Výsledky vyhledávání - "Katja, Maurus"

Akademický článek

Rapid response to selpercatinib in RET fusion positive pancreatic neuroendocrine carcinoma confirmed by smartwatch

Autor: Barbara Deschler-Baier, Markus Krebs, Matthias Kroiss, Manik Chatterjee, Daniel Gundel, Christian Kestler, Alexander Kerscher, Volker Kunzmann, Silke Appenzeller, Katja Maurus, Andreas Rosenwald, Ralf Bargou, Elena Gerhard-Hartmann, Vivek Venkataramani

Publikováno v: npj Precision Oncology, Vol 8, Iss 1, Pp 1-6 (2024)

Abstract This case report describes the efficacy of selpercatinib, a selective RET inhibitor, in an unusual case of large-cell neuroendocrine pancreatic carcinoma (LCNEPAC) harboring a CCDC6::RET fusion. A 56-year-old male with a history of multiple

Externí odkaz: https://doaj.org/article/506d531186bd4f8ab0f4e6ef49c5a07e

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Akademický článek

Targeted panel sequencing in the routine diagnosis of mature T- and NK-cell lymphomas: report of 128 cases from two German reference centers

Autor: Julia Böck, Katja Maurus, Elena Gerhard-Hartmann, Stephanie Brändlein, Katrin S. Kurz, German Ott, Ioannis Anagnostopoulos, Andreas Rosenwald, Alberto Zamò

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

Diagnosing any of the more than 30 types of T-cell lymphomas is considered a challenging task for many pathologists and currently requires morphological expertise as well as the integration of clinical data, immunophenotype, flow cytometry and clonal

Externí odkaz: https://doaj.org/article/e2abd8b5956b43c080db509510797b81

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Akademický článek

A large retroperitoneal lipoblastoma as an incidental finding: a case report

Autor: Elena Gerhard-Hartmann, Verena Wiegering, Clemens Benoit, Thomas Meyer, Andreas Rosenwald, Katja Maurus, Karen Ernestus

Publikováno v: BMC Pediatrics, Vol 21, Iss 1, Pp 1-6 (2021)

Abstract Background Lipoblastoma is a rare benign mesenchymal neoplasm of infancy that most commonly occurs on the extremities and trunk but can arise at variable sites of the body. Retroperitoneal lipoblastomas are particularly rare but can grow to

Externí odkaz: https://doaj.org/article/8434f5c4797f4c4fb583e5eb49828a31

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Akademický článek

Recurrent Alterations in the MAPK pathway in Sporadic Pyogenic Granuloma of Childhood

Autor: Katharina Strobel, Katja Maurus, Henning Hamm, Sabine Roth, Matthias Goebeler, Andreas Rosenwald, Marion Wobser

Publikováno v: Acta Dermato-Venereologica, Vol 102 (2022)

Pyogenic granuloma is one of the most common vascular tumours. The cause of pyogenic granuloma was previously thought to be an inflammatory reaction with consecutive stimulation of endothelial cell proliferation. However, recent studies suggest that

Externí odkaz: https://doaj.org/article/8f9a333a30794886b0e4172b399c2b2e

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Akademický článek

Autophagy Blockage Reduces the Incidence of Pancreatic Ductal Adenocarcinoma in the Context of Mutant Trp53

Autor: Laura Mainz, Mohamed A. F. E. Sarhan, Sabine Roth, Ursula Sauer, Katja Maurus, Elena M. Hartmann, Helen-Desiree Seibert, Andreas Rosenwald, Markus E. Diefenbacher, Mathias T. Rosenfeldt

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Macroautophagy (hereafter referred to as autophagy) is a homeostatic process that preserves cellular integrity. In mice, autophagy regulates pancreatic ductal adenocarcinoma (PDAC) development in a manner dependent on the status of the tumor suppress

Externí odkaz: https://doaj.org/article/a7fcc1ac5ba54c5c8755dbee66ebd6bc

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Akademický článek

Protein-Based Oncopanel as Addition to Target Sequencing in Head and Neck Squamous Cell Carcinoma to Individualize Treatment Decisions

Autor: Adrian von Witzleben, Urs Müller-Richter, Katja Maurus, Stephanie Brändlein, Marie-Nicole Theodoraki, Cornelia Brunner, Simon Laban, Jochen Lennerz, Peter Möller, Thomas K. Hoffmann, Johannes Doescher, Patrick J. Schuler

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 24, p 15835 (2022)

Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group of cancers and patients have limited therapy options if primary treatment fails. Therefore, additional information about the biology of the tumor is essential. Here we performed a

Externí odkaz: https://doaj.org/article/abb4c3ab69d940c588fb3edeb1ba2d7e

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Akademický článek

Oncogenic Mutations and Gene Fusions in CD30-Positive Lymphoproliferations and Clonally Related Mycosis Fungoides Occurring in the Same Patients

Autor: Marion Wobser, Sabine Roth, Silke Appenzeller, Hermann Kneitz, Matthias Goebeler, Eva Geissinger, Andreas Rosenwald, Katja Maurus

Publikováno v: JID Innovations, Vol 1, Iss 3, Pp 100034- (2021)

The emergence of a common progenitor cell has been postulated for the association of CD30-positive lymphoproliferative disease (LPD) and mycosis fungoides (MF) within the same patient. Up to now, no comprehensive analysis has yet addressed the geneti

Externí odkaz: https://doaj.org/article/5634720f363649ddb7447f0fbb6f4bed

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