Zobrazeno 1 - 10
of 501
pro vyhledávání: '"Katja, Becker"'
Autor:
Sabrina Baldofski, Jelena Scheider, Elisabeth Kohls, Sarah-Lena Klemm, Julian Koenig, Stephanie Bauer, Markus Moessner, Michael Kaess, Heike Eschenbeck, Laya Lehner, Katja Becker, Jennifer Krämer, Silke Diestelkamp, Rainer Thomasius, Christine Rummel-Kluge, the ProHEAD Consortium
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 18, Iss 1, Pp 1-13 (2024)
Abstract Background Mental health problems, such as depression, have a high prevalence in young people. However, the majority of youths suffering from depression do not seek professional help. This study aimed to compare help-seeking behavior, intent
Externí odkaz:
https://doaj.org/article/2e4f64b2ef8844b799772d4ea092c11e
Autor:
Laísa Quadros Barsé, Agnes Ulfig, Marharyta Varatnitskaya, Melissa Vázquez-Hernández, Jihyun Yoo, Astrid M. Imann, Natalie Lupilov, Marina Fischer, Katja Becker, Julia E. Bandow, Lars I. Leichert
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT While highly effective at killing Gram-positive bacteria, auranofin lacks significant activity against Gram-negative species for reasons that largely remain unclear. Here, we aimed to elucidate the molecular mechanisms underlying the low sus
Externí odkaz:
https://doaj.org/article/6d64110ca5a545e0973e4299cde67a46
Autor:
Sabrina Baldofski, Sarah-Lena Klemm, Elisabeth Kohls, Sophia M. E. Mueller, Stephanie Bauer, Katja Becker, Silke Diestelkamp, Heike Eschenbeck, Alisa Hiery, Michael Kaess, Julian Koenig, Laya Lehner, Markus Moessner, Rainer Thomasius, Christine Rummel-Kluge
Publikováno v:
Frontiers in Public Health, Vol 11 (2024)
BackgroundNon-participation in mental health studies is an under-explored but very important topic. Investigating reasons for non-participation holds promise for the planning of future study designs and recruitment strategies. This study aimed at inv
Externí odkaz:
https://doaj.org/article/a6055396526040049571ce7a902224d7
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-14 (2022)
Crystallographic and biochemical characterization of Leishmania donovani Glucose 6-Phosphate Dehydrogenase (LdG6PD) containing the complete N-terminal domain reveal its role in LdG6PD tetramerization and substrate binding.
Externí odkaz:
https://doaj.org/article/fdd5343d42f34216b950a077bae05ada
Autor:
Lea Teresa Jendreizik, Christopher Hautmann, Elena von Wirth, Christina Dose, Ann-Kathrin Thöne, Anne-Katrin Treier, Tobias Banaschewski, Katja Becker, Daniel Brandeis, Julia Geissler, Johannes Hebebrand, Sarah Hohmann, Martin Holtmann, Michael Huss, Thomas Jans, Anna Kaiser, Sabina Millenet, Luise Poustka, Priska Schneider, Manfred Döpfner
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 16, Iss 1, Pp 1-14 (2022)
Abstract Background Children experiencing unfavorable family circumstances have an increased risk of developing externalizing symptoms. The present study examines the direct, indirect and total effects of family adversity, parental psychopathology, a
Externí odkaz:
https://doaj.org/article/a27f2c36a59e40c19e5da19ca6d9bb06
Autor:
Jana Samarin, Piotr Fabrowski, Roman Kurilov, Hana Nuskova, Johanna Hummel-Eisenbeiss, Hannelore Pink, Nan Li, Vivienn Weru, Hamed Alborzinia, Umut Yildiz, Laura Grob, Minerva Taubert, Marie Czech, Michael Morgen, Christina Brandstädter, Katja Becker, Lianghao Mao, Ashok Kumar Jayavelu, Angela Goncalves, Ulrike Uhrig, Jeanette Seiler, Yanhong Lyu, Sven Diederichs, Ursula Klingmüller, Martina Muckenthaler, Annette Kopp-Schneider, Aurelio Teleman, Aubry K. Miller, Nikolas Gunkel
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102639- (2023)
Despite a strong rationale for why cancer cells are susceptible to redox-targeting drugs, such drugs often face tumor resistance or dose-limiting toxicity in preclinical and clinical studies. An important reason is the lack of specific biomarkers to
Externí odkaz:
https://doaj.org/article/43f98fcf2a844645aeeecc65e57523ec
Autor:
Clara Marie Nittel, Frederike Dobelke, Jens König, Martin Konrad, Katja Becker, Inge Kamp-Becker, Stefanie Weber, for the NEOCYST consortium
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
This review investigates the association between neurodevelopmental disorders (NDD) and variations of the gene HNF1B. Heterozygous intragenetic mutations or heterozygous gene deletions (17q12 microdeletion syndrome) of HNF1B are the cause of a multi-
Externí odkaz:
https://doaj.org/article/97bae72d1db142af9d0623291bbd0627
Autor:
Viktor A. Zapol’skii, Isabell Berneburg, Ursula Bilitewski, Melissa Dillenberger, Katja Becker, Stefan Jungwirth, Aditya Shekhar, Bastian Krueger, Dieter E. Kaufmann
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 18, Iss 1, Pp 524-532 (2022)
A series of 26 novel 1-(7-chloroquinolin-4-yl)-4-nitro-1H-pyrazoles bearing a dichloromethyl and an amino or thio moiety at C3 and C5 has been prepared in yields up to 72% from the reaction of 1,1-bisazolyl-, 1-azolyl-1-amino-, and 1-thioperchloro-2-
Externí odkaz:
https://doaj.org/article/ba8e7aa5d9c0460badd51c998a8e57e5
Autor:
Jan G. Felber, Lena Poczka, Karoline C. Scholzen, Lukas Zeisel, Martin S. Maier, Sander Busker, Ulrike Theisen, Christina Brandstädter, Katja Becker, Elias S. J. Arnér, Julia Thorn-Seshold, Oliver Thorn-Seshold
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Cyclic five-membered disulfides (1,2-dithiolanes) have been reported either as nonspecific redox motifs, or as highly specific cellular probes for thioredoxin reductase (TrxR). Here the authors show that 1,2-dithiolane probes are nonspecifically redu
Externí odkaz:
https://doaj.org/article/d91e7f3ce64641b1a587ffd99090ce7f
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 87-95 (2022)
Plasmoredoxin is a 22 kDa thiol–disulfide oxidoreductase involved in cellular redox regulatory processes and antioxidant defense. The 1.6 Å structure of the protein, solved via X-ray crystallography, adopts a modified thioredoxin fold. The s
Externí odkaz:
https://doaj.org/article/4f8d7ba0d9d64a5fb094fe02f1f40fec