Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation

Autor: Flávio P. Veras, Gabriel A. Publio, Bruno M. Melo, Douglas S. Prado, Thainá Norbiato, Nerry T. Cecilio, Carlos Hiroki, Luis Eduardo A. Damasceno, Rebecca Jung, Juliana E. Toller-Kawahisa, Timna V. Martins, Stella F. Assunção, Diogenes Lima, Marcia G. Alves, Gabriel V. Vieira, Lucas A. Tavares, Ana L.R. Alves-Rezende, Susanne H. Karbach, Helder I. Nakaya, Thiago M. Cunha, Cacilda S. Souza, Fernando Q. Cunha, Katiuchia U. Sales, Ari Waisman, José C. Alves-Filho

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Psoriasis is an inflammatory skin disease characterized by keratinocyte proliferation and inflammatory cell infiltration induced by IL-17. However, the molecular mechanism through which IL-17 signaling in keratinocytes triggers skin inflammation rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc02df5b3f8e0c505c0f4f0c80a9a4d3
https://doi.org/10.1016/j.celrep.2022.111897