Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Katie L. Hwang"'
Autor:
Jill N. Allen, Surendra Pal Chaudhary, John T. Mullen, Christopher G. Azzoli, Samuel J. Klempner, Eunice L. Kwak, Jeffrey W. Clark, Theodore S. Hong, Ryan B. Corcoran, Lawrence S. Blaszkowsky, Eric Roeland, Aparna Raj Parikh, Jason E. Faris, Andrea L. Russo, Jochen K. Lennerz, Lipika Goyal, Janet E. Murphy, Rebecca S. Heist, Katie L. Hwang, A. John Iafrate, Darrell R. Borger, David P. Ryan
Publikováno v:
Oncologist
BackgroundMetastatic esophagogastric cancers (EGCs) have a poor prognosis with an approximately 5% 5-year survival. Additional treatment approaches are needed. c-MET gene-amplified tumors are an uncommon but potentially targetable subset of EGC. Clin
Publikováno v:
Biomarkers in Medicine. 10:1269-1285
The rapidly growing array of therapeutic options in cancer requires informative biomarkers to guide the rational selection and precision application of appropriate therapies. Circulating biomarkers such as circulating tumