Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Katja Handschick"'
Autor:
Liane Jurida, Johanna Soelch, Marek Bartkuhn, Katja Handschick, Helmut Müller, Doris Newel, Axel Weber, Oliver Dittrich-Breiholz, Heike Schneider, Sabin Bhuju, Vera V. Saul, M. Lienhard Schmitz, Michael Kracht
Publikováno v:
Cell Reports, Vol 10, Iss 5, Pp 726-739 (2015)
The inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled NF-κB
Externí odkaz:
https://doaj.org/article/bbf478becfda4bdf955b0f7f60798020
Autor:
Holger Buss, Katja Handschick, Nadine Jurrmann, Pirita Pekkonen, Knut Beuerlein, Helmut Müller, Robin Wait, Jeremy Saklatvala, Päivi M Ojala, M Lienhard Schmitz, Michael Naumann, Michael Kracht
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51847 (2012)
Nuclear factor kappa-B (NF-κB) activates multiple genes with overlapping roles in cell proliferation, inflammation and cancer. Using an unbiased approach we identified human CDK6 as a novel kinase phosphorylating NF-κB p65 at serine 536. Purified a
Externí odkaz:
https://doaj.org/article/f0f07af112614169b2d732e1310cee77
Autor:
Maren Scharfe, Michael Kracht, Liane Jurida, Knut Beuerlein, Katja Handschick, M. Lienhard Schmitz, Julia Stellzig, Michael Jarek, Marek Bartkuhn, Oliver Dittrich-Breiholz, Axel Weber, Johanna Soelch, Helmut Müller, Heike Schneider
Publikováno v:
Molecular cell. 53(2)
Given the intimate link between inflammation and dysregulated cell proliferation in cancer, we investigated cytokine-triggered gene expression in different cell cycle stages. Transcriptome analysis revealed that G1 release through cyclin-dependent ki
Autor:
Oliver Dittrich-Breiholz, Johanna Soelch, Heike Schneider, Vera V. Saul, Katja Handschick, M. Lienhard Schmitz, Helmut Müller, Liane Jurida, Doris Newel, Michael Kracht, Sabin Bhuju, Axel Weber, Marek Bartkuhn
Publikováno v:
Cell Reports, Vol 10, Iss 5, Pp 726-739 (2015)
SummaryThe inflammatory gene response requires activation of the protein kinase TAK1, but it is currently unknown how TAK1-derived signals coordinate transcriptional programs in the genome. We determined the genome-wide binding of the TAK1-controlled