Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Katja Nitschke"'
Autor:
Patrick Erwied, Yi Gu, Lena Simon, Martin Schneider, Dominic Helm, Maurice Stefan Michel, Philipp Nuhn, Katja Nitschke, Thomas Stefan Worst
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract To improve the prognosis of bladder and prostate cancer, highly specific and sensitive biomarkers are needed for early detection, prognosis prediction, and therapeutic stratification. Extracellular vesicles (EV) from plasma could fill this g
Externí odkaz:
https://doaj.org/article/1ca018edc380444b8d993689812d85bb
Autor:
Daniel Uysal, Blerta Thaqi, Alexander Fierek, David Jurgowski, Zoran V. Popovic, Fabian Siegel, Maurice Stephan Michel, Philipp Nuhn, Thomas Stefan Worst, Philipp Erben, Katja Nitschke
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionMuscle invasive bladder cancer (MIBC) remains a prevalent cancer with limited therapeutic options, obviating the need for innovative therapies. The epidermal growth factor receptor (EGFR) is a linchpin in tumor progression and presents a
Externí odkaz:
https://doaj.org/article/f99abe57e02c45058530681e62a58470
Autor:
Luisa Tengler, Moritz Tiedtke, Julia Schütz, Karen Bieback, Stefanie Uhlig, Marie-Nicole Theodoraki, Katja Nitschke, Thomas Stefan Worst, Elena Seiz, Claudia Scherl, Nicole Rotter, Sonja Ludwig
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Small extracellular vesicles from saliva (SEVs) have high potential as biomarkers in Head and Neck cancer (HNC). However, there is no common consensus on the ideal method for their isolation. This study compared different ultracentrifugation
Externí odkaz:
https://doaj.org/article/85dae743409c4b7ab7ae3db9fd7f4118
Autor:
Luisa Tengler, Julia Schütz, Moritz Tiedtke, Jadwiga Jablonska, Marie-Nicole Theodoraki, Katja Nitschke, Christel Weiß, Elena Seiz, Annette Affolter, Frederic Jungbauer, Anne Lammert, Nicole Rotter, Sonja Ludwig
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-14 (2023)
Abstract Background In Head and neck cancer (HNC) angiogenesis is essential for tumor progression and metastasis. Small extracellular vesicles (sEVs) from HNC cell lines alter endothelial cell (EC) functions towards a pro-angiogenic phenotype. Howeve
Externí odkaz:
https://doaj.org/article/3c4c110c4b2d42b5ad0d78327d26b01c
Autor:
Manuel Neuberger, Christel Weiß, Nora Goly, Janina Skladny, Katja Nitschke, Frederik Wessels, Karl F. Kowalewski, Frank Waldbillig, Friedrich Hartung, Malin Nientiedt, Luisa Egen, Jonas Herrmann, Jonas Jarczyk, Margarete Teresa Walach, Maximilian C. Kriegmair, Niklas Westhoff, Thomas S. Worst, Philipp Nuhn
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Objectives To assess the predictive and prognostic value of changes in longitudinal neutrophile-to-lymphocyte (NLR) ratios in men receiving taxane-based chemotherapy for metastatic prostate cancer (PC). Methods Retrospective, unicentric coho
Externí odkaz:
https://doaj.org/article/ac13e6972f414f87831c525004e94f2a
Autor:
Hui Li, Annette Breedijk, Nadine Dietrich, Katja Nitschke, Jonas Jarczyk, Philipp Nuhn, Bernhard K. Krämer, Benito A. Yard, Jan Leipe, Sibylle Hauske
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12196 (2023)
Innate immune memory allows macrophages to adequately respond to pathogens to which they have been pre-exposed. To what extent different pattern recognition receptors, cytokines and resolution signals influence innate immune memory needs further eluc
Externí odkaz:
https://doaj.org/article/c0caf95a18d04e47a392a7e62103c906
Autor:
Sheng Wu, Katja Nitschke, Thomas Stefan Worst, Alexander Fierek, Cleo-Aron Weis, Markus Eckstein, Stefan Porubsky, Maximilian Kriegmair, Philipp Erben
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Growing evidence supports the pivotal role of long non-coding RNAs (lncRNAs) in the regulation of cancer development and progression. Their expression patterns and biological function in muscle invasive bladder cancer (MIBC) remai
Externí odkaz:
https://doaj.org/article/4588d72d81bb4f42b76a4ba2beb76f94
Autor:
Sara Alameldin, Victor Costina, Hesham A. Abdel-Baset, Katja Nitschke, Phillip Nuhn, Michael Neumaier, Maren Hedtke
Publikováno v:
Practical Laboratory Medicine, Vol 26, Iss , Pp e00241- (2021)
Objectives: Exosomes are small lipid bilayer vesicles that are defined by their endocytic origin and size range of 30–140 nm. They are constantly produced by different cell types, by both healthy and abnormal cells, and can be isolated from almost
Externí odkaz:
https://doaj.org/article/a5b387219d70429e891e59dd6fbfb373
Autor:
Xuehui Fan, Lukas Cyganek, Katja Nitschke, Stefanie Uhlig, Philipp Nuhn, Karen Bieback, Daniel Duerschmied, Ibrahim El-Battrawy, Xiaobo Zhou, Ibrahim Akin
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8507 (2022)
Endothelial cells derived from human induced pluripotent stem cells (hiPSC-ECs) provide a new opportunity for mechanistic research on vascular regeneration and drug screening. However, functions of hiPSC-ECs still need to be characterized. The object
Externí odkaz:
https://doaj.org/article/bd151b45956f4fca8294937c83244415
Autor:
Jonas Herrmann, Helena Schmidt, Katja Nitschke, Cleo-Aron Weis, Philipp Nuhn, Jost von Hardenberg, Maurice Stephan Michel, Philipp Erben, Thomas Stefan Worst
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 8, p 4188 (2021)
Background: Perioperative cisplatin-based chemotherapy (CBC) can improve the outcome of patients with muscle-invasive bladder cancer (MIBC), but it is still to be defined which patients benefit. Mutations in DNA damage response genes (DDRG) can predi
Externí odkaz:
https://doaj.org/article/3e35ea80479d4a4c9ba14362abc2813b