Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Katie R. Barnes"'
Autor:
Ralph Weissleder, Lee Josephson, Hushan Yuan, Adam Smith, Lewis C. Cantley, Katie R. Barnes, Joseph Blois, Fred Reynolds
Publikováno v:
Bioconjugate Chemistry. 19:130-137
Here, we report on NBD-Wm, a fluorescent wortmannin (Wm) probe that maintains the bioactivity of Wm as an inhibitor of PI3 kinase and as an antiproliferative agent. The attachment of the NBD fluorochrome permits NBD-Wm in cells to be monitored by NBD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1aa7b310d8ae5d650e854de1cca21d
https://doi.org/10.1021/bc7002204
https://doi.org/10.1021/bc7002204
Publikováno v:
Chemistry & Biology. 14(3):321-328
SummaryWortmannin (Wm), a steroid-like molecule of 428.4 Da, appears to be unstable in biological fluids (apparent chemical instability), yet it exhibits an antiproliferative activity in assays employing a 48 hr incubation period (prolonged bioactivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d28056074799dd1b85ad9bf511c9f95
Autor:
Carolyn C. Woodroofe, Stephen J. Lippard, Rafik Masalha, Christopher J. Frederickson, Katie R. Barnes
Publikováno v:
Chemistry & Biology. 11(12):1659-1666
SummaryEsterification of fluorescent biosensors is a common strategy used to trap probes within the cell. Zinpyr-1 (ZP1) is a fluorescein-based bright fluorescent sensor for divalent zinc that is cell permeable without prior modification. We describe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fc72416400749bc6f16895eb2bebdd
Autor:
Sumitra Mukhopadhyay, Stephen J. Lippard, Sarah M. Short, Ariel Haskel, Katie R. Barnes, Carmen M. Barnes
The integrins alpha vbeta3 and alpha vbeta5 and the membrane-spanning surface protein aminopeptidase N (APN) are highly expressed in tumor-induced angiogenesis, making them attractive targets for therapeutic intervention. Both integrins and APN recog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dd97b045c5a11e761ef56724729f45
https://europepmc.org/articles/PMC2505196/
https://europepmc.org/articles/PMC2505196/
Autor:
Katie R, Barnes, Stephen J, Lippard
Publikováno v:
Metal ions in biological systems. 42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4968e3126b55d773151e045da0f04210
https://pubmed.ncbi.nlm.nih.gov/15206102
https://pubmed.ncbi.nlm.nih.gov/15206102
Publikováno v:
Chemistrybiology. 11(4)
Several estrogen-tethered platinum(IV) complexes were prepared and characterized by ESI-MS and (1)H NMR spectroscopy. Their design was inspired by the observation that estrogen receptor-positive cells exposed to the hormone are sensitized to cisplati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce2aac318c4d20799e1bb633d41a5ee
https://pubmed.ncbi.nlm.nih.gov/15123250
https://pubmed.ncbi.nlm.nih.gov/15123250
Autor:
Katie R. Barnes, Joseph Blois, Adam Smith, Hushan Yuan, Fred Reynolds, Ralph Weissleder, Lewis C. Cantley, Lee Josephson
Publikováno v:
Bioconjugate Chemistry; Dec2007, Vol. 19 Issue 1, p130-137, 8p