Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Katja, Dahlgaard"'
Autor:
Sylvester Larsen, Jakob Benedict Seidelin, Johanne Davidsen, Katja Dahlgaard, Claus Henrik Nielsen, Eric Paul Bennett, Ole Birger Pedersen, Mehmet Coskun, Jesper Thorvald Troelsen
Publikováno v:
FEBS Open Bio, Vol 11, Iss 6, Pp 1638-1644 (2021)
Dysregulation of interleukin‐33 (IL‐33) has been implicated in the pathogenesis of several autoimmune and inflammatory diseases, but few studies have examined transcriptional regulation of the IL33 gene. In the intestines, gene regulation is cont
Externí odkaz:
https://doaj.org/article/5549bbf033ae437c8ddbb6bbcc6e4cc4
Autor:
Johanne Davidsen, Stine Bull Jessen, Sara Kehlet Watt, Sylvester Larsen, Katja Dahlgaard, Tove Kirkegaard, Ismail Gögenur, Jesper T. Troelsen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Colon cancer is one of the most commonly diagnosed types of cancer with surgical resection of the tumor being the primary choice of treatment. However, the surgical stress response induced during treatment may be related to a high
Externí odkaz:
https://doaj.org/article/eba229a27dc84e4fbfbc33651debd881
Colorectal cancer-associated SNP rs17042479 is involved in the regulation of NAF1 promoter activity.
Autor:
Josephine B Olsson, Marietta B Gugerel, Stine B Jessen, Jannie Jørgensen, Ismail Gögenur, Camilla Hansen, Lene T Kirkeby, Jørgen Olsen, Ole B V Pedersen, Peter M Vestlev, Katja Dahlgaard, Jesper T Troelsen
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0274033 (2022)
A novel risk locus at 4q32.2, located between the Nuclear Assembly Factor 1 (NAF1) and Follistatin Like 5 (FSTL5) genes, was associated with increased risk of developing colorectal cancer (CRC), with SNP rs17042479 being the most associated. However,
Externí odkaz:
https://doaj.org/article/cbbae98fee5b4b73878dbb965057c357
Autor:
Mette Boyd, Malte Thodberg, Morana Vitezic, Jette Bornholdt, Kristoffer Vitting-Seerup, Yun Chen, Mehmet Coskun, Yuan Li, Bobby Zhao Sheng Lo, Pia Klausen, Pawel Jan Schweiger, Anders Gorm Pedersen, Nicolas Rapin, Kerstin Skovgaard, Katja Dahlgaard, Robin Andersson, Thilde Bagger Terkelsen, Berit Lilje, Jesper Thorvald Troelsen, Andreas Munk Petersen, Kim Bak Jensen, Ismail Gögenur, Peter Thielsen, Jakob Benedict Seidelin, Ole Haagen Nielsen, Jacob Tveiten Bjerrum, Albin Sandelin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Many SNPs associated with inflammatory bowel disease are located in non-coding genomic regions. Here, the authors perform CAGE-sequencing on descending colon biopsies of Crohn’s disease and ulcerative colitis patients to map transcription start sit
Externí odkaz:
https://doaj.org/article/e32e0b001f3f40cfa76d4515cf61a036
Autor:
Johanne Davidsen, Sylvester Larsen, Mehmet Coskun, Ismail Gögenur, Katja Dahlgaard, Eric Paul Bennett, Jesper Thorvald Troelsen
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200215 (2018)
Sequencing of primary colorectal tumors has identified a gene fusion in approximately 3% of colorectal cancer patients of the VTI1A and TCF7L2 genes, encoding a VTI1A-TCF4 fusion protein containing a truncated TCF4. As dysregulation of the Wnt signal
Externí odkaz:
https://doaj.org/article/20e939a5df2a4507b32f6975b67d522a
Autor:
Claus Henrik Nielsen, Jakob Benedict Seidelin, Mehmet Coşkun, Sylvester Larsen, Ole Birger Pedersen, Eric P. Bennett, Jesper T. Troelsen, Johanne Davidsen, Katja Dahlgaard
Publikováno v:
FEBS Open Bio, Vol 11, Iss 6, Pp 1638-1644 (2021)
FEBS Open Bio
Larsen, S, Seidelin, J B, Davidsen, J, Dahlgaard, K, Nielsen, C H, Bennett, E P, Pedersen, O B, Coskun, M & Troelsen, J T 2021, ' CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T) ', FEBS Open Bio, vol. 11, no. 6, pp. 1638-1644 . https://doi.org/10.1002/2211-5463.13161
