Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katja Nieweg"'
Autor:
Kim N Pielarski, Bernd van Stegen, Aksana Andreyeva, Katja Nieweg, Kay Jüngling, Christoph Redies, Kurt Gottmann
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54105 (2013)
Synapse elimination and pruning of axon collaterals are crucial developmental events in the refinement of neuronal circuits. While a control of synapse formation by adhesion molecules is well established, the involvement of adhesion molecules in deve
Externí odkaz:
https://doaj.org/article/6066c9f0b14b48b0a23082510a50c628
Publikováno v:
Glia. 67:1893-1909
Human astrocytes differ dramatically in cell morphology and gene expression from murine astrocytes. The latter are well known to be of major importance in the formation of neuronal networks by promoting synapse maturation. However, whether human astr
Publikováno v:
Biological chemistryReferences. 400(9)
Historically considered as accessory cells to neurons, there is an increasing interest in the role of astrocytes in normal and pathological conditions. Astrocytes are involved in neurotransmitter recycling, antioxidant supply, ion buffering and neuro
Autor:
Kurt Gottmann, Katja Nieweg, Nicole Brockmann, Gerhard Fritz, Matthias U. Kassack, Tatiana Hennicke
Publikováno v:
Toxicological Sciences. 144:138-150
Because of high exposure to systemic noxae, vascular endothelial cells (EC) have to ensure distinct damage defense and regenerative mechanisms to guarantee vascular health. For meaningful toxicological drug assessments employing embryonic stem cell (
Autor:
Birgit Honrath, Braxton Norwood, Gaye Tanrioever, Katarzyna Kuter, Henshall, David C., Ayla Aksel-Aksoy, Gerhard Schratt, Jeroen Pasterkamp, Dencher, Norbert A., Katja Nieweg, Carsten Culmsee, Amalia Dolga
Publikováno v:
8th Annual Alliance for Healthy Aging Conference
University of Groningen
University of Groningen
Background Excessive and hypersynchronous neuronal discharges are key characteristics in the pathophysiology of neurological disorders such as epilepsy. Owing to their ability of regulating neuronal excitability, small conductance calcium-activated p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::10e59d612a356b2537b7079693b64379
https://research.rug.nl/en/publications/9991f96f-1495-4768-b7b6-e7950254d005
https://research.rug.nl/en/publications/9991f96f-1495-4768-b7b6-e7950254d005
Publikováno v:
Journal of Neurochemistry
Journal of Neurochemistry, Wiley, 2009, 109, pp.125-134
Journal of Neurochemistry, Wiley, 2009, 109 (1), pp.125-134. ⟨10.1111/j.1471-4159.2009.05917.x⟩
Journal of Neurochemistry, Wiley, 2009, 109, pp.125-134
Journal of Neurochemistry, Wiley, 2009, 109 (1), pp.125-134. ⟨10.1111/j.1471-4159.2009.05917.x⟩
Neurons have a high demand for cholesterol to develop and maintain membrane-rich structures like axons, dendrites and synapses, but it remains unclear, whether they can satisfy their need by costly de novo synthesis. To address this, we compared chol
Autor:
Katja Nieweg, Renaud Thiebaut, Leon J. Schurgers, Christoph Moehle, Frank W. Pfrieger, Gerd Schmitz, Christian Göritz, Luc-Henri Tessier, Jean-Luc Dupont, Isabelle Buard
Publikováno v:
Glia
Glia, Wiley, 2007, 55 (11), pp.1108-1122. ⟨10.1002/glia.20531⟩
Glia, Wiley, 2007, 55 (11), pp.1108-1122. ⟨10.1002/glia.20531⟩
There is increasing evidence that different phases of brain development depend on neuron-glia interactions including postnatal key events like synaptogenesis. To address how glial cells influence synapse development, we analyzed whether and how glia-
Autor:
Bernd van Stegen, Aksana Andreyeva, Katja Nieweg, Kurt Gottmann, Christoph Redies, Kay Jüngling, Kim N. Pielarski
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e54105 (2013)
PLoS ONE, Vol 8, Iss 1, p e54105 (2013)
Synapse elimination and pruning of axon collaterals are crucial developmental events in the refinement of neuronal circuits. While a control of synapse formation by adhesion molecules is well established, the involvement of adhesion molecules in deve
Autor:
Petra Lichtenecker, Beat Lutz, Julia Leschik, Katja Nieweg, Tanja Brigadski, Volkmar Lessmann, Kurt Gottmann, Robert Eckenstaler
Publikováno v:
Journal of Cell Science.
Brain-derived neurotrophic factor (BDNF) is known to be a crucial regulator of neuronal survival and synaptic plasticity in the mammalian brain. Furthermore, BDNF positively influences differentiation of embryonic neural precursors as well as of neur
Autor:
Katja Nieweg, Carsten Korth, Kurt Gottmann, Aksana Andreyeva, Simon D. Klapper, Katharina Horstmann, Andreas Müller-Schiffmann
Publikováno v:
Brain
The aetiology of Alzheimer's disease is thought to include functional impairment of synapses and synapse loss as crucial pathological events leading to cognitive dysfunction and memory loss. Oligomeric amyloid-β peptides are well known to induce fun