Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Katie L. Williams"'
Autor:
Amaya I Wolf, Krystyna Mozdzanowska, Katie L Williams, David Singer, Monique Richter, Ralf Hoffmann, Andrew J Caton, Laszlo Otvos, Jan Erikson
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28445 (2011)
The extracellular domain of the influenza A virus protein matrix protein 2 (M2e) is remarkably conserved between various human isolates and thus is a viable target antigen for a universal influenza vaccine. With the goal of inducing protection in mul
Externí odkaz:
https://doaj.org/article/f73533fac96b4b488c6d21521ca56604
Autor:
Eric Shelov, Cindy L Hoegg, Judith Kelsen, Ana Maria Cardenas, Handy K Lori, Katie L Williams, Talene A Metjian, Molly Hayes
Publikováno v:
Open Forum Infectious Diseases
Background Clinical decision support for Clostridioides difficile infection (CDI) diagnostics reduces inappropriate testing, leading to decreased need for isolation and antibiotic use. Our institution utilized manual discontinuation by laboratory sta
Autor:
Katie L. Williams, Matthew Cannon, Leslie A. Andritsos, Yiming Zhong, James S. Blachly, John C. Byrd, Jennifer A. Woyach, Erich Williams, Taylor D. LaFollette, Xiaoli Zhang, Ching-Shih Chen, Chia Hsien Wu, Dalia El-Gamal, Farrukh T. Awan, Amy Lehman, Jeffrey A. Jones, Kami J. Maddocks, Rosa Lapalombella
Publikováno v:
Blood. 124:1481-1491
Targeting B-cell receptor (BCR) signaling in chronic lymphocytic leukemia (CLL) has been successful with durable remissions observed with several targeted therapeutics. Protein kinase C-β (PKC-β) is immediately downstream of BCR and has been shown
Autor:
David Artis, Krystyna Mozdzanowska, Jeffrey N. Weiser, Qin Liu, Maura C. Strauman, Jan Erikson, Amaya I. Wolf, Hao Shen, Scott E. Hensley, Katie L. Williams, Lisa C. Osborne, David S. Garlick, Andrew J. Caton
Publikováno v:
Virology. :254-265
The response to influenza virus (IAV) infection and severity of disease is highly variable in humans. We hypothesized that one factor contributing to this variability is the presence of specific respiratory tract (RT) microbes. One such microbe is St
Autor:
Pierre Vandepapelière, Marie-Ange Demoitié, Hendrik Streeck, Gilbert Roy, Rachel P. Simmons, Stanley K. Mui, Nesli Basgoz, Mathias Lichterfeld, Marcus Altfeld, Amy Sbrolla, Theresa Flynn, Katie L. Williams, Gerald Voss, Rajesh T. Gandhi, Louise Pedneault, Xu G. Yu, Marguerite Koutsoukos, Lisa McNally, Nicole Burgett-Yandow, Michel Janssens, Patricia Bourguignon
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 59:1-9
Background Induction of HIV-1-specific CD4(+) T-cell responses by therapeutic vaccination represents an attractive intervention to potentially increase immune control of HIV-1. Methods We performed a double-blinded, randomized, placebo-controlled cli
Autor:
Katie L. Williams, Jan Erikson, Michael P. Cancro, Amaya I. Wolf, William J. Quinn, Loren D. Erickson, Eric Meffre, Andrew J. Caton, David Allman, Krystyna Mozdzanowska, Richard J. Bram, Michele H. Metzgar
Publikováno v:
Journal of Clinical Investigation. 121:3954-3964
Antiviral Abs, for example those produced in response to influenza virus infection, are critical for virus neutralization and defense against secondary infection. While the half-life of Abs is short, Ab titers can last a lifetime due to a subset of t
Autor:
Mary Carrington, Sharon Reddy, Bruce D. Walker, Katie L. Williams, Musie Ghebremichael, Douglas Wilson, Marcus Altfeld, Ambrose H. Wong, Galit Alter, Janet Giddy, Thumbi Ndung'u, William H. Carr
Publikováno v:
AIDS Research and Human Retroviruses. 26:459-469
Recent studies suggest that innate immune responses by natural killer (NK) cells play a significant role in restricting human immunodeficiency virus type-1 (HIV-1) pathogenesis. Our aim was to characterize changes in NK cells associated with HIV-1 cl
Publikováno v:
Journal of Virology. 81:12666-12669
Human immunodeficiency virus type 1 (HIV-1) cytotoxic T-lymphocyte escape mutations represent both a major reason for loss of HIV immune control and a considerable challenge for HIV-1 vaccine design. Previous data suggest that initial HIV-1-specific
Autor:
Xu G. Yu, Michael T. Waring, Alicja Trocha, Eric S. Rosenberg, Daniel E. Cohen, Rachel L. Allgaier, Mary N. Johnston, Mathias Lichterfeld, Marcus Altfeld, Todd M. Allen, Tomohiko Koibuchi, Katie L. Williams, Bruce D. Walker, Stanley K. Mui, Mark A. Brockman
Publikováno v:
Journal of Virology. 81:4199-4214
Human immunodeficiency virus type 1 (HIV-1)-specific CD8 + T cells in early infection are associated with the dramatic decline of peak viremia, whereas their antiviral activity in chronic infection is less apparent. The functional properties accounti
Autor:
Photini Kiepiela, Madhu Vajpayee, William H. Hildebrand, Margaret E. Feeney, Richard A. Kaslow, Christian Brander, Yanhua Tang, Nicole Frahm, Eric S. Rosenberg, Montiago X. LaBute, Alisdair Leslie, Paul A. Goepfert, Senica Chetty, Hayley Crawford, Florencia Pereyra, Bruce D. Walker, Mathias Lichterfeld, Marcus Altfeld, Stanley K. Mui, Toshiyuki Miura, Todd M. Allen, Xu G. Yu, Philip J. R. Goulder, Rachel L. Allgaier, Katja Pfafferott, Katie L. Williams
Publikováno v:
Journal of Virology. 81:1619-1631
The relative contributions of HLA alleles and T-cell receptors (TCRs) to the prevention of mutational viral escape are unclear. Here, we examined human immunodeficiency virus type 1 (HIV-1)-specific CD8 + T-cell responses restricted by two closely re