Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Katja, Giersch"'
Autor:
Katja Giersch, Konstantin Tanida, Anna Both, Dominik Nörz, Denise Heim, Holger Rohde, Martin Aepfelbacher, Marc Lütgehetmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Vancomycin resistant enterococci (VRE) are a leading cause of ICU-acquired bloodstream infections in Europe. The bacterial load in enteral colonization may be associated with a higher probability of transmission. Here, we aimed to establish
Externí odkaz:
https://doaj.org/article/20e3e2d2ade84227b5dc6f7ee097d931
Autor:
Lisa Sophie Pflüger, Dominik Nörz, Moritz Grunwald, Susanne Pfefferle, Katja Giersch, Martin Christner, Beatrice Weber, Martin Aepfelbacher, Holger Rohde, Marc Lütgehetmann
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 3 (2024)
ABSTRACTFor effective infection control measures for Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG), a reliable tool for screening and diagnosis is essential. Here, we aimed to establish and validate a multiplex PCR assay on an automated s
Externí odkaz:
https://doaj.org/article/33e557bf82084615bfbb9f584091eedb
Autor:
Dominik Nörz, Hui Ting Tang, Petra Emmerich, Katja Giersch, Nicole Fischer, Stephan Schmiedel, Marylyn M. Addo, Martin Aepfelbacher, Susanne Pfefferle, Marc Lütgehetmann
Publikováno v:
Emerging Infectious Diseases, Vol 28, Iss 9, Pp 1765-1769 (2022)
Beginning in May 2022, a rising number of monkeypox cases were reported in non–monkeypox-endemic countries in the Northern Hemisphere. We adapted 2 published quantitative PCRs for use as a dual-target monkeypox virus test on widely used automated h
Externí odkaz:
https://doaj.org/article/aca478786aa6465baf32eb3092b66b42
Autor:
Katja Giersch, Paulina Perez-Gonzalez, Lennart Hendricks, Nora Goldmann, Jonathan Kolbe, Lennart Hermanussen, Jan-Hendrick Bockmann, Tassilo Volz, Annika Volmari, Lena Allweiss, Joerg Petersen, Dieter Glebe, Marc Lütgehetmann, Maura Dandri
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100673- (2023)
Background & Aims: Pegylated interferon alpha (pegIFNα) is commonly used for the treatment of people infected with HDV. However, its mode of action in HDV-infected cells remains elusive and only a minority of people respond to pegIFNα therapy. Here
Externí odkaz:
https://doaj.org/article/01d54f34c762458ab95d9601864425ef
Autor:
Jan-Hendrik Bockmann, Marcel Grube, Vanessa Hamed, Johann von Felden, Johanna Landahl, Malte Wehmeyer, Katja Giersch, Michaela T. Hall, John M. Murray, Maura Dandri, Stefan Lüth, Ansgar W. Lohse, Marc Lütgehetmann, Julian Schulze Zur Wiesch
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-6 (2020)
Abstract Background Chronic hepatitis delta virus (HDV) infection causes severe liver disease which often leads to cirrhosis and hepatocellular carcinoma (HCC). Aim of this study was to establish the disease severity and prognostic factors for diseas
Externí odkaz:
https://doaj.org/article/b9dae382d5d04768b43955c7ffae2288
Autor:
Lisa Sophie Pflüger, Dominik Nörz, Tassilo Volz, Katja Giersch, Annika Giese, Nora Goldmann, Dieter Glebe, Jan-Hendrik Bockmann, Susanne Pfefferle, Maura Dandri, Julian Schulze zur Wiesch, Marc Lütgehetmann
Publikováno v:
JHEP Reports, Vol 3, Iss 6, Pp 100356- (2021)
Background & Aims: Currently available HDV PCR assays are characterized by considerable run-to-run and inter-laboratory variability. Hence, we established a quantitative reverse transcription real-time PCR (RT-qPCR) assay on the open channel of a ful
Externí odkaz:
https://doaj.org/article/f3d9aadcae3c49dab7c4fe5a8f856e86
Autor:
Katja Giersch, Lennart Hermanussen, Tassilo Volz, Annika Volmari, Lena Allweiss, Camille Sureau, John Casey, Jiabin Huang, Nicole Fischer, Marc Lütgehetmann, Maura Dandri
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
BackgroundHepatitis D Virus (HDV) is classified into eight genotypes with distinct clinical outcomes. Despite the maintenance of highly conserved functional motifs, it is unknown whether sequence divergence between genotypes, such as HDV-1 and HDV-3,
Externí odkaz:
https://doaj.org/article/6217e92b09c84254849aad0d31065465
Autor:
Dominik Nörz, Moritz Grunwald, Hui Ting Tang, Celine Weinschenk, Thomas Günther, Alexis Robitaille, Katja Giersch, Nicole Fischer, Adam Grundhoff, Martin Aepfelbacher, Susanne Pfefferle, Marc Lütgehetmann
Publikováno v:
Viruses, Vol 14, Iss 3, p 608 (2022)
Background: The recently emerged SARS-CoV-2 B.1.1.529 lineage and its sublineages (Omicron variant) pose a new challenge to healthcare systems worldwide due to its ability to efficiently spread in immunized populations and its resistance to currently
Externí odkaz:
https://doaj.org/article/f5a32ecc5c3a4ed3ab35a89360342224
Autor:
Christine Y.L. Tham, Janine Kah, Anthony T. Tan, Tassilo Volz, Adeline Chia, Katja Giersch, Yvonne Ladiges, Alessandro Loglio, Marta Borghi, Camille Sureau, Pietro Lampertico, Marc Lütgehetmann, Maura Dandri, Antonio Bertoletti
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 4, Pp 100060- (2020)
Summary: Hepatitis delta virus (HDV) requires hepatitis B virus (HBV) to complete its infection cycle and causes severe hepatitis, with limited therapeutic options. To determine the prospect of T cell therapy in HBV/HDV co-infection, we study the imp
Externí odkaz:
https://doaj.org/article/6d4ddfe9419f438f9c91e9142a2b1cb6
Autor:
Katja Giersch, Maria Homs, Tassilo Volz, Martina Helbig, Lena Allweiss, Ansgar W. Lohse, Jörg Petersen, Maria Buti, Teresa Pollicino, Camille Sureau, Maura Dandri, Marc Lütgehetmann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Co-infection with hepatitis B (HBV) and D virus (HDV) is associated with the most severe course of liver disease. Interferon represents the only treatment currently approved. However, knowledge about the impact of interferons on HDV in human
Externí odkaz:
https://doaj.org/article/9e42cac1eded48feb29e6600c0ba9101