Zobrazeno 1 - 2
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pro vyhledávání: '"Katja Glinšek"'
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8144 (2023)
The Chinese hamster ovary (CHO) cell line is a well-established platform for the production of biopharmaceuticals due to its ability to express complex therapeutic proteins with human-like glycopatterns in high amounts. The advent of CRISPR technolog
Externí odkaz:
https://doaj.org/article/6cc4637829b94771a52c4a75d0c7cab5
Autor:
Katja, Glinšek, Lovro, Kramer, Aleksander, Krajnc, Eva, Kranjc, Nina, Pirher, Jaka, Marušič, Leon, Hellmann, Barbara, Podobnik, Borut, Štrukelj, David, Ausländer, Rok, Gaber
Publikováno v:
Biotechnology Journal. 17:2100499
Difficulties in obtaining and maintaining the desired level of the critical quality attributes (CQAs) of therapeutic proteins as well as the pace of the development are major challenges of current biopharmaceutical development. Therapeutic proteins,