Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katie R Stockdale"'
Autor:
William H Thiel, Thomas Bair, Andrew S Peek, Xiuying Liu, Justin Dassie, Katie R Stockdale, Mark A Behlke, Francis J Miller, Paloma H Giangrande
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43836 (2012)
The broad applicability of RNA aptamers as cell-specific delivery tools for therapeutic reagents depends on the ability to identify aptamer sequences that selectively access the cytoplasm of distinct cell types. Towards this end, we have developed a
Externí odkaz:
https://doaj.org/article/89e7a8b78bce46dea63ccda58900cb55
Autor:
James O. McNamara, Alissa M. Rothman, Kristina W. Thiel, Frank J. Hernandez, Justin P. Dassie, Paloma H. Giangrande, William H. Thiel, Xiuying Liu, Luiza I. Hernandez, Katie R. Stockdale
Publikováno v:
Nucleic Acids Research
Human epidermal growth factor receptor 2 (HER2) expression in breast cancer is associated with an aggressive phenotype and poor prognosis, making it an appealing therapeutic target. Trastuzumab, an HER2 antibody-based inhibitor, is currently the lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b494595c1ea2a34ab7e55eb70f246caa
https://doi.org/10.1093/nar/gks294
https://doi.org/10.1093/nar/gks294
Autor:
Bin Gu, Mark A. Behlke, Kishore Nanapaneni, Paloma H. Giangrande, Frank J. Hernandez, James O. McNamara, Andrew S. Peek, Todd E. Scheetz, Katie R. Stockdale, Yang Zhong Huang, Thomas B. Bair
Many cell surface signaling receptors, such as the neurotrophin receptor, TrkB, have emerged as potential therapeutic targets for diverse diseases. Reduced activation of TrkB in particular is thought to contribute to neurodegenerative diseases. Unfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604fb747e4851645e8fb400670465306
https://europepmc.org/articles/PMC3463223/
https://europepmc.org/articles/PMC3463223/
Autor:
Alexander R. Horswill, Lingyan Huang, Mark A. Behlke, Frank J. Hernandez, Katie R. Stockdale, James O. McNamara
Publikováno v:
Nucleic acid therapeutics. 22(1)
Artificial RNA reagents such as small interfering RNAs (siRNAs) and aptamers often must be chemically modified for optimal effectiveness in environments that include ribonucleases. Mycoplasmas are common bacterial contaminants of mammalian cell cultu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac3a9113b5c1c3fa804414243450407
https://pubmed.ncbi.nlm.nih.gov/22229275
https://pubmed.ncbi.nlm.nih.gov/22229275
Autor:
Thomas B. Bair, Paloma H. Giangrande, Francis J. Miller, Mark A. Behlke, Katie R. Stockdale, Xiuying Liu, William H. Thiel, Justin P. Dassie, Andrew S. Peek
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43836 (2012)
PLoS ONE
PLoS ONE
Background The broad applicability of RNA aptamers as cell-specific delivery tools for therapeutic reagents depends on the ability to identify aptamer sequences that selectively access the cytoplasm of distinct cell types. Towards this end, we have d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47054703eb727a21a4b895e936513402
http://europepmc.org/articles/PMC3433472?pdf=render
http://europepmc.org/articles/PMC3433472?pdf=render
Autor:
Xiuying Liu, Justin P. Dassie, Ryan M. Whitaker, Paloma H. Giangrande, James O. McNamara, Anton P. McCaffrey, Kristina W. Thiel, David K. Meyerholz, Katie R. Stockdale, Gregory S. Thomas
Publikováno v:
Nature Biotechnology
Prostate cancer cells expressing prostate-specific membrane antigen (PSMA) have been targeted with RNA aptamer-small interfering (si)RNA chimeras, but therapeutic efficacy in vivo was demonstrated only with intratumoral injection. Clinical translatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a07a410110d6416f5eff8a2ed70a32
https://pubmed.ncbi.nlm.nih.gov/19701187
https://pubmed.ncbi.nlm.nih.gov/19701187