Repurposing CRISPR-Cas13 systems for robust mRNA trans-splicing

Autor: David N. Fiflis, Nicolas A. Rey, Harshitha Venugopal-Lavanya, Beatrice Sewell, Aaron Mitchell-Dick, Katie N. Clements, Sydney Milo, Abigail R. Benkert, Alan Rosales, Sophia Fergione, Aravind Asokan

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Type VI CRISPR enzymes have been developed as programmable RNA-guided Cas proteins for eukaryotic RNA editing. Notably, Cas13 has been utilized for site-targeted single base edits, demethylation, RNA cleavage or knockdown and alternative spl

Externí odkaz: https://doaj.org/article/4a9e799fbf1b4f619012e055594df9cf

The mechanisms shaping CA2 pyramidal neuron action potential bursting induced by muscarinic acetylcholine receptor activation

Autor: Ludivine Therreau, Katie N Clements, Vincent Robert, F. Javier Bernardo-Garcia, M. Felicia Davatolhagh, Rebecca A. Piskorowski, Vivien Chevaleyre

Publikováno v: Journal of General Physiology
Journal of General Physiology, Rockefeller University Press, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩
The Journal of General Physiology
Journal of General Physiology, 2020, 152 (4), pp.e201912462. ⟨10.1085/jgp.201912462⟩

Robert et al. reveal that muscarinic receptor activation causes hippocampal CA2 pyramidal neurons to depolarize and fire bursts of action potentials. The properties of these bursts are regulated by synaptic inputs, as well as T-type calcium channels,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a811c3893538eacc90d134b4e8af484
https://www.hal.inserm.fr/inserm-02771945/file/jgp_201912462.pdf

