Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Katja C. Wolthers"'
Autor:
Pamela E. Capendale, Inés García-Rodríguez, Anoop T. Ambikan, Lance A. Mulder, Josse A. Depla, Eline Freeze, Gerrit Koen, Carlemi Calitz, Vikas Sood, Renata Vieira de Sá, Ujjwal Neogi, Dasja Pajkrt, Adithya Sridhar, Katja C. Wolthers
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Picornaviruses are a leading cause of central nervous system (CNS) infections. While genotypes such as parechovirus A3 (PeV-A3) and echovirus 11 (E11) can elicit severe neurological disease, the highly prevalent PeV-A1 is not associated with
Externí odkaz:
https://doaj.org/article/bda8e7616a1141d5a3a550360afea61c
Autor:
Nening M. Nanlohy, Nina Johannesson, Lucas Wijnands, Laura Arroyo, Jelle de Wit, Gerco den Hartog, Katja C. Wolthers, Adithya Sridhar, Susana Fuentes
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109771- (2024)
Summary: Host and microbiome intricately interact in the ecosystem of the human digestive tract, playing a crucial role in our health. These interactions can initiate immune responses in the epithelial cells, which, in turn, activate downstream respo
Externí odkaz:
https://doaj.org/article/553d6c2d90d447a79d3388e3c42bb6d9
Autor:
Georgios Stroulios, Tyler Brown, Giulia Moreni, Douglas Kondro, Alessandro Dei, Allen Eaves, Sharon Louis, Juan Hou, Wing Chang, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar, Salvatore Simmini
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Airway organoids are polarized 3D epithelial structures that recapitulate the organization and many of the key functions of the in vivo tissue. They present an attractive model that can overcome some of the limitations of traditional 2D and
Externí odkaz:
https://doaj.org/article/0d5f0d05c1cd42b89ea970cb80e10112
Autor:
Ikrame Aknouch, Inés García-Rodríguez, Francesca Paola Giugliano, Carlemi Calitz, Gerrit Koen, Hetty van Eijk, Nina Johannessson, Sjoerd Rebers, Lieke Brouwer, Vanesa Muncan, Koert J. Stittelaar, Dasja Pajkrt, Katja C. Wolthers, Adithya Sridhar
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Enterovirus A71 (EV-A71) can elicit a wide variety of human diseases such as hand, foot, and mouth disease and severe or fatal neurological complications. It is not clearly understood what determines the virulence and fitness of EV-A71. It has been o
Externí odkaz:
https://doaj.org/article/0c91f880a92f4ad5b2a6ecbaed1e1cc4
Autor:
Julia Eder, Esther Zijlstra-Willems, Gerrit Koen, Neeltje A. Kootstra, Katja C. Wolthers, Teunis B. Geijtenbeek
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Zika virus is a member of the Flaviviridae family that has caused recent outbreaks associated with neurological malformations. Transmission of Zika virus occurs primarily via mosquito bite but also via sexual contact. Dendritic cells (DCs) and Langer
Externí odkaz:
https://doaj.org/article/9e975dbda00f40ac809de32539335eca
Autor:
Angelica Reitsma, Edo Roos Lindgreen, Dara Satrio, Vanessa Rijkeboer, Dasja Pajkrt, Katja C. Wolthers
Publikováno v:
Open Research Europe, Vol 3 (2023)
Science industries, such as the health and medical industry, are experiencing increases in competition regarding commercializing, patenting, and funding of scientific outputs. As such, scientists are facing increased expectation to engage in academic
Externí odkaz:
https://doaj.org/article/80bc1c2df3a84926ba92cd907ec140bc
Autor:
Leanne C. Helgers, Michel S. Bhoekhan, Dasja Pajkrt, Katja C. Wolthers, Teunis B. H. Geijtenbeek, Adithya Sridhar
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 6 (2022)
ABSTRACT Enterovirus A71 (EV-A71) is a causative agent of life-threatening neurological diseases in young children. EV-A71 is highly infectious but it remains unclear how the virus disseminates from primary entry sites—the mucosa of the respiratory
Externí odkaz:
https://doaj.org/article/5c3474efdaa54defa714e24426b412a4
Autor:
Adithya Sridhar, Josse A. Depla, Lance A. Mulder, Eveliina Karelehto, Lieke Brouwer, Leonie Kruiswijk, Renata Vieira de Sá, Adam Meijer, Melvin M. Evers, Frank J. M. van Kuppeveld, Dasja Pajkrt, Katja C. Wolthers
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Enterovirus D68 (EV-D68) is an RNA virus that can cause outbreaks of acute flaccid paralysis (AFP), a polio-like disease. Before 2010, EV-D68 was a rare pathogen associated with mild respiratory symptoms, but the recent EV-D68 related increa
Externí odkaz:
https://doaj.org/article/21f27dcb3b52466392561c972a72bd2c
Autor:
Kimberley S.M. Benschop, Eeva K. Broberg, Emma Hodcroft, Dennis Schmitz, Jan Albert, Anda Baicus, Jean-Luc Bailly, Gudrun Baldvinsdottir, Natasa Berginc, Soile Blomqvist, Sindy Böttcher, Mia Brytting, Erika Bujaki, Maria Cabrerizo, Cristina Celma, Ondrej Cinek, Eric C.J. Claas, Jeroen Cremer, Jonathan Dean, Jennifer L. Dembinski, Iryna Demchyshyna, Sabine Diedrich, Susanne Dudman, Jake Dunning, Robert Dyrdak, Mary Emmanouil, Agnes Farkas, Cillian De Gascun, Guillaume Fournier, Irina Georgieva, Ruben Gonzalez-Sanz, Jolanda van Hooydonk-Elving, Anne J. Jääskeläinen, Ruta Jancauskaite, Kathrin Keeren, Thea K. Fischer, Sidsel Krokstad, Lubomira Nikolaeva–Glomb, Ludmila Novakova, Sofie E. Midgley, Audrey Mirand, Richard Molenkamp, Ursula Morley, Joël Mossong, Svajune Muralyte, Jean-Luc Murk, Trung Nguyen, Svein A. Nordbø, Riikka Österback, Suzan Pas, Laura Pellegrinelli, Vassiliki Pogka, Birgit Prochazka, Petra Rainetova, Marc Van Ranst, Lieuwe Roorda, Isabelle Schuffenecker, Rob Schuurman, Asya Stoyanova, Kate Templeton, Jaco J. Verweij, Androniki Voulgari-Kokota, Tytti Vuorinen, Elke Wollants, Katja C. Wolthers, Katherina Zakikhany, Richard Neher, Heli Harvala, Peter Simmonds
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 6, Pp 1616-1626 (2021)
In 2018, an upsurge in echovirus 30 (E30) infections was reported in Europe. We conducted a large-scale epidemiologic and evolutionary study of 1,329 E30 strains collected in 22 countries in Europe during 2016–2018. Most E30 cases affected persons
Externí odkaz:
https://doaj.org/article/c6458fb750c44d5db7a5e3220d8d57d9
Autor:
Giulia Moreni, Ikrame Aknouch, Morris Ras, Lieke Brouwer, René Spijker, Carlemi Calitz, Koert J. Stittelaar, Adithya Sridhar, Katja C. Wolthers, Dasja Pajkrt
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 2, Pp n/a-n/a (2022)
Abstract Disease modelling plays a fundamental role in biomedical research, even more in virology where the virus depends strictly on its host for replication. Although animal models are extensively used in virology, there is an increasing demand for
Externí odkaz:
https://doaj.org/article/d4995a7846e44029b329068fa786f57a