Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Katie Pfeffer"'
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Abstract PD2-04: Preclinical development of CodaLytic™, a codon-modified influenza virus, as a novel virotherapeutic agent for breast cancer immunotherapy
Autor: Marcin Stawowczyk, Yiwen Zhao, Katie Pfeffer, Juliana Tafrova, James Rodriguez, Chen Yang, Nusrat Jahan, Sybil A. Tasker, Steffen Mueller, J. Robert Coleman, Johanna K. Kaufmann
Publikováno v: Cancer Research. 83:PD2-04
Multiple species of oncolytic viruses (OVs) have been shown to modulate the tumor microenvironment (TME) by increasing immune cell infiltration and activating stimulatory immune responses, leading to the induction of a tumor-specific immune response.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::088baa19794622b06bf2217a4a780822
https://doi.org/10.1158/1538-7445.sabcs22-pd2-04
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Abstract 689: The codon-modified influenza virus CodaLytic™rescues immunostimulatory activity and anti-tumor efficacy in PD-1-refractory tumor models
Autor: Yiwen Zhao, Nusrat Jahan, Marcin Stawowczyk, Katie Pfeffer, Juliana Tafrova, James Rodriguez, Chen Yang, Sybil A. Tasker, Steffen Mueller, J. Robert Coleman, Johanna K. Kaufmann
Publikováno v: Cancer Research. 83:689-689
Multiple oncolytic viruses have been shown to induce various beneficial changes in the tumor microenvironment (TME), which ultimately support induction of anti-tumor immune responses. We have previously demonstrated that CodaLytic, a codon-modified i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f34f438c813fa91796a4614e608dd8e9
https://doi.org/10.1158/1538-7445.am2023-689
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747 CodaLytic™, a novel codon-pair deoptimized influenza virus creates an immune-stimulatory tumor microenvironment leading to monotherapy efficacy in a preclinical model of breast cancer
Autor: Juliana Tafrova, Steffen Mueller, Sybil A. Tasker, J. Robert Coleman, Marcin Stawowczyk, Katie Pfeffer, Charles B. Stauft, Johanna Kaufmann, Anna Kushnir
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundOncolytic viruses (OVs) of multiple species have been demonstrated to induce beneficial changes in the tumor microenvironment (TME), increasing immune cell infiltration and activating stimulatory immune responses, which ultimately support i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba562964dad1b78b6cee1c8783ff8258
https://doaj.org/article/48c486fc5a694640a8100f05390d164c
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