FEBS Open Bio
Larsen, S, Seidelin, J B, Davidsen, J, Dahlgaard, K, Nielsen, C H, Bennett, E P, Pedersen, O B, Coskun, M & Troelsen, J T 2021, ' CDX2 regulates interleukin-33 gene expression in intestinal epithelial cells (LS174T) ', FEBS Open Bio, vol. 11, no. 6, pp. 1638-1644 . https://doi.org/10.1002/2211-5463.13161
Dysregulation of interleukin‐33 (IL‐33) has been implicated in the pathogenesis of several autoimmune and inflammatory diseases, but few studies have examined transcriptional regulation of the IL33 gene. In the intestines, gene regulation is cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fab30203152c777098587cfeab7452
https://doi.org/10.1002/2211-5463.13161
https://doi.org/10.1002/2211-5463.13161
Autor:
Tove Kirkegaard, Ismail Gögenur, Johanne Davidsen, Katja Dahlgaard, Jesper T. Troelsen, Sara Kehlet Watt, Sylvester Larsen, Stine Bull Jessen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
BackgroundColon cancer is one of the most commonly diagnosed types of cancer with surgical resection of the tumor being the primary choice of treatment. However, the surgical stress response induced during treatment may be related to a higher risk of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d97e4b29ccb9c1ee8604cd1071e452
https://doi.org/10.1186/s12885-020-06941-y
https://doi.org/10.1186/s12885-020-06941-y
Autor:
Johanne Davidsen, Sylvester Larsen, Ole Birger Pedersen, Jesper Thorvald Troelsen, Katja Dahlgaard
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 12
Larsen, S, Davidsen, J, Dahlgaard, K, Pedersen, O B & Troelsen, J T 2019, ' HNF4α and CDX2 Regulate Intestinal YAP1 Promoter Activity ', International Journal of Molecular Sciences, vol. 20, no. 12, 2981 . https://doi.org/10.3390/ijms20122981
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2981 (2019)
Volume 20
Issue 12
Larsen, S, Davidsen, J, Dahlgaard, K, Pedersen, O B & Troelsen, J T 2019, ' HNF4α and CDX2 Regulate Intestinal YAP1 Promoter Activity ', International Journal of Molecular Sciences, vol. 20, no. 12, 2981 . https://doi.org/10.3390/ijms20122981
International Journal of Molecular Sciences, Vol 20, Iss 12, p 2981 (2019)
The Hippo pathway is important for tissue homeostasis, regulation of organ size andgrowth in most tissues. The co‐transcription factor yes‐associated protein 1 (YAP1) serves as a maindownstream effector of the Hippo pathway and its dysregulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6571b87e911255c5919ab0bb220a85db
Publikováno v:
International Journal of Molecular Sciences
The Hippo pathway is important for tissue homeostasis, regulation of organ size and growth in most tissues. The co-transcription factor yes-associated protein 1 (YAP1) serves as a main downstream effector of the Hippo pathway and its dysregulation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2050d0702e39127ea0e37c66bb26bde4
https://pubmed.ncbi.nlm.nih.gov/31216773
https://pubmed.ncbi.nlm.nih.gov/31216773
Autor:
Katja Dahlgaard, Mehmet Coşkun, Ole Haagen Nielsen, Christoffer Soendergaard, Albin Sandelin, Steffen Joergensen, Lene Riis, Jesper T. Troelsen
Publikováno v:
Journal of Cellular Biochemistry. 118:298-307
The expression of Caudal-related homeobox transcription factor 2 (CDX2) is impaired by tumor necrosis factor-α (TNF-α)-mediated activation of nuclear factor-κB (NF-κB) in ulcerative colitis (UC). Laminin subunit γ2 (LAMC2) is an epithelial basem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4ab7fd5952e060cdebcd2d4e3f6ecb6
https://doi.org/10.1002/jcb.25636
https://doi.org/10.1002/jcb.25636