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Autor:
Chao Liu, Johan Peränen, Yun Wang, Mikko Airavaara, Barry J. Hoffer, Brandon K. Harvey, Doug B. Howard, Matt J. Chiocco, Shengyun Fang, Katie L. Zuchowski
Publikováno v:
Experimental Neurology. 225:104-113
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a secreted protein which reduces endoplasmic reticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. Intracortical delivery of recombinant MANF protein protects tissue