Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Katja S. Just"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Polypharmacy in older adults increases the risk of adverse drug reactions (ADRs), but studying this relationship is complex. In real-world data, the high number of medications, coupled with rare drug combinations, results in high-dimensional
Externí odkaz:
https://doaj.org/article/f415b8bfcd934a09afab2dbd305a85ab
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 161 (2024)
Background: The analysis of substrates of polymorphic cytochrome P450 (CYP) enzymes is important information to enable drug–drug interactions (DDIs) analysis and the relevance of pharmacogenetics in this context in large datasets. Our aim was to co
Externí odkaz:
https://doaj.org/article/a031389b7cb84d65b9d788a4da58d5f7
Publikováno v:
BMC Pharmacology and Toxicology, Vol 21, Iss 1, Pp 1-20 (2020)
Abstract Background Older adults are more prone to develop adverse drug reactions (ADRs) since they exhibit numerous risk factors. The first aim was to analyse the number of spontaneous ADR reports regarding older adults (> 65) in the ADR database of
Externí odkaz:
https://doaj.org/article/dcb0daab662b426d9cede6f7397e2e1c
Autor:
Immaculate M. Langmia, Katja S. Just, Sabrina Yamoune, Jürgen Brockmöller, Collen Masimirembwa, Julia C. Stingl
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Adverse drug reactions (ADRs) are one of the major causes of morbidity and mortality worldwide. It is well-known that individual genetic make-up is one of the causative factors of ADRs. Approximately 14 million single nucleotide polymorphisms (SNPs)
Externí odkaz:
https://doaj.org/article/6ea8d76ec19b495e8f188882fb9b788b
Autor:
Katja S. Just, Harald Dormann, Mathias Freitag, Marlen Schurig, Miriam Böhme, Michael Steffens, Catharina Scholl, Thomas Seufferlein, Ingo Graeff, Matthias Schwab, Julia C. Stingl
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Cytochrome P450 (CYP) 2D6 is a polymorphic enzyme expressed in the central nervous system (CNS), important in drug metabolism and with a potentially constitutive role in CNS function such as vigilance. This study aimed to analyze variability in CYP2D
Externí odkaz:
https://doaj.org/article/657a5919157248de9939a3c30aa4a8a9
Autor:
Katja S. Just, Judith Schmitt
Publikováno v:
Gynäkologische Endokrinologie. 21:101-106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::795f5b597e7e934d42c8e82366275920
https://doi.org/10.1007/s10304-022-00483-1
https://doi.org/10.1007/s10304-022-00483-1
Autor:
Katja S. Just, Catharina Scholl, Miriam Boehme, Kathrin Kastenmüller, Johannes M. Just, Markus Bleckwenn, Stefan Holdenrieder, Florian Meier, Klaus Weckbecker, Julia C. Stingl
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 1056 (2021)
The aim of this study was to compare effects of an individualized with a standardized risk assessment for adverse drug reactions to improve drug treatment with antithrombotic drugs in older adults. A randomized controlled trial was conducted in gener
Externí odkaz:
https://doaj.org/article/840e734802cc46e6bc9db50193174529
Publikováno v:
British journal of clinical pharmacology : BJCP 88(12), 5149-5165 (2022). doi:10.1111/bcp.15467 special issue: "Themed Issue: Methodological Consideration in Research and Development of Medicines for Children (C4C / Issue Edited by: Ian Wong, Saskia Dewildt"
British journal of clinical pharmacology : BJCP 88(12), 5149-5165 (2022). doi:10.1111/bcp.15467 special issue: "Themed Issue: Methodological Consideration in Research and Development of Medicines for Children (C4C / Issue Edited by: Ian Wong, Saskia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e63577df5680237f8b3bddf9785871
https://doi.org/10.1111/bcp.15467
https://doi.org/10.1111/bcp.15467
Publikováno v:
European journal of clinical pharmacology 79(2), 219-227 (2023). doi:10.1007/s00228-022-03433-9
European journal of clinical pharmacology, Ahead of
European journal of clinical pharmacology, Ahead of
European journal of clinical pharmacology 79(2), 219-227 (2023). doi:10.1007/s00228-022-03433-9
Published by Springer, New York
Published by Springer, New York
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73aece7e5f819482d9c17dfe74982a43
Autor:
Katja S Just
Publikováno v:
AINS - Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie. 56:652-665
Analysis of preoperative medication is used to assess the benefit and risk associated with continuing or discontinuing medication before and during surgery. Identifying adverse drug reactions and assessing its risks often leads to uncertainty. Typica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2631146af29d274060c94e84a51f3527
https://doi.org/10.1055/a-1226-4647
https://doi.org/10.1055/a-1226-4647