Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Katja Gemperlein"'
Autor:
Katja Gemperlein, Demian Dietrich, Michael Kohlstedt, Gregor Zipf, Hubert S. Bernauer, Christoph Wittmann, Silke C. Wenzel, Rolf Müller
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Sustainable sources are needed to meet the demand for long-chain polyunsaturated fatty acids. Here the authors construct an artificial biosynthetic gene cluster in Y. lipolytica capable of producing a high concentration of PUFAs.
Externí odkaz:
https://doaj.org/article/ace1af233c2740f59272853e227a43e3
Autor:
Tarek Kröhler, Sonja M. Kessler, Kevan Hosseini, Markus List, Ahmad Barghash, Sonika Patial, Stephan Laggai, Katja Gemperlein, Johannes Haybaeck, Rolf Müller, Volkhard Helms, Marcel H. Schulz, Jessica Hoppstädter, Perry J. Blackshear, Alexandra K. Kiemer
Publikováno v:
Cancers, Vol 11, Iss 11, p 1754 (2019)
Hepatic lipid deposition and inflammation represent risk factors for hepatocellular carcinoma (HCC). The mRNA-binding protein tristetraprolin (TTP, gene name ZFP36) has been suggested as a tumor suppressor in several malignancies, but it increases in
Externí odkaz:
https://doaj.org/article/8c1826025d7d4e1a9411e6f70837388a
Autor:
Stephan Laggai, Sonja M. Kessler, Stefan Boettcher, Valérie Lebrun, Katja Gemperlein, Eva Lederer, Isabelle A. Leclercq, Rolf Mueller, Rolf W. Hartmann, Johannes Haybaeck, Alexandra K. Kiemer
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 6, Pp 1087-1097 (2014)
Liver-specific overexpression of the insulin-like growth factor 2 (IGF2) mRNA binding protein p62/IGF2BP2-2 induces a fatty liver, which highly expresses IGF2. Because IGF2 expression is elevated in patients with steatohepatitis, the aim of our study
Externí odkaz:
https://doaj.org/article/0283ff4865f744bf9a3cfc33e5226500
Autor:
Sonja M. Kessler, Yvette Simon, Katja Gemperlein, Kathrin Gianmoena, Cristina Cadenas, Vincent Zimmer, Juliane Pokorny, Ahmad Barghash, Volkhard Helms, Nico van Rooijen, Rainer M. Bohle, Frank Lammert, Jan G. Hengstler, Rolf Mueller, Johannes Haybaeck, Alexandra K. Kiemer
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5762-5773 (2014)
Non-alcoholic steatohepatitis (NASH) represents a risk factor for the development of hepatocellular carcinoma (HCC) and is characterized by quantitative and qualitative changes in hepatic lipids. Since elongation of fatty acids from C16 to C18 has re
Externí odkaz:
https://doaj.org/article/eead95e827204c9c839e6b1f5290d59a
Autor:
Sonja M Kessler, Stephan Laggai, Elien Van Wonterghem, Katja Gemperlein, Rolf Müller, Johannes Haybaeck, Roosmarijn E. Vandenbroucke, Manfred Ogris, Claude Libert, Alexandra Kathrin Kiemer
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Externí odkaz:
https://doaj.org/article/613cb79fbeb04a7eaa13250fcec72d09
Publikováno v:
Marine Drugs, Vol 16, Iss 9, p 314 (2018)
Prior to 2005, the vast majority of characterized myxobacteria were obtained from terrestrial habitats. Since then, several species of halotolerant and even obligate marine myxobacteria have been described. Chemical analyses of extracts from these or
Externí odkaz:
https://doaj.org/article/a1dad83643404e298239e164d2daa338
Autor:
Kathrin Gianmoena, Juliane Pokorny, Frank Lammert, Sonja M. Kessler, Rolf Mueller, Yvette Simon, Johannes Haybaeck, Katja Gemperlein, Cristina Cadenas, Volkhard Helms, Rainer M. Bohle, Ahmad Barghash, Vincent Zimmer, Jan G. Hengstler, Alexandra K. Kiemer, Nico van Rooijen
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 4, Pp 5762-5773 (2014)
International Journal of Molecular Sciences; Volume 15; Issue 4; Pages: 5762-5773
International Journal of Molecular Sciences, 15(4), 5762-5773. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Kessler, S M, Simon, Y, Gemperlein, K, Gianmoena, K, Cadenas, C, Zimmer, V, Pokorny, J, Barghash, A, Helms, V, van Rooijen, N, Bohle, R M, Lammert, F, Hengstler, J G, Mueller, R, Haybaeck, J & Kiemer, A K 2014, ' Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma ', International Journal of Molecular Sciences, vol. 15, no. 4, pp. 5762-5773 . https://doi.org/10.3390/ijms15045762
International Journal of Molecular Sciences; Volume 15; Issue 4; Pages: 5762-5773
International Journal of Molecular Sciences, 15(4), 5762-5773. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Kessler, S M, Simon, Y, Gemperlein, K, Gianmoena, K, Cadenas, C, Zimmer, V, Pokorny, J, Barghash, A, Helms, V, van Rooijen, N, Bohle, R M, Lammert, F, Hengstler, J G, Mueller, R, Haybaeck, J & Kiemer, A K 2014, ' Fatty Acid Elongation in Non-Alcoholic Steatohepatitis and Hepatocellular Carcinoma ', International Journal of Molecular Sciences, vol. 15, no. 4, pp. 5762-5773 . https://doi.org/10.3390/ijms15045762
Non-alcoholic steatohepatitis (NASH) represents a risk factor for the development of hepatocellular carcinoma (HCC) and is characterized by quantitative and qualitative changes in hepatic lipids. Since elongation of fatty acids from C16 to C18 has re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f4e1c74615432c6c859998806ab618
Autor:
Rolf Müller, Kathrin I. Mohr, Stefanie P. Glaeser, Joachim Wink, Peter Schumann, Katja Gemperlein, Ulrich Nübel, Peter Kämpfer, Azam Moradi
Publikováno v:
International Journal of Systematic and Evolutionary Microbiology. 68:721-729
An orange-coloured myxobacterium, MNa11734T, was isolated from desert in Iran. MNa11734T had rod-shaped vegetative cells, moved by gliding and was bacteriolytic. No real fruiting body formation could be observed, but sporangioles were produced on wat
Autor:
Katja Gemperlein, Rolf Müller, Liujie Huo, Lutz Petzke, Patrick Pilak, Michael J. Hoffmann, Silke C. Wenzel
Publikováno v:
Metabolic Engineering. 44:213-222
Coronatine (COR) represents a phytotoxin produced by several pathovars of Pseudomonas syringae. It mediates multiple virulence activities by mimicking the plant stress hormone jasmonoyl-l-isoleucine. Structurally, COR consists of a bicyclic polyketid
Autor:
Demian Dietrich, Christoph Wittmann, Silke C. Wenzel, Hubert S. Bernauer, Katja Gemperlein, Michael Kohlstedt, Gregor Zipf, Rolf Müller
Publikováno v:
Nature communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Long-chain polyunsaturated fatty acids (LC-PUFAs), particularly the omega-3 LC-PUFAs eicosapentaenoic acid (EPA), docosapentaenoic acid (DPA), and docosahexaenoic acid (DHA), have been associated with beneficial health effects. Consequently, sustaina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::456ca24110968d8a0449527e152e2615
https://hdl.handle.net/10033/621938
https://hdl.handle.net/10033/621938