Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Katinka, Döhner"'
Autor:
Linda Grosche, Katinka Döhner, Alexandra Düthorn, Ana Hickford-Martinez, Alexander Steinkasserer, Beate Sodeik
Publikováno v:
Bio-Protocol, Vol 9, Iss 23 (2019)
Given the endemic seroprevalence of herpes simplex viruses (HSV), its associated human diseases, and the emergence of acyclovir-resistant strains, there is a continuous need for better antiviral therapies. Towards this aim, identifying mechanistic de
Externí odkaz:
https://doaj.org/article/175faf5fd78643d399703d7314031fb9
Autor:
Katinka Döhner, Ana Ramos-Nascimento, Dagmara Bialy, Fenja Anderson, Ana Hickford-Martinez, Franziska Rother, Thalea Koithan, Kathrin Rudolph, Anna Buch, Ute Prank, Anne Binz, Stefanie Hügel, Robert Jan Lebbink, Rob C Hoeben, Enno Hartmann, Michael Bader, Rudolf Bauerfeind, Beate Sodeik
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006823 (2018)
Herpesviruses are large DNA viruses which depend on many nuclear functions, and therefore on host transport factors to ensure specific nuclear import of viral and host components. While some import cargoes bind directly to certain transport factors,
Externí odkaz:
https://doaj.org/article/a57692e99186492db7bba0af26e5ad8d
Autor:
Anna Buch, Oliver Müller, Lyudmila Ivanova, Katinka Döhner, Dagmara Bialy, Jens B Bosse, Anja Pohlmann, Anne Binz, Maike Hegemann, Claus-Henning Nagel, Martin Koltzenburg, Abel Viejo-Borbolla, Bodo Rosenhahn, Rudolf Bauerfeind, Beate Sodeik
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006813 (2017)
Upon reactivation from latency and during lytic infections in neurons, alphaherpesviruses assemble cytosolic capsids, capsids associated with enveloping membranes, and transport vesicles harboring fully enveloped capsids. It is debated whether capsid
Externí odkaz:
https://doaj.org/article/7853ec5c48814a7b820f749a27354cd0
Autor:
Francisco J. Zapatero-Belinchón, Erik Dietzel, Olga Dolnik, Katinka Döhner, Rui Costa, Barbara Hertel, Barbora Veselkova, Jared Kirui, Anneke Klintworth, Michael P. Manns, Stefan Pöhlmann, Thomas Pietschmann, Thomas Krey, Sandra Ciesek, Gisa Gerold, Beate Sodeik, Stephan Becker, Thomas von Hahn
Publikováno v:
Viruses, Vol 11, Iss 3, p 275 (2019)
Filoviruses infect a wide range of cell types with the exception of lymphocytes. The intracellular proteins cathepsin B and L, two-pore channel 1 and 2, and bona fide receptor Niemann–Pick Disease C1 (NPC1) are essential for the endosomal phase of
Externí odkaz:
https://doaj.org/article/09e97d310df645fc8c25124376b4d0a3
Autor:
Isabel Veloso Alves Pereira, Bettina Buchmann, Lisa Sandmann, Kathrin Sprinzl, Verena Schlaphoff, Katinka Döhner, Florian Vondran, Christoph Sarrazin, Michael P Manns, Cláudia Pinto Marques Souza de Oliveira, Beate Sodeik, Sandra Ciesek, Thomas von Hahn
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117152 (2015)
The sodium-taurocholate cotransporting polypeptide (NTCP) is both a key bile acid (BA) transporter mediating uptake of BA into hepatocytes and an essential receptor for hepatitis B virus (HBV) and hepatitis D virus (HDV). In this study we aimed to ch
Externí odkaz:
https://doaj.org/article/3cba6396885a4f29bfcfe777bdb7a6e9
Publikováno v:
Current opinion in virology. 50
Starting a herpesviral infection is a steeplechase across membranes, cytosol, and nuclear envelopes and against antiviral defence mechanisms. Here, we highlight recent insights on capsid stabilization at the portals during assembly, early capsid-host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72f77ad7de3fb7482f1cb3f9f908548f
https://pubmed.ncbi.nlm.nih.gov/34464845
https://pubmed.ncbi.nlm.nih.gov/34464845
Autor:
Vânia Passos, Gunther Hartmann, Carlo Fischer, Christine Goffinet, Christiane Schüler, Fangfang Chen, Fabian Pott, Thomas Zillinger, Jan Felix Drexler, Sergej Franz, Frank Pessler, Sandra Dapa, Katinka Döhner, Graham Simmons, Beate Sodeik, Saskia Stenzel
Interferon-induced transmembrane (IFITM) proteins restrict infection by enveloped viruses through interfering with membrane fusion and virion internalisation. The role of IFITM proteins during alphaviral infection of human cells and viral counteracti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6645cc7d51b8fc3aa706e0375ea3d3b6
https://doi.org/10.1101/2020.09.11.292946
https://doi.org/10.1101/2020.09.11.292946
Autor:
Sangar Srivaratharajan, Antonio Alcami, Abel Viejo-Borbolla, Katinka Döhner, Alberto Domingo López-Muñoz, Beate Sodeik, Birgit Ritter, Alberto Rastrojo, Akshay Dhingra, Claus-Henning Nagel, Kai A. Kropp, Rocío Martín, Julia S. Czechowicz
Publikováno v:
Journal of Virology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Herpes simplex virus 2 (HSV-2) is a prevalent human pathogen that establishes lifelong latency in neurons of the peripheral nervous system. Colonization of neurons is required for HSV-2 persistence and pathogenesis. The viral and cellular factors req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca4c1be83fa511e0a9c6b0fb529a0dc
https://pubmed.ncbi.nlm.nih.gov/32669337
https://pubmed.ncbi.nlm.nih.gov/32669337
Autor:
Aparna Ponnurangam, Carina Elsner, Gunther Hartmann, Aurélie Ducroux, Daniel Todt, Katinka Döhner, Beate Sodeik, Pia-Katharina Larsen, Thomas Zillinger, Shuting Xu, Julia Kazmierski, Jenny Jansen, Angelina Malassa, Christine Goffinet, Winfried Barchet, Ulrich Kalinke, Eike Steinmann, Nils Kriedemann
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
United States
United States
Significance Whether HIV-1 infection triggers cGAS-mediated immune responses in CD4+ T cells remains debated. It is important to investigate to which extent HIV-1–infected T cells contribute to IFN production and expression of antiviral interferon-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd14b4aacf4b2b82da7ee1f4675eadc
https://www.ncbi.nlm.nih.gov/pubmed/32709741
https://www.ncbi.nlm.nih.gov/pubmed/32709741
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44177 (2012)
To analyze the subcellular trafficking of herpesvirus capsids, the small capsid protein has been labeled with different fluorescent proteins. Here, we analyzed the infectivity of several HSV1(17(+)) strains in which the N-terminal region of the non-e
Externí odkaz:
https://doaj.org/article/da6205618c52485b82a16495e0e3252d