25th Annual Computational Neuroscience Meeting: CNS-2016

Autor: Stefan Rotter, Ryan T. Philips, Katie N Clements, Sumin Jo, Giulia Lia Beatrice Spampinato, Cornelia Denk, Florence I. Kleberg, Shang Mu, Kazuyuki Aihara, Valerie Voon, Roman Martel, Tom Tetzlaff, Mir Jeong, Luziwei Leng, Padraig Gleeson, Seungjun Lee, Nathaniel N. Urban, John D. Murray, Sung-beom Lee, Martin Giese Giese, Yun Seo Choi, Yuri Dabaghian, Hoon-Hee Kim, Laurent Badel, Greg J. Stephens, Veli Baysal, Mahmut Ozer, William W. Lytton, Peter De Weerd, Huiwen Ju, Martin Zapotocky, Young-Ah Rho, Peter Andras, Dennis Goldschmidt, Shivakeshavan Ratnadurai-Giridharan, Charles M. Welzig, Seung Kee Han, Alex Fornito, Tae Kim, Cheng Cheng, Sang Wan Lee, Hannah Choi, Yuzhe Wang, Benjamin Torben-Nielsen, Felix Goetze, Mohammad Javad Faraji, Poramate Manoonpong, Andrew Davison, Lukas Plogmacher, Pangyu Joo, Ho Ka Chan, Julia M. Warburton, Francisco B. Rodriguez, Pyeong Soo Kim, Daniel Saska, Seongkyun Kim, Sergey N. Markin, H. Sebastian Seung, Anders M. Dale, Maria Luisa Saggio, Timothy B Esler, Andreas Spiegler, Renato Duarte, In-Seob Shin, Mounir Maouene, Dima Rinberg, Dae Eun Kim, Andrey Babichev, Andrew R. Gallimore, Anna Levina, Heidi I.L. Jacobs, Maria A. G. Witek, Jeanette Hellgren Kotaleski, Kelly Toppin, Choongseok Park, Achim Schweikard, Wulfram Gerstner, Jeffrey C. Smith, N. Alex Cayco Gajic, Gaby Maimon, Michael C. Ridding, Luca Pollonini, Julia Ramsey, Khaldoun C. Hamade, Kerstin Preuschoff, Changju Lee, Kevin C. Daly, Dong-Uk Hwang, Michal Zochowski, Taegyo Kim, Benjamin A. Suter, Pamela Osborn Popp, Joseph T. Lizier, Stan C. A. M. Gielen, Oh-Hyeon Choung, Mikail Rubinov, Jaehyun Soh, Michael Breakspear, Daniel Soundry, Stephen V. Gliske, Shin Ishii, Klas H. Pettersen, Su Hyun Kim, Hamza Giaffar, Brenton Hordacre, Joonwon Lee, Nick Mellen, Andrea Ferrario, Boris Marin, Thiago Mosqueiro, Antonio Parziale, Fred Wolf, Sara J. Aton, Karlheinz Meier, Juhyoung Ryu, Anna Devor, Yoriko Yamamura, Daniel Keller, Jerald D. Kralik, Glenn T. Lines, Morten L. Kringelbach, Sergio Verduzco-Flores, Jung Hoon Lee, Claus-Christian Hilgetag, Richard Veale, Felix Klanner, Coralie Fouquet, Matthias Scheutz, Ji Won Yeon, Johanna Senk, Michael A. Buice, Wenhao Zhang, Do-won Lee, Irene Elices, Atthaphon Viriyopase, Kaoutar Skiker, Moritz Helias, Lucia Marucci, S. Nader Rasuli, Weiliang Chen, Janos Vörös, Sharon M. Crook, Il Memming Park, Hojeong Kim, Frédéric Chavane, Joaquín J. Torres, Alexander Seeholzer, Hyoungkyu Kim, Martin F. Strube-Bloss, V. Srinivasa Chakravarthy, Sang Beom Jun, Tim Kunze, Justin Blackwell, Youngsoo Kim, Nam Jung, Volker Steuber, Rosa Senatore, Timm Lochmann, Christophe Bernar, Csaba Forró, Ole A. Andreassen, Jeroen J. Briaire, Hokto Kazama, E.B. Muller, Tae Ho Lee, Dahui Wang, Christian G. Fink, Axel Hutt, Alex Koulakov, Emili Balaguer-Ballester, Michael R. Ibbotson, Richard C. Gerkin, Ritchie E. Brown, Jianzhong Su, Valentin Dragoi, Samual P. Bradle, Alexandra H. Seidenstein, Mihai A. Petrovici, Johan H. M. Frijns, Leonid L. Rubchinsky, Jeungmin Lee, B. Pragathi Priyadharsini, Raoul-Martin Memmesheimer, Kwangyeol Baek, Everton J. Agnes, Thomas Knösche, Michael Wibral, Mark Cook, Henry Kennedy, Laurel S. Morris, Silvan F. Siep, Yunliang Zang, Terrence J. Sejnowski, Neil Davey, Olga Sourina, Eric Lowet, Francesco Tamagnini, Changsong Zhou, Sangsup Yoon, Karthik