Metabolite Profiling in Arabidopsisthaliana with Moderately Impaired Photorespiration Reveals Novel Metabolic Links and Compensatory Mechanisms of Photorespiration

Autor: Stefan Timm, Adriano Nunes-Nesi, Alexandra Florian, Marion Eisenhut, Katja Morgenthal, Markus Wirtz, Rüdiger Hell, Wolfram Weckwerth, Martin Hagemann, Alisdair R. Fernie, Hermann Bauwe

Publikováno v: Metabolites, Vol 11, Iss 6, p 391 (2021)

Photorespiration is an integral component of plant primary metabolism. Accordingly, it has been often observed that impairing the photorespiratory flux negatively impacts other cellular processes. In this study, the metabolic acclimation of the Arabi

Externí odkaz: https://doaj.org/article/63ce8d3011774637b5a56e572c318c0c

Metabolomic networks in plants: Transitions from pattern recognition to biological interpretation

Autor: Katja Morgenthal, Wolfram Weckwerth, Ralf Steuer

Publikováno v: Biosystems. 83:108-117

Nowadays techniques for non-targeted metabolite profiling allow for the generation of huge amounts of relevant data essential for the construction of dynamic metabolomic networks. Thus, metabolomics, besides transcriptomics or proteomics, provides a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cd79091afc91bae6679d4d97be611e
https://doi.org/10.1016/j.biosystems.2005.05.017

First Steps Towards an Understanding of a Mode of Carcinogenic Action for Vanadium Pentoxide

Autor: Detlef Schuler, Marc Walter, Jean-Luc Ravanat, Hans-Jörg Chevalier, Katja Morgenthal, Klaus Weber, Peter Sagelsdorff, Douglas McGregor, Mandy Merker

Publikováno v: Journal of Toxicologic Pathology
Journal of Toxicologic Pathology, 2011, 24 (3), pp.149-162. ⟨10.1293/Tox.24.149⟩
Journal of Toxicologic Pathology, Japanese Society of Toxicologic Pathology, 2011, 24 (3), pp.149-162. ⟨10.1293/Tox.24.149⟩

Inhalation of vanadium pentoxide clearly increases the incidence of alveolar/bronchiolar neoplasms in male and female B6C3F1 mice at all concentrations tested (1, 2 or 4 mg/m(3)), whereas responses in F344/N rats was, at most, ambiguous. While vanadi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8329e934da62415191de4d03fe62c0b9
https://hal.science/hal-03390382

Deletion of glycine decarboxylase in arabidopsis is lethal under nonphotorespiratory conditions

Autor: Nadja Engel, Olav Keerberg, Tiit Pärnik, Hermann Bauwe, Kirsten van den Daele, Üner Kolukisaoglu, Katja Morgenthal, Wolfram Weckwerth

Publikováno v: Plant Physiology

The mitochondrial multienzyme glycine decarboxylase (GDC) catalyzes the tetrahydrofolate-dependent catabolism of glycine to 5,10-methylene-tetrahydrofolate and the side products NADH, CO2, and NH3. This reaction forms part of the photorespiratory cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d90ce8786e8417f6b8b3653f7da880f
https://hdl.handle.net/11858/00-001M-0000-0014-2943-B11858/00-001M-0000-0014-2941-F

A Gentle Guide to the Analysis of Metabolomic Data

Autor: Katja Morgenthal, Wolfram Weckwerth, Joachim Selbig, Ralf Steuer

Publikováno v: Metabolomics ISBN: 9781588295613

Modern molecular biology crucially relies on computational tools to handle and interpret the large amounts of data that are generated by high-throughput measurements. To this end, much effort is dedicated to devise novel sophisticated methods that al

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07d4788d3969f26399369db6f7c41b3
https://doi.org/10.1007/978-1-59745-244-1_7