Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Katina Lazarow"'
Autor:
Harsha V. Renikunta, Katina Lazarow, Yiqi Gong, Praphulla Chandra Shukla, Vanasa Nageswaran, Hector Giral, Adelheid Kratzer, Lennart Opitz, Felix B. Engel, Arash Haghikia, Sarah Costantino, Francesco Paneni, Jens Peter von Kries, Katrin Streckfuss-Bömeke, Ulf Landmesser, Philipp Jakob
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106593- (2023)
Summary: Ischemic cardiomyopathy, driven by loss of cardiomyocytes and inadequate proliferative response, persists to be a major global health problem. Using a functional high-throughput screening, we assessed differential proliferative potential of
Externí odkaz:
https://doaj.org/article/0397c180ca2842079b4aa0e59e2381c0
Autor:
Florian Ullrich, Sandy Blin, Katina Lazarow, Tony Daubitz, Jens Peter von Kries, Thomas J Jentsch
Publikováno v:
eLife, Vol 8 (2019)
Acid-sensing ion channels have important functions in physiology and pathology, but the molecular composition of acid-activated chloride channels had remained unclear. We now used a genome-wide siRNA screen to molecularly identify the widely expresse
Externí odkaz:
https://doaj.org/article/b4e93c9d6cbd4a358027e742c7171744
Autor:
Alessandro Dema, Dörte Faust, Katina Lazarow, Marc Wippich, Martin Neuenschwander, Kerstin Zühlke, Andrea Geelhaar, Tamara Pallien, Eileen Hallscheidt, Jenny Eichhorst, Burkhard Wiesner, Hana Černecká, Oliver Popp, Philipp Mertins, Gunnar Dittmar, Jens Peter von Kries, Enno Klussmann
Publikováno v:
Cells, Vol 9, Iss 3, p 673 (2020)
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface of the cells and stimula
Externí odkaz:
https://doaj.org/article/2e53df9d47594aa78197c2dae41ffcc8
TSG101 associates with PARP1 and is essential for PARylation and DNA damage-induced NF-κB activation
Autor:
Ahmet Bugra Tufan, Katina Lazarow, Marina Kolesnichenko, Anje Sporbert, Jens Peter von Kries, Claus Scheidereit
SUMMARYIn a genome-wide screening for components of the dsDNA-break-induced IKK-NF-κB pathway we identified scores of regulators, including tumor susceptibility protein TSG101. TSG101 is essential for DNA damage-induced formation of cellular poly(AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b28615c4b4e967f73c3970d2df10932
http://edoc.mdc-berlin.de/22119/1/22119oa.pdf
http://edoc.mdc-berlin.de/22119/1/22119oa.pdf
Autor:
Ahmet Buğra Tufan, Katina Lazarow, Marina Kolesnichenko, Anje Sporbert, Jens Peter von Kries, Claus Scheidereit
Publikováno v:
The EMBO Journal. 41
Autor:
Dörte Faust, Philipp Mertins, Enno Klussmann, Jens Peter von Kries, Oliver Popp, Martin Neuenschwander, Jenny Eichhorst, Burkhard Wiesner, Katina Lazarow, Hana Černecká, Kerstin Zühlke, Marc Wippich, Tamara Pallien, Gunnar Dittmar, Alessandro Dema, Eileen Hallscheidt, Andrea Geelhaar
Publikováno v:
Cells
Cells, Vol 9, Iss 3, p 673 (2020)
Volume 9
Issue 3
Cells, Vol 9, Iss 3, p 673 (2020)
Volume 9
Issue 3
Arginine-vasopressin (AVP) facilitates water reabsorption in renal collecting duct principal cells through regulation of the water channel aquaporin-2 (AQP2). The hormone binds to vasopressin V2 receptors (V2R) on the surface of the cells and stimula
Autor:
Katina Lazarow, Upendra Rao Anumala, Jo Waaler, Peter Lindemann, Alexander G. Majouga, Lari Lehtiö, Ezeogo Obaji, Alexander Ignatev, Sergey V. Leonov, Stefan Krauss, Marc Nazaré, Petter Angell Olsen, Y. Nkizinkiko, Sudarshan Murthy, Jens Peter von Kries
Publikováno v:
Journal of Medicinal Chemistry. 60:10013-10025
A structure-guided hybridization approach using two privileged substructures gave instant access to a new series of tankyrase inhibitors. The identified inhibitor 16 displays high target affinity on tankyrase 1 and 2 with biochemical and cellular IC5
Autor:
Guojun Yang, Zsuzsanna Izsvák, Zoltán Ivics, Katina Lazarow, Ding-Qin Tang, Reinhard Kunze, Csaba Miskey, Mingbing Zhou, Hui Hu
Publikováno v:
Molecular Phylogenetics and Evolution. 109:367-374
The moso bamboo genome contains the two structurally intact and thus potentially functional mariner-like elements Ppmar1 and Ppmar2. Both elements contain perfect terminal inverted repeats (TIRs) and a full-length intact transposase gene. Here we inv
Autor:
Thomas J. Jentsch, Tobias Stauber, Florian Ullrich, Darius Lutter, Jens Peter von Kries, Felizia K. Voss, Nancy Mah, Jonas Münch, Katina Lazarow, Miguel A. Andrade-Navarro
Publikováno v:
Science
One Swell Ion Channel When mammalian cells are faced with osmotic challenges, they need to swell or shrink. The molecular characterization of the volume-regulated anion channel (VRAC) remains unknown, although many candidate proteins have been propos