Výsledky vyhledávání - "Katja Blunert"

Recombinant human beta 2-defensin fusion proteins as a tool to investigate defensin structure and function in small human intestinal tissue samples

Autor: Andreas Andreou, Katja Blunert, Annekatrin Coordes, Britta Siegmund, Anton J. Kroesen, Ulrike Erben, N. Slavova, Heinz-Johannes Buhr, T. Stroh

Publikováno v: Inflammation Research. 61:1411-1420

Effects of immune cells on the beta 2 (β2)-defensin (HBD2) expression and its antibacterial activity in the intestinal mucosa of patients with inflammatory bowel diseases remains unclear. The small size of these proteins presents a major challenge i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61339c3a766736ce21abb4a56b416a1d
https://doi.org/10.1007/s00011-012-0544-5

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Inhibition of IGF1-R overcomes IGFBP7-induced chemotherapy resistance in T-ALL

Autor: Martin Neumann, Katja Blunert, Jutta Ortiz-Tanchez, Cornelia Schlee, Sandra Heesch, Ulrike Erben, Claudia D. Baldus, Isabelle Bartram

Publikováno v: BMC Cancer

Background T-cell acute lymphoblastic leukemia (T-ALL) is a genetically heterogeneous disease with the need for treatment optimization. Previously, high expression of Insulin-like growth factor binding protein 7 (IGFBP7), a member of the IGF system,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d6eae96f3b04369e336ddfdce1c434
http://europepmc.org/articles/PMC4599323

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Expression of functional T-cell markers and T-cell receptor Vbeta repertoire in endomyocardial biopsies from patients presenting with acute myocarditis and dilated cardiomyopathy

Autor: Dirk Lassner, Lara Hemaidan, Hans-Dieter Volk, Maria Rohde, Jan-Henrik Blohm, Andrea Block, Katja Blunert, Michel Noutsias, Heinz-Peter Schultheiss, Uwe Kühl, Katja Kotsch, Katrin Göldner, Michael Hummel

Publikováno v: European journal of heart failure. 13(6)

Aims To quantify and functionally characterize the intramyocardial T-cells in endomyocardial biopsies (EMBs) from patients presenting with acute myocarditis (AMC) and dilated cardiomyopathy (DCM). Methods and results Expression of genes characterizin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef964a04ebb5b2050edca514cf342a0
https://pubmed.ncbi.nlm.nih.gov/21422001

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Impact of cell culture media on the expansion efficiency and T-cell receptor Vbeta (TRBV) repertoire of in vitro expanded T cells using feeder cells

Autor: Andrea, Block, Maria, Rohde, Ulrike, Erben, Markus, Hammer, Michael, Hummel, Katja, Blunert, Heinz-Peter, Schultheiss, Hans-Dieter, Volk, Michel, Noutsias

Publikováno v: Medical science monitor : international medical journal of experimental and clinical research. 14(5)

The effects of different cell culture media on expansion efficiency and alterations in T-cell receptor V beta (TRBV) expression of in vitro expanded lymphocytes are not well established.Low numbers of CD3+ T cells from peripheral blood lymphocytes of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8cc6162084c4a003650f6b1efd5e08c5
https://pubmed.ncbi.nlm.nih.gov/18443543

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Etablierung eines Nachweises direkter antibakterieller Wirkung humaner Defensine für die Untersuchung der Defensinproduktion im menschlichen Darm bei Patienten mit Morbus Crohn und Colitis ulcerosa

Autor: Annekatrin Coordes, Katja Blunert, A. J. Kroesen, Andreas Andreou, Heinz-Johannes Buhr, Ulrike Erben, N. Slavova

Publikováno v: 125. Kongress der Deutschen Gesellschaft für Chirurgie; 20080422-20080425; Berlin; DOC08dgch9720 /20080416/
Chirurgisches Forum 2008 ISBN: 9783540788218

As a part of the innate immunity, defensins support the preservation of the intestinal mucosal barrier which is affected in IBD patients. It is interesting whether a potential direct antibacterial activity of defensins in the bowel of IBD patients is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::997b2b167ab9e8845f6cee575334a83a
http://www.egms.de/en/meetings/dgch2008/08dgch463.shtml

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Einfluss proinflammatorischer Zytokine auf die Expression von humanem ß2-Defensin in Darmepithelien — In-vitro-Untersuchungen im Modell mit der epithelialen Zelllinie HT-29

Autor: Katja Blunert, N. Slavova, Annekatrin Coordes, Ulrike Erben, J. H. Buhr, Anton J. Kroesen, T. Stroh, Andreas Andreou

Publikováno v: Chirurgisches Forum 2008 ISBN: 9783540788218

In Crohn’s disease an altered intestine mucosal barrier and cellular cytokine-mediated immune responses against commensal flora was described before. Taking part in the barrier function, human β2-defensin (HBD-2) is transcriptionally regulated but

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::554e07067d05f0594a330c1bb3ca17c6
https://doi.org/10.1007/978-3-540-78833-1_53

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Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies

Autor: Katja Kotsch, Uwe Kühl, Michael Hummel, Ursula Rauch, Hans B. Lehmkuhl, Roland Hetzer, Katja Blunert, Heinz P. Schultheiss, H.-D. Volk, Katrin Klippert, Matthias Pauschinger, Maria Rohde, Wolfgang Poller, Andrea Block, Michel Noutsias, Olga Lettau

Publikováno v: BMC Molecular Biology, Vol 9, Iss 1, p 3 (2008)
BMC Molecular Biology

Background Due to the limited RNA amounts from endomyocardial biopsies (EMBs) and low expression levels of certain genes, gene expression analyses by conventional real-time RT-PCR are restrained in EMBs. We applied two preamplification techniques, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b6ea2f301affe1a4257d9b46ce03ef
http://www.biomedcentral.com/1471-2199/9/3

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Akademický článek

Preamplification techniques for real-time RT-PCR analyses of endomyocardial biopsies.

Autor: Noutsias, Michel¹ michel.noutsias@charite.de, Rohde, Maria¹ maria.rohde@charite.de, Block, Andrea¹ andrea.block@charite.de, Klippert, Katrin² katrin.klippert@charite.de, Lettau, Olga¹ volha.khakhlova@charite.de, Blunert, Katja^1,3 Katja.Blunert@charite.de, Hummel, Michael michael.hummel@charite.de, Kühl, Uwe¹ uwe.kuehl@charite.de, Lehmkuhl, Hans⁴ lehmkuhl@dhzb.de, Hetzer, Roland⁴ hetzer@dhzb.de, Rauch, Ursula¹ ursula.rauch@charite.de, Poller, Wolfgang¹ wolfgang.poller@charite.de, Pauschinger, Matthias¹ Matthias.Pauschinger@charite.de, Schultheiss, Heinz P.¹ heinz-peter.schultheiss@charite.de, Volk, Hans D.² hansdietervolk@charite.de, Kotsch, Katja² katja.kotsch@charite.de

Publikováno v: BMC Molecular Biology. 2008, Vol. 9, Special section p1-20. 20p. 2 Diagrams, 5 Charts, 11 Graphs.

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