Soman, Chung Ching Cheung, Gaute T. Einevoll, Daeseob Lim, James T. McKenna, Yoonsuck Choe, Jonathan W. Pillow, Andre Peterson, Chris Rennie, Ryan S. Phillips, Levin Kuhlmann, Won Sup Kim, Terence D. Sanger, Anitha Pasupathy, Abdorreza Goodarzinick, Kelly Shen, Maria Psarrou, Luca Cocchi, Michal Hadrava, Safura Rashid Shomali, Huei-Fang Yang, Julia Goncharenko, Matthew R. Bennett, Alain Trembleau, Woochul Choi, Hyun Jae Jang, Minjung Kim, Lucas Rudelt, James H. Howard, Aref Pariz, Le Anh Quang, Nicolas Brunel, M. D. Niry, Rosemary J. Menzies, Mads Hansen, Pablo Varona, George Zouridakis, Maurizio De Pittà, R. Angus Silver, Yves F. Widmer, Steven Shea, Heonsoo Lee, Adrián Ponce-Alvarez, Johannes Bill, Jimin Kim, Jaeson Jang, Yi-Yuan Tang, Hu He, Samuel A. Neymotin, Merav Stern, David B. Grayden, Kanishka Basnayake, D. Alistair Steyn-Ross, William Podlaski, Ji Hyun Bak, Haim Sompolinsky, Vignesh Muralidharan, Jan Benda, Steven J. Schiff, Christina M. Weaver, Ilya A. Rybak, Sacha J. van Albada, Alan Diamond, Hima Mehta, Thomas Nowotny, Sol Park, Soohyun Lee, Erik De Schutter, Krasimira Tsaneva-Atanasova, Joscha Liedtke, Bart Gips, Claudia Clopath, Marko Filipović, Hideaki Shimazaki, Paula Sanz-Leon, Min Song, Frances K. Skinner, Timothée Leleu, Abigail Morrison, Spase Petkoski, Viktor K. Jirsa, Jing Guang, Hyang Woon Lee, Ilhwan Choi, Marcel Stimberg et Olivier Marre, Eoon Hye Ji, Nicolangelo Iannella, Robert R. Kerr, Jeffery R. Wickens, Natalia Toporikova, Jae Woo Lee, Sora Ahn, William F Podlaski, Simon G. Sprecher, Xiao Jing Wang, X. Zhao, Gilad Silberberg, Taro Toyoizumi, Wondimu Teka, Eunji Jun, Sat Byul Seo, Liang Chen, Gordon M. G. Shepherd, Benjamin Lindner, Shawn D. Burton, Rongxiang Tang, Peter A. Robinson, K. Y. Michael Wong, John Rinzel, Felix Fung, Leonid Fedorov, James P. Roach, Juhee Kim, Penelope J. Kale, Sacha Jennifer van Albada, Angelo Marcelli, Amy Reyes, Gleb Bezgin, Jochen Triesch, Tatiana Kameneva, Ramon Reig, Shigeyuki Oba, Isao Nishikawa, Christoph Metzner, Salvador Dura-Bernal, Brandon A. Levy, Silvio Ionta, Chang Sub Kim, Christoph S. Herrmann, Simone Buttler, Robert J. Schmidt, Krešimir Josić, Alexandra Kruscha, Nicoladie D. Tam, William C. Stacey, Eric Shea-Brown, Daniel Šmít, Julien Vitay, Katharina Glomb, Phillip D. Chapman, Kevin L. Briggman, Luca Perotti, Jorge F. Mejias, Petr Marsalek, Malte J. Rasch, Zachary P. Kilpatrick, Won Hee Lee, Prantik Kundu, Baptiste Lefebvre, Gary Marsat, Ji-yong Lee, Jeonghun Baek, Ilja Bytschok, Walter Senn, Dongsung Huh, Jisung Wang, Matthieu Gilson, James Rankin, Sang-Hun Lee, Simon M. Vogt, Lisa M. Fenk, Leonardo L. Gollo, Mohammad Hovaidi Ardestani, Moira L. Steyn-Ross, Thomas H Miller, Akira Takashima, Tim P. Vogels, Guangsheng Liang, Vladislav Sekulić, Yale E. Cohen, Shaun L. Cloherty, Sung-Phil Kim, Christof Koch, Eunjin Hwang, Hyang Jung Lee, Ergin Yilmaz, Mark D. McDonnell, Quinton M. Skilling, Geir Halnes, Xu Yang, Patrick R. Hof, Criseida Zamora, Pik‑Yin Lai, Youngjo Song, Daniel T. Robb, Stephen Van Wert, Roberto Latorre, Udo A. Ernst, Luozheng Li, Tuomo Mäki-Marttunen, Henry Markram, Juraj Kukolja, Majid Nili Ahmadabadi, Yaroslav I. Molkov, Eli Shlizerman, B. Kahng, Kenji Doya, Viola Priesemann, Guido Klingbeil, Richard Spinney, Alejandro Tabas, Tatyana O. Sharpee, Matteo Cantarelli, Hae-Jeong Park, Matias I. Maturana, Min-Ho Song, Romesh G. Abeysuriya, Braden