Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography for Imaging Tumor Progression and Early Response in Non-Small Cell Lung Cancer

Autor: Xiaopeng Ma, Valerie Phi Van, Melanie A. Kimm, Jaya Prakash, Horst Kessler, Katja Kosanke, Annette Feuchtinger, Michaela Aichler, Aayush Gupta, Ernst J. Rummeny, Michel Eisenblätter, Jens Siveke, Axel K. Walch, Rickmer Braren, Vasilis Ntziachristos, Moritz Wildgruber

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 1, Pp 8-16 (2017)

Integrins play an important role in tumor progression, invasion and metastasis. Therefore we aimed to evaluate a preclinical imaging approach applying ανβ3 integrin targeted hybrid Fluorescence Molecular Tomography/X-ray Computed Tomography (FMT-X

Externí odkaz: https://doaj.org/article/cca4c019ff4249e8a2046ea0dbf7d60d

Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles.

Autor: Marcus Settles, Martin Etzrodt, Katja Kosanke, Matthias Schiemann, Alexander Zimmermann, Reinhard Meier, Rickmer Braren, Armin Huber, Ernst J Rummeny, Ralph Weissleder, Filip K Swirski, Moritz Wildgruber

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e25197 (2011)

To explore the capacity of human CD1⁺CD16⁺⁺ and CD14⁺⁺CD16⁻ monocytes to phagocyte iron-oxide nanoparticles in vitro.Human monocytes were labeled with four different magnetic nanoparticle preparations (Ferumoxides, SHU 555C, CLIO-680, MIO

Externí odkaz: https://doaj.org/article/995b93910ac944a780094f58d27e9282

Characterization of Cardiac Dynamics in an Acute Myocardial Infarction Model by Four-Dimensional Optoacoustic and Magnetic Resonance Imaging

Autor: Xosé Luís Deán-Ben, Hsiao-Chun Amy Lin, Daniel Razansky, Melanie A. Kimm, Katja Kosanke, Helena Haas, Moritz Wildgruber, Reinhard Meier, Fabian Lohöfer, Ivana Ivankovic

Publikováno v: Theranostics
Theranostics 7, 4470-4479 (2017)

Extraction of murine cardiac functional parameters on a beat-by-beat basis is limited with the existing imaging modalities due to insufficient three-dimensional temporal resolution. Faster volumetric imaging methods enabling in vivo characterization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bb7e9b4c47dcd14c602b7f9526099c8
https://mediatum.ub.tum.de/doc/1441817/document.pdf

Multispectral optoacoustic tomography of myocardial infarction

Autor: Vasilis Ntziachristos, Nicolas Beziere, Axel Walch, Katja Kosanke, Michaela Aichler, Rainer Haag, Ernst J. Rummeny, Moritz Wildgruber, Adrian Taruttis, Kai Licha

Publikováno v: Photoacoustics
Photoacoustics 1, 3-8 (2013)

Highlights ► Multispectral optoacoustics enables in vivo preclinical imaging of heart infarct. ► The spatial resolution is superior to previous deep-tissue optical techniques. ► Molecular contrast is provided by an exogenous inflammation-target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46ebaeb44aadc1fb665ff5b017b1bd0
https://doi.org/10.1016/j.pacs.2012.11.001

Molecular imaging of myocardial infarction with Gadofluorine P – A combined magnetic resonance and mass spectrometry imaging approach

Autor: Katharina Huber, Fabian Lohöfer, Katja Kosanke, Rebecca Buchholz, Uwe Karst, Axel Walch, Georgios Kaissis, Annette Feuchtinger, Almut Glinzer, Franz Schilling, Laura Hoffmann, Ernst J. Rummeny, Michaela Aichler, Benedikt Feuerecker, Carsten Höltke, Cornelius Faber, Moritz Wildgruber, René M. Botnar

Publikováno v: Heliyon, Vol 4, Iss 4, Pp e00606-(2018)
Lohöfer, F, Hoffmann, L, Buchholz, R, Huber, K, Glinzer, A, Kosanke, K, Feuchtinger, A, Aichler, M, Feuerecker, B, Kaissis, G, Rummeny, E J, Höltke, C, Faber, C, Schilling, F, Botnar, R M, Walch, A K, Karst, U & Wildgruber, M 2018, ' Molecular imaging of myocardial infarction with Gadofluorine P : A combined magnetic resonance and mass spectrometry imaging approach ', Heliyon, vol. 4, no. 4, pp. e00606 . https://doi.org/10.1016/j.heliyon.2018.e00606
Heliyon
Heliyon 4:e00606 (2018)

Background Molecular MRI is becoming increasingly important for preclinical research. Validation of targeted gadolinium probes in tissue however has been cumbersome up to now. Novel methodology to assess gadolinium distribution in tissue after in viv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dac9d58c3ee074710c65e7b5201d3a9
https://doi.org/10.1016/j.heliyon.2018.e00606