Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Katja, Porvari"'
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Amphiregulin (AREG) is a growth factor linked to cardioprotection and heart pathology during myocardial stress. Our aim was to investigate cardiac AREG expression, its potential as a postmortem hypothermia marker and its possible stress ho
Externí odkaz:
https://doaj.org/article/d9f1aaf417954498b059c54afef73e08
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 44, Iss , Pp 100933- (2023)
Different sources of mutagenesis cause consistently identifiable patterns of mutations and mutational signatures that mirror the various carcinogenetic processes. We used publicly available data from the Cancer Genome Atlas to evaluate the associatio
Externí odkaz:
https://doaj.org/article/d01b28bbb0d94482abdf40baced304e6
Autor:
Peeter Karihtala, Katja Porvari, Nelli Roininen, Sari Voutilainen, Johanna Mattson, Päivi Heikkilä, Kirsi-Maria Haapasaari, Katri Selander
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-11 (2022)
Abstract The pathophysiology and the optimal treatment of breast neuroendocrine tumours (NETs) are unknown. We compared the mutational profiles of breast NETs (n = 53) with those of 724 publicly available invasive ductal carcinoma (IDC) and 98 pancre
Externí odkaz:
https://doaj.org/article/2af5b7589630403baeb90a0af5c02b58
Autor:
Mervi Kreus, Siri Lehtonen, Reetta Hinttala, Johanna Salonen, Katja Porvari, Riitta Kaarteenaho
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Variants of NHL repeat-containing protein 2 (NHLRC2) have been associated with severe fibrotic interstitial lung disease in early childhood and NHLRC2 has been listed as a differentially expressed gene between rapidly and slowly p
Externí odkaz:
https://doaj.org/article/57dbc3a669f743c5b2f09e355361a78a
Autor:
Lauri Holmström, Katri Pylkäs, Anna Tervasmäki, Juha Vähätalo, Katja Porvari, Lasse Pakanen, Kari S. Kaikkonen, Juha S. Perkiömäki, Antti M. Kiviniemi, Risto Kerkelä, Olavi Ukkola, Robert J. Myerburg, Heikki V. Huikuri, Juhani Junttila
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract The contribution of genetic variants to non-ischemic sudden cardiac death (SCD) due to acquired myocardial diseases is unclear. We studied whether SCD victims with hypertension/obesity related hypertrophic myocardial disease harbor potential
Externí odkaz:
https://doaj.org/article/114df0d571394915b5cd3f2ed4d33d2b
Autor:
Janna P. Kauppila, Lasse Pakanen, Katja Porvari, Juha Vähätalo, Lauri Holmström, Juha S. Perkiömäki, Heikki V. Huikuri, M. Juhani Junttila
Publikováno v:
Annals of Medicine, Vol 53, Iss 1, Pp 413-419 (2021)
AbstractIntroduction Non-ischaemic heart disease (NIHD) is the underlying pathology in∼20% of all sudden cardiac deaths (SCDs). Heavy drinking is known to be associated with SCD due to ischaemic heart disease, but studies on association of recent a
Externí odkaz:
https://doaj.org/article/fb1b597cfaf84dc590b3ae49da814762
Autor:
Ruizhu Lin, Lea Rahtu-Korpela, Johanna Magga, Johanna Ulvila, Julia Swan, Anna Kemppi, Lasse Pakanen, Katja Porvari, Heikki Huikuri, Juhani Junttila, Risto Kerkelä
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 20, Iss , Pp 589-605 (2020)
Non-coding microRNAs (miRNAs) are powerful regulators of gene expression and critically involved in cardiovascular pathophysiology. The aim of the current study was to identify miRNAs regulating cardiac fibrosis. Cardiac samples of age-matched contro
Externí odkaz:
https://doaj.org/article/a2aaa49b59974543a479eb83c8b3b525
Autor:
Juha H. Vähätalo, Lauri T. A. Holmström, Katri Pylkäs, Sini Skarp, Katja Porvari, Lasse Pakanen, Kari S. Kaikkonen, Juha S. Perkiömäki, Risto Kerkelä, Heikki V. Huikuri, Robert J. Myerburg, M. Juhani Junttila
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Objective: Cardiac hypertrophy with varying degrees of myocardial fibrosis is commonly associated with coronary artery disease (CAD) related sudden cardiac death (SCD), especially in young victims among whom patterns of coronary artery lesions do not
Externí odkaz:
https://doaj.org/article/7008680141cb4bbdb6bdc83a3d9b110e
Autor:
Jere Paavola, Tarja Alakoski, Johanna Ulvila, Teemu Kilpiö, Juuso Sirén, Sanni Perttunen, Suneeta Narumanchi, Hong Wang, Ruizhu Lin, Katja Porvari, Juhani Junttila, Heikki Huikuri, Katariina Immonen, Päivi Lakkisto, Johanna Magga, Ilkka Tikkanen, Risto Kerkelä
Publikováno v:
EBioMedicine, Vol 51, Iss , Pp - (2020)
Background: Vascular endothelial zinc finger 1 (Vezf1) is a transcription factor previously shown to regulate vasculogenesis and angiogenesis. We aimed to investigate the role of Vezf1 in the postnatal heart. Methods: The role of Vezf1 in regulating
Externí odkaz:
https://doaj.org/article/3c77abab2ac34b3ca0fbf694d31d866e
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: Mutational signatures reflect common patterns based on the counts of mutations and their sequence context. The prognostic value of these signatures, mirroring various carcinogenetic processes of cancers, are unexplored in gastrointest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3dcdef28385a4b58785ef5f10f7a2c
https://doi.org/10.21873/cgp.20340
https://doi.org/10.21873/cgp.20340