A. W. Brinkman, Laure Buhry, Seth A. Kiser, Fred Rieke, Claudia Bachmann, Roman Borisyuk, Fred H. Hamker, Shervin S. Parsi, David Stöckel, Philippa J. Karoly, Chungho Lee, Yixin Guo, Margriet J. van Gendt, Ben D. Fulcher, Jaehyung Kwon, Campbell McLauchlan, Stephanie E. Palmer, Catherine E. Davey, Bowon Kim, Sue-Hyun Lee, Pierre Yger, Jaeseung Jeong, Espen Hagen, Bruce P. Graham, Andy Edwards, Jordan Drew, Eric F. Clarke, Max Nolte, Robert W. McCarley, Oliver Breitwieser, Dorottya Cserpán, Yoon-Kyu Song, Peter Lakatos, Mark Roberts, Justin DeVito, Liam Paninski, Chaitanya Chintaluri, Jangsup Moon, David J. Kedziora, Yong Jeong, Jaejin Lee, Yuan Zaho, Petra Ritter, Veronika Koren, Bahar Moezzi, Gereon R. Fink, Ege T. Kavalali, G. Bard Ermentrout, Mingsha Zhang, William H. Barnett, Alexandra P. Chatzikalymniou, Danel Draguljić, Guang-Bin Huang, Jennifer I. Luebke, Patricia H. P. Tran, Timothy Rumbell, Woo-Sung Jung, André Rupp, Zhiheng Xu, Aslak Tveito, Bartosz Zurowski, Cliff C. Kerr, Adrian Quintana, Jaehwan Jahng, Johannes Schemmel, Eugene Lim, Manuel Schottdorf, Michael L. Hines, Haiping Huang, Ole Jensen, Jiao Yu, Chang-hyun Park, Dean R. Freestone, SueYeon Chung, Chris I. Baker, Ramakrishnan Iyer, Justas Birgiolas, Sophia Frangou, Yoshiko Tsuchimoto, Yong‑il Lee, Xiaochen Zhao, Jaroslav Hlinka, Markus Diesmann, Larry F. Abbott, Hansol Choi, Yuanyuan Mi, Hamish Meffin, Bahman Tahayori, Martin A. Giese, Nicolette Ognjanovski, Jiyoung Kang, Rufin Vogels, Peter Vuust, Dan D. Lee, Jyotika Bahuguna, Ramon Huerta, Youngjin Park, Brian H. Smith, Jens Wilting, Seonghyun Kim, Matias J. Palva, Hio-Been Han, Ji Sung Park, Yonatan I. Fishman, James A. Roberts, Sadra Sadeh, Haoqi Sun, Daniel K. Wójcik, Robert Merrison-Hort, Tim Vogels, Ingo Bojak, Kim van Dillen, Chang Zhao, Hyeonsu Lee, Klaus Obermayer, Zachary J. Harper, Pradeep Kuravi, Maximilian Schmidt, Katherine A. Holman, Harald Dermutz, Jeehyun Kwag, Minsu Yoo, Junichiro Yoshimoto, Jae Kyoung Kim, Suin Yu, Jae-Hwan Kang, Sabyasachi Shivkumar, Sergej O. Voronenko, Tosif Ahamed, Hugues Berry, Sakyasingha Dasgupta, Mitsuo Kawato, Natalie Schaworonkow, David Arroyo, Samuel Neymotin, Daniel Kepple, Arvind Kumar, René Richter, Gustavo Deco, Rafael Levi, Guang Ouyang, Micah M. Murray, László Demkó, Randy K. Kalkman, Hee-Sup Shin, Rajnish Ranjan, Yasunori Yamada, Alain Destexhe, Jon T. Brown, Jinseop S. Kim, Yann Sweeney, Stefan Mihalas, Hannah Bos, LieJune Shiau, Detlef Wegener, Júlia V. Gallinaro, Fabiano Baroni, Yuguo Yu, Younginha Jung, Xiaohan Lin, Michael W. Reimann, Hailin Ma, Jee Hyun Choi, Si Wu, Viviana Culmone, Sungho Hong, Leonard M. Sander, Mitchell R. Goldsworthy, Ad Aertsen, Seung Eun Maeng, Sewoong Lim, Se-Bum Paik, Sungwoo Ahn, Maria J. Schilstra, Sang-Min Park, Will Leahy, Alireza Valizadeh, P.M. Drysdale, Tyler Kekona, Frederick Beuth, Filipa dos Santos, Lisa Bohnenkamp, Rembrandt Bakker, Mikkel Wallentin, Sheng-Jun Wang, Anthony N. Burkitt, Anmo J. Kim, Jérémie Lefebvre, Katie A. Ferguson, Taro Tezuka, Jan Grewe, Fadi A. Issa, Hyeon-Man Baek, Karishma Chhabria, Kazumi Ohta, Elric Esposito, Seok-hyun Moon, Jan van der Eerden, Philipp Weidel, Zoltán Somogyvári, Alekhya Mandali

Publikováno v: BMC Neuroscience
BMC Neuroscience, 2016, 17 (S1), pp.54. ⟨10.1186/s12868-016-0283-6⟩

Table of contents A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::548d95ae446c300b09a1122a14de4e99