Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Katie M. Campbell"'
Autor:
Prabhat K. Purbey, Joowon Seo, Manash K. Paul, Keisuke S. Iwamoto, Allison E. Daly, An-Chieh Feng, Ameya S. Champhekar, Justin Langerman, Katie M. Campbell, Dörthe Schaue, William H. McBride, Steven M. Dubinett, Antoni Ribas, Stephen T. Smale, Philip O. Scumpia
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114289- (2024)
Summary: Type I interferon (IFN-I) and IFN-γ foster antitumor immunity by facilitating T cell responses. Paradoxically, IFNs may promote T cell exhaustion by activating immune checkpoints. The downstream regulators of these disparate responses are i
Externí odkaz:
https://doaj.org/article/1aacdb1bc8d04f2aac55bcac0e7d97b6
Autor:
Daniel G. Chen, Jingyi Xie, Jongchan Choi, Rachel H. Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Ben Solomon, Katie M. Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis L. Lanier, Philip J. Mease, Jason D. Goldman, Yapeng Su, James R. Heath
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113872- (2024)
Summary: Infection, autoimmunity, and cancer are principal human health challenges of the 21st century. Often regarded as distinct ends of the immunological spectrum, recent studies hint at potential overlap between these diseases. For example, infla
Externí odkaz:
https://doaj.org/article/66da9e46dc354e898aea61faa116e5ae
Autor:
Ameya Champhekar, Rachel Heymans, Justin Saco, Guillem Turon Font, Cynthia Gonzalez, Anne Gao, John Pham, June Lee, Ryan Maryoung, Egmidio Medina, Katie M. Campbell, Daniel Karin, David Austin, Robert Damioseaux, Antoni Ribas
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Interferon-gamma (IFNγ) exerts potent growth inhibitory effects on a wide range of cancer cells through unknown signaling pathways. We pursued complementary screening approaches to characterize the growth inhibition pathway. Meth
Externí odkaz:
https://doaj.org/article/cfb6bd2a7f124521a827711842f313d1
Autor:
Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L. Freshour, Zachary L. Skidmore, Huiming Xia, Joshua F. McMichael, Jason Kunisaki, Katie M. Campbell, Timothy Hung-Po Chen, Emily B. Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C. Chapman, Christopher A. Maher, Vivek Arora, Gavin P. Dunn, Ravindra Uppaluri, Ramaswamy Govindan, Obi L. Griffith, Malachi Griffith
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Analysing the regulatory consequences of mutations and splice variants at large scale in cancer requires efficient computational tools. Here, the authors develop RegTools, a software package that can identify splice-associated variants from large-sca
Externí odkaz:
https://doaj.org/article/a791b7f280e84d3d8c3cf984f3f564cd
Autor:
Ameya Champhekar, Rachel Heymans, Justin Saco, Guillem Turon Font, Cynthia Gonzalez, Anne Gao, John Pham, June Lee, Ryan Maryoung, Egmidio Medina, Katie M. Campbell, Daniel Karin, David Austin, Robert Damioseaux, Antoni Ribas
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/31d33bf8930943b2a8c59aa1564a8b7c
Autor:
Antoni Ribas, Alain Algazi, Paolo A. Ascierto, Marcus O. Butler, Sunandana Chandra, Michael Gordon, Leonel Hernandez-Aya, Donald Lawrence, Jose Lutzky, Wilson H. Miller, Katie M. Campbell, Bruno Delafont, Shannon Marshall, Nancy Mueller, Caroline Robert
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Immune checkpoints inhibitors or MAPK inhibitors are currently used as standard of care therapies for patients with advanced melanoma. Here the authors report a phase 1 clinical trial testing the anti-PD-L1 antibody durvalumab in combination with the
Externí odkaz:
https://doaj.org/article/2021304222154fa1af9d43a174d21c40
Autor:
Megan M. Richters, Huiming Xia, Katie M. Campbell, William E. Gillanders, Obi L. Griffith, Malachi Griffith
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-21 (2019)
Abstract Neoantigens are newly formed peptides created from somatic mutations that are capable of inducing tumor-specific T cell recognition. Recently, researchers and clinicians have leveraged next generation sequencing technologies to identify neoa
Externí odkaz:
https://doaj.org/article/1ba0106236d94549b59495df324a8b82
Autor:
Antoni Ribas, Alain Algazi, Paolo A. Ascierto, Marcus O. Butler, Sunandana Chandra, Michael Gordon, Leonel Hernandez-Aya, Donald Lawrence, Jose Lutzky, Wilson H. Miller, Katie M. Campbell, Bruno Delafont, Shannon Marshall, Nancy Mueller, Caroline Robert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/d43d6cb5eed04adbaa9c7c0324c11d5c
Autor:
Kilannin Krysiak, Arpad M Danos, Jason Saliba, Joshua F McMichael, Adam C Coffman, Susanna Kiwala, Erica K Barnell, Lana Sheta, Cameron J Grisdale, Lynzey Kujan, Shahil Pema, Jake Lever, Sarah Ridd, Nicholas C Spies, Veronica Andric, Andreea Chiorean, Damian T Rieke, Kaitlin A Clark, Caralyn Reisle, Ajay C Venigalla, Mark Evans, Payal Jani, Hideaki Takahashi, Avila Suda, Peter Horak, Deborah I Ritter, Xin Zhou, Benjamin J Ainscough, Sean Delong, Chimene Kesserwan, Mario Lamping, Haolin Shen, Alex R Marr, My H Hoang, Kartik Singhal, Mariam Khanfar, Brian V Li, Wan-Hsin Lin, Panieh Terraf, Laura B Corson, Yasser Salama, Katie M Campbell, Kirsten M Farncombe, Jianling Ji, Xiaonan Zhao, Xinjie Xu, Rashmi Kanagal-Shamanna, Ian King, Kelsy C Cotto, Zachary L Skidmore, Jason R Walker, Jinghui Zhang, Aleksandar Milosavljevic, Ronak Y Patel, Rachel H Giles, Raymond H Kim, Lynn M Schriml, Elaine R Mardis, Steven J M Jones, Gordana Raca, Shruti Rao, Subha Madhavan, Alex H Wagner, Malachi Griffith, Obi L Griffith
Publikováno v:
Nucleic Acids Research. 51:D1230-D1241
CIViC (Clinical Interpretation of Variants in Cancer; civicdb.org) is a crowd-sourced, public domain knowledgebase composed of literature-derived evidence characterizing the clinical utility of cancer variants. As clinical sequencing becomes more pre
Autor:
Antoni Ribas, Cristina Puig-Saus, Begoña Comin-Anduix, Jas Singh, Ignacio Baselga-Carretero, Ivan Perez-Garcilazo, Ameya S. Champhekar, Mildred Galvez, Justin D. Saco, Egmidio Medina, Katie M. Campbell, Daniel Karin, Davis Y. Torrejon, Gabriel Abril-Rodriguez
Supplemental Table 3: Differential gene expression analysis between B16 KO and WT tumors in vivo at day 6. Showing genes with q < 0.05 and log2FC > 1 or < -1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e80c04f0c12e19698320b399bff3a9
https://doi.org/10.1158/2767-9764.22545384.v1
https://doi.org/10.1158/2767-9764.22545384.v1