Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Katja Dinkelborg"'
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Akademický článek
Dynamic evolution of the sofosbuvir-associated variant A1343V in HEV-infected patients under concomitant sofosbuvir-ribavirin treatment
Autor: André Gömer, Katja Dinkelborg, Mara Klöhn, Michelle Jagst, Michael Hermann Wißing, Nicola Frericks, Pia Nörenberg, Patrick Behrendt, Markus Cornberg, Heiner Wedemeyer, Eike Steinmann, Benjamin Maasoumy, Daniel Todt
Publikováno v: JHEP Reports, Vol 6, Iss 3, Pp 100989- (2024)
Background & Aims: In the absence of a hepatitis E virus (HEV)-specific antiviral treatment, sofosbuvir has recently been shown to have antiviral activity against HEV in vivo. However, a variant, A1343V, that is strongly associated with viral relapse
Externí odkaz: https://doaj.org/article/ca23583ef8d0487da1ab21c7ddd9e36c
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6
The Human Liver-Expressed Lectin CD302 Restricts Hepatitis C Virus Infection
Autor: Birthe Reinecke, Nicola Frericks, Chris Lauber, Katja Dinkelborg, Alina Matthaei, Florian W. R. Vondran, Patrick Behrendt, Sibylle Haid, Richard J. P. Brown, Thomas Pietschmann
Publikováno v: Journal of Virology. 96
The liver represents an immunoprivileged organ characterized by enhanced resistance to immune responses. However, the importance of liver cell-endogenous, noncytolytic innate immune responses in pathogen control is not well defined.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21afba69f65f10907c6b6efc90b117a
https://doi.org/10.1128/jvi.01995-21
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8
Synthesis of the HIF-2α translation inhibitor compound 76 via a Japp-Klingemann coupling
Autor: Xiao Wang, Kevin J. Hodgetts, Othon Iliopoulos, Katja Dinkelborg, Shao-Liang Zheng, Dawid K. Fiejtek, Jung-Eun Ahn, Lin Lin, Ravi Sundaram
Publikováno v: Tetrahedron Letters. 60:983-985
The Iliopoulos laboratory previously reported the discovery of compound 76, a small molecule HIF2α inhibitor. HIF2α activation is known to play a critical role in both von Hippel-Lindau (VHL) disease-related tumors and sporadic renal cell carcinoma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9175449fef08253eef56d41b9d0b792f
https://doi.org/10.1016/j.tetlet.2019.03.005
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9
Early onset renal cell carcinoma in an adolescent girl with germline FLCN exon 5 deletion
Autor: Mukesh G. Harisinghani, Othon Iliopoulos, Katja Dinkelborg, Dongli Huang, Kathleen S. Hruska, Xiuli Xiao, Meike Schneider, Gayun Chan-Smutko, Pallavi Sagar
Publikováno v: Familial Cancer. 17:135-139
Birt-Hogg-Dube (BHD) disease is an autosomal dominant cancer syndrome characterized by benign skin tumors, renal cancer and spontaneous pneumothorax and is caused by mutations in the Folliculin (FLCN) gene. Benign skin tumors and pneumothorax occur i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1bba348c2e48da2f19dd03e63f528c8
https://doi.org/10.1007/s10689-017-0008-8
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