Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Katie L. O'Brien"'
Autor:
Róisín M. Loftus, Nadine Assmann, Nidhi Kedia-Mehta, Katie L. O’Brien, Arianne Garcia, Conor Gillespie, Jens L. Hukelmann, Peter J. Oefner, Angus I. Lamond, Clair M. Gardiner, Katja Dettmer, Doreen A. Cantrell, Linda V. Sinclair, David K. Finlay
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Glutamine can feed into the TCA cycle as a fuel for oxidative phosphorylation and thereby can affect metabolic pathways in lymphocytes. Yet here the authors show that glutamine serves predominantly as a signalling molecule that sustains cMyc expressi
Externí odkaz:
https://doaj.org/article/428103db6a8c40348a0ae092d9d2a982
Autor:
Fionn Ó Marcaigh, David J. Kelly, Darren P. O'Connell, Katie L. O’Brien, Kangkuso Analuddin, Naomi Lawless, Adi Karya, Nicola M. Marples
Publikováno v:
Zoological Journal of the Linnean Society. 186:701-724
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::deb38af8be37abc63f0ef48167003c6e
https://doi.org/10.1093/zoolinnean/zlz022
https://doi.org/10.1093/zoolinnean/zlz022
Autor:
Katie L. O’Brien, David K. Finlay
Publikováno v:
Nature Reviews Immunology. 19:282-290
Natural killer (NK) cells are lymphocytes with important roles in innate and adaptive immune responses to tumours and viral infection. However, in certain chronic diseases, including obesity and cancer, NK cell functional responses are impaired. Rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6643becc7c040a207f30bfcf342ee2ed
https://doi.org/10.1038/s41577-019-0139-2
https://doi.org/10.1038/s41577-019-0139-2
Autor:
Peter J. Oefner, Eimear O'Connor, David K. Finlay, Cathal Keane, Nadine Assmann, Chloe Choi, Katja Dettmer, Jessica F. Walls, Clair M. Gardiner, Katie L. O’Brien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19327b2600dca3d8e6064a85fb3603b7
https://doi.org/10.1002/eji.202048784/v2/response1
https://doi.org/10.1002/eji.202048784/v2/response1
De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells
Autor:
Katie L. O’Brien, Chloe Choi, Peter J. Oefner, Eimear O'Connor, David K. Finlay, Jessica F. Walls, Clair M. Gardiner, Nadine Assmann, Cathal Keane, Katja Dettmer
Publikováno v:
European journal of immunologyReferences. 51(1)
Cellular metabolism is dynamically regulated in NK cells and strongly influences their responses. Metabolic dysfunction is linked to defective NK cell responses in diseases such as obesity and cancer. The transcription factors, sterol regulatory elem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f01dd90e437989c923fe9e4e4634314c
https://pubmed.ncbi.nlm.nih.gov/32946110
https://pubmed.ncbi.nlm.nih.gov/32946110
Autor:
Vanessa Zaiatz-Bittencourt, Nadine Assmann, Lydia Lynch, Clair M. Gardiner, Róisín M. Loftus, Raymond P. Donnelly, Katie L. O’Brien, David K. Finlay, Katja Dettmer, Paul Heinrich, Peter J. Oefner, Lydia Dyck
Publikováno v:
Nature Immunology. 18:1197-1206
Activated natural killer (NK) cells engage in a robust metabolic response that is required for normal effector function. Using genetic, pharmacological and metabolic analyses, we demonstrated an essential role for Srebp transcription factors in cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a1801ed92f84290b2f7aae9c7d83f60
https://doi.org/10.1038/ni.3838
https://doi.org/10.1038/ni.3838
Autor:
Clair M. Gardiner, Nidhi Kedia-Mehta, Arianne Garcia, Doreen A. Cantrell, Nadine Assmann, Katja Dettmer, Peter J. Oefner, Linda V. Sinclair, Katie L. O’Brien, David K. Finlay, Angus I. Lamond, Jens L. Hukelmann, Róisín M. Loftus, Conor Gillespie
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Natural killer (NK) cells are lymphocytes with important anti-tumour functions. Cytokine activation of NK cell glycolysis and oxidative phosphorylation (OXPHOS) are essential for robust NK cell responses. However, the mechanisms leading to this metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31e0554a22d06d9b334c532310b9011
https://doi.org/10.1038/s41467-018-04719-2
https://doi.org/10.1038/s41467-018-04719-2
Autor:
Aoife Durcan, Hannah Cullen, Nora O'Keeffe, Katie L. O’Brien, Ladislav Timulak, James McElvaney
Publikováno v:
Psychotherapy research : journal of the Society for Psychotherapy Research. 29(4)
The classification of generalized anxiety disorder (GAD) is influenced by the tradition of conceptualizing disorders in the context of their clinical presentation and subsequent professional thinking around them. Our qualitative, descriptive-interpre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9a9a187bda7ccd1e88ce96e64131484
https://pubmed.ncbi.nlm.nih.gov/28893153
https://pubmed.ncbi.nlm.nih.gov/28893153