Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Katja M Kanninen"'
Autor:
Shenpan Li, Shuangjian Qin, Huixian Zeng, Weichun Chou, Anna Oudin, Katja M. Kanninen, Pasi Jalava, Guanghui Dong, Xiaowen Zeng
Publikováno v:
Eco-Environment & Health, Vol 3, Iss 4, Pp 476-493 (2024)
Per- and polyfluoroalkyl substances (PFAS) are endocrine disruptors with unambiguous neurotoxic effects. However, due to variability in experimental models, population characteristics, and molecular endpoints, the elucidation of mechanisms underlying
Externí odkaz:
https://doaj.org/article/15707254f7a4459d81c2c0658031890d
Autor:
Gabin Drouard, Zhiyang Wang, Aino Heikkinen, Maria Foraster, Jordi Julvez, Katja M. Kanninen, Irene van Kamp, Matti Pirinen, Miina Ollikainen, Jaakko Kaprio
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Whether differences in lifestyle between co-twins are reflected in differences in their internal or external exposome profiles remains largely underexplored. We therefore investigated whether within-pair differences in lifestyle were associa
Externí odkaz:
https://doaj.org/article/0a76e6177f3c42b88f40bdd76d1f58ad
Autor:
Anna Oudin, Wasif Raza, Erin Flanagan, David Segersson, Pasi Jalava, Katja M. Kanninen, Topi Rönkkö, Rosalba Giugno, Thomas Sandström, Ala Muala, Jan Topinka, Johan Sommar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The aim of this study was to investigate the relationship between source-specific ambient particulate air pollution concentrations and the incidence of dementia. The study encompassed 70,057 participants from the Västerbotten intervention p
Externí odkaz:
https://doaj.org/article/dc18f44324f04a1c8f2fea57a4c1a39b
Autor:
Laura Mussalo, Riikka Lampinen, Simone Avesani, Táňa Závodná, Zdeněk Krejčík, Juho Kalapudas, Elina Penttilä, Heikki Löppönen, Anne M. Koivisto, Tarja Malm, Jan Topinka, Rosalba Giugno, Pasi Jalava, Katja M. Kanninen
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103272- (2024)
Constituents of air pollution, the ultrafine particles (UFP) with a diameter of ≤0.1 μm, are considerably related to traffic emissions. Several studies link air pollution to Alzheimer's disease (AD), yet the exact relationship between the two rema
Externí odkaz:
https://doaj.org/article/5fe4cf95d0a6478bb39e07f3433e085c
Autor:
Wasif Raza, Anders Öhman, Katja M. Kanninen, Pasi Jalava, Xiao-wen Zeng, Tosca O. E. de Crom, M. Arfan Ikram, Anna Oudin
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionAir pollution is a significant contributor to morbidity and mortality globally and has been linked to an increased risk of dementia. Previous studies within the Betula cohort in Northern Sweden have demonstrated associations between air p
Externí odkaz:
https://doaj.org/article/08d17fab718d4e879d742a9ec061547e
Autor:
Henna Jäntti, Steffi Jonk, Mireia Gómez Budia, Sohvi Ohtonen, Ilkka Fagerlund, Mohammad Feroze Fazaludeen, Päivi Aakko-Saksa, Alice Pebay, Šárka Lehtonen, Jari Koistinaho, Katja M. Kanninen, Pasi I. Jalava, Tarja Malm, Paula Korhonen
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background Air pollution is recognized as an emerging environmental risk factor for neurological diseases. Large-scale epidemiological studies associate traffic-related particulate matter (PM) with impaired cognitive functions and increased
Externí odkaz:
https://doaj.org/article/2ffcedbcf3f049898ce5fdfb9dd94b96
Autor:
Alexey M. Afonin, Aino-Kaisa Piironen, Izaque de Sousa Maciel, Mariia Ivanova, Arto Alatalo, Alyce M. Whipp, Lea Pulkkinen, Richard J. Rose, Irene van Kamp, Jaakko Kaprio, Katja M. Kanninen
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Global emphasis on enhancing prevention and treatment strategies necessitates an increased understanding of the biological mechanisms of psychopathology. Plasma proteomics is a powerful tool that has been applied in the context of specific m
Externí odkaz:
https://doaj.org/article/a88e986008444d5bb8e003bbedfe5976
Autor:
Diane Moujalled, Janine L James, Sarah J Parker, Grace E Lidgerwood, Clare Duncan, Jodi Meyerowitz, Takashi Nonaka, Masato Hasegawa, Katja M Kanninen, Alexandra Grubman, Jeffrey R Liddell, Peter J Crouch, Anthony R White
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67433 (2013)
Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD). It is unclear how changes to TDP-43, inc
Externí odkaz:
https://doaj.org/article/822af7482111429990e59008df89fd00
Autor:
Katja M Kanninen, Alexandra Grubman, Jodi Meyerowitz, Clare Duncan, Jiang-Li Tan, Sarah J Parker, Peter J Crouch, Brett M Paterson, James L Hickey, Paul S Donnelly, Irene Volitakis, Imke Tammen, David N Palmer, Anthony R White
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58644 (2013)
Mutations in the CLN6 gene cause a variant late infantile form of neuronal ceroid lipofuscinosis (NCL; Batten disease). CLN6 loss leads to disease clinically characterized by vision impairment, motor and cognitive dysfunction, and seizures. Accumulat
Externí odkaz:
https://doaj.org/article/ab28937cb16247ea8602d2fcbf29fd16
Autor:
Sarah J Parker, Jodi Meyerowitz, Janine L James, Jeffrey R Liddell, Takashi Nonaka, Masato Hasegawa, Katja M Kanninen, SinChun Lim, Brett M Paterson, Paul S Donnelly, Peter J Crouch, Anthony R White
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42277 (2012)
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, motor neuron disease with no effective long-term treatment options. Recently, TDP-43 has been identified as a key protein in the pathogenesis of some cases of ALS. Although the role of TDP-
Externí odkaz:
https://doaj.org/article/3b5512010cb641b9b53449d57880b60f