Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katja Pfafferot"'
Autor:
Megan K Murphy, Ling Yue, Ruimin Pan, Saikat Boliar, Anurag Sethi, Jianhui Tian, Katja Pfafferot, Etienne Karita, Susan A Allen, Emmanuel Cormier, Paul A Goepfert, Persephone Borrow, James E Robinson, S Gnanakaran, Eric Hunter, Xiang-Peng Kong, Cynthia A Derdeyn
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003173 (2013)
Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subset of HIV-1 infected subjects during chronic infection. Exact mechanisms that expand the otherwise narrow neutralization capacity observed during early
Externí odkaz:
https://doaj.org/article/1edc3710ec2d4edda9d5d3b09d3a1741
Autor:
Michaela Lucas, Axel Ulsenheimer, Katja Pfafferot, Malte H J Heeg, Silvana Gaudieri, Norbert Grüner, Andri Rauch, J Tilman Gerlach, Maria-Christina Jung, Reinhart Zachoval, Gerd R Pape, Winfried Schraut, Teresa Santantonio, Hans Nitschko, Martin Obermeier, Rodney Phillips, Thomas J Scriba, Nasser Semmo, Cheryl Day, Jonathan N Weber, Sarah Fidler, Robert Thimme, Anita Haberstroh, Thomas F Baumert, Paul Klenerman, Helmut M Diepolder
Publikováno v:
PLoS ONE, Vol 2, Iss 7, p e649 (2007)
CD4+ T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4+ T cell helper responses appear to be absent or short
Externí odkaz:
https://doaj.org/article/fe9de6f7104e48649f8ee0bdaf5db9c0
Autor:
Susan Allen, Megan K. Murphy, Saikat Boliar, Etienne Karita, James E. Robinson, Emmanuel Cormier, Sandrasegaram Gnanakaran, Ruimin Pan, Persephone Borrow, Eric Hunter, Anurag Sethi, Xiang-Peng Kong, Jianhui Tian, Katja Pfafferot, Paul A. Goepfert, Cynthia A. Derdeyn, Ling Yue
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003173 (2013)
PLoS Pathogens
PLoS Pathogens
Antibodies that neutralize (nAbs) genetically diverse HIV-1 strains have been recovered from a subset of HIV-1 infected subjects during chronic infection. Exact mechanisms that expand the otherwise narrow neutralization capacity observed during early
Autor:
Robert Thimme, Martin Obermeier, Teresa Santantonio, Gerd R. Pape, Helmut M. Diepolder, Katja Pfafferot, Michaela Lucas, Norbert H. Grüner, Axel Ulsenheimer, Reinhart Zachoval, Thomas J. Scriba, A. Haberstroh, Andri Rauch, Nasser Semmo, Paul Klenerman, Silvana Gaudieri, Malte H.J. Heeg, Hans Nitschko, Jonathan Weber, W. Schraut, Sarah Fidler, Thomas F. Baumert, Maria-Christina Jung, J. Tilman Gerlach, Rodney E. Phillips, Cheryl L. Day
Publikováno v:
PLoS ONE
PLoS ONE, Vol 2, Iss 7, p e649 (2007)
PLoS ONE, Vol 2, Iss 7, p e649 (2007)
Background. CD4 + T cell help is critical in maintaining antiviral immune responses and such help has been shown to be sustained in acute resolving hepatitis C. In contrast, in evolving chronic hepatitis C CD4 + T cell helper responses appear to be a
Autor:
Michaela Lucas, Pooja Deshpande, Ian James, Andri Rauch, Katja Pfafferott, Elouise Gaylard, Shahzma Merani, Anne Plauzolles, Andrew Lucas, Wyatt McDonnell, Spyros Kalams, Mark Pilkinton, Cody Chastain, Louise Barnett, Amy Prosser, Simon Mallal, Karen Fitzmaurice, Heidi Drummer, M. Azim Ansari, Vincent Pedergnana, Ellie Barnes, Mina John, Dermot Kelleher, Paul Klenerman, Silvana Gaudieri
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Hepatitis C virus (HCV)-specific T cell responses are critical for immune control of infection. Viral adaptation to these responses, via mutations within regions of the virus targeted by CD8+ T cells, is associated with viral persistence. Ho
Externí odkaz:
https://doaj.org/article/a3e921b0f5654281802b48dc72a509cb
Autor:
Katja Pfafferott, Pooja Deshpande, Elizabeth McKinnon, Shahzma Merani, Andrew Lucas, David Heckerman, Simon Mallal, Mina John, Silvana Gaudieri, Michaela Lucas
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130420 (2015)
Characterisation of Hepatitis C virus (HCV)-specific CD8+ T-cell responses in the context of multiple HCV exposures is critical to identify broadly protective immune responses necessary for an effective HCV vaccine against the different HCV genotypes
Externí odkaz:
https://doaj.org/article/beaef9146df446c3829409a68d4e5832
Autor:
Katja Pfafferott, Silvana Gaudieri, Axel Ulsenheimer, Ian James, Malte Heeg, David Nolan, Mina John, Andri Rauch, Simon Mallal, Andrew Lucas, Paul Klenerman, Helmut M Diepolder, Michaela Lucas
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e16797 (2011)
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune c
Externí odkaz:
https://doaj.org/article/82b1436b317041e584a3a3cefc152a36