around 10% present with early‐onset pancreatic cancer (EOPC), i.e., before age 50. The molecular mechanisms underlying such an early onset ar
Externí odkaz:
https://doaj.org/article/28e44b0fd78246999dcb6ae2e2fb819c
Autor:
Marie-Christin Weber, Konstantin Schmidt, Annalisa Buck, Atsuko Kasajima, Simon Becker, Chunqiao Li, Stefan Reischl, Dirk Wilhelm, Katja Steiger, Helmut Friess, Philipp-Alexander Neumann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Prevention of intestinal fibrosis remains an unresolved problem in the treatment of Crohn’s disease (CD), as specific antifibrotic therapies are not yet available. Appropriate analysis of fibrosis severity is essential for assessing the th
Externí odkaz:
https://doaj.org/article/4ca0ca5c0cdb4878a74e02cd07e72de9
Autor:
Sabrina Marcazzan, Marcos J. Braz Carvalho, Nghia T. Nguyen, Julia Strangmann, Julia Slotta-Huspenina, Anna Tenditnaya, Markus Tschurtschenthaler, Jonas Rieder, Andrea Proaño-Vasco, Vasilis Ntziachristos, Katja Steiger, Dimitris Gorpas, Michael Quante, Susanne Kossatz
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)
Abstract Background Esophageal cancer is one of the 10 most common cancers worldwide and its incidence is dramatically increasing. Despite some improvements, the current surveillance protocol with white light endoscopy and random untargeted biopsies
Externí odkaz:
https://doaj.org/article/ff6d310172284ca49bcfc681bab115a2
Autor:
Jia Rao, Marianne Sinn, Uwe Pelzer, Hanno Riess, Helmut Oettle, Ihsan E Demir, Helmut Friess, Carsten Jäger, Katja Steiger, Alexander Muckenhuber
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract Even after decades of research, pancreatic ductal adenocarcinoma (PDAC) remains a highly lethal disease and responses to conventional treatments remain mostly poor. Subclassification of PDAC into distinct biological subtypes has been propose
Externí odkaz:
https://doaj.org/article/ebc9a9694d4e4a05a5d62bac932a1b24
Autor:
Hui Wang, Marianne Remke, Thomas Horn, Kristina Schwamborn, Yiyao Chen, Katja Steiger, Wilko Weichert, Hans-Jürgen Wester, Margret Schottelius, Wolfgang A. Weber, Matthias Eiber
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background Targeting prostate-specific membrane antigen (PSMA) has been highly successful for imaging and treatment of prostate cancer. However, heterogeneity in immunohistochemistry indicates limitations in the effect of imaging and radionu
Externí odkaz:
https://doaj.org/article/e730479a683c4bf18070e7f31822ee14
Autor:
Luise Rupp, Ina Dietsche, Maximilian Kießler, Ulrich Sommer, Alexander Muckenhuber, Katja Steiger, Casper W. F. van Eijck, Leonard Richter, Rouzanna Istvanffy, Carsten Jäger, Helmut Friess, Casper H. J. van Eijck, Ihsan Ekin Demir, Carmen Mota Reyes, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages and associated with early distant metastasis and poor survival. Besides clinical factors, the tumor microenvironment (TME) emerged as a crucial determinant of patient s
Externí odkaz:
https://doaj.org/article/060c11c0f0df4fe48ce6b5de61634e0a
Autor:
Jinpeng Su, Zahra Harati Taji, Anna D. Kosinska, Edanur Ates Oz, Zhe Xie, Pavlo Bielytskyi, Mikhail Shein, Philipp Hagen, Shohreh Esmaeili, Katja Steiger, Ulrike Protzer, Anne K. Schütz
Publikováno v:
JHEP Reports, Vol 6, Iss 4, Pp 100997- (2024)
Background & Aims: Particulate hepatitis B core antigen (HBcoreAg) is a potent immunogen used as a vaccine carrier platform. HBcoreAg produced in E. coli encapsidates random bacterial RNA (bRNA). Using the heterologous protein-prime, viral-vector-boo
Externí odkaz:
https://doaj.org/article/f0879e7c303e4f3bbb4b61d82f789e2c
Autor:
Carolin Kitzberger, Khuram Shehzad, Volker Morath, Rebekka Spellerberg, Julius Ranke, Katja Steiger, Roland E. Kälin, Gabriele Multhoff, Matthias Eiber, Franz Schilling, Rainer Glass, Wolfgang A. Weber, Ernst Wagner, Peter J. Nelson, Christine Spitzweg
Publikováno v:
Molecular Therapy: Oncolytics, Vol 30, Iss , Pp 238-253 (2023)
New treatment strategies are urgently needed for glioblastoma (GBM)—a tumor resistant to standard-of-care treatment with a high risk of recurrence and extremely poor prognosis. Based on their intrinsic tumor tropism, adoptively applied mesenchymal
Externí odkaz:
https://doaj.org/article/d524b87cfd2b4c978c114bf543db85aa
Autor:
Martin Grashei, Pascal Wodtke, Jason G. Skinner, Sandra Sühnel, Nadine Setzer, Thomas Metzler, Sebastian Gulde, Mihyun Park, Daniela Witt, Hermine Mohr, Christian Hundshammer, Nicole Strittmatter, Natalia S. Pellegata, Katja Steiger, Franz Schilling
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract pH alterations are a hallmark of many pathologies including cancer and kidney disease. Here, we introduce [1,5-13C2]Z-OMPD as a hyperpolarized extracellular pH and perfusion sensor for MRI which allows to generate a multiparametric fingerpri
Externí odkaz:
https://doaj.org/article/e47e9472da1b44daad591e0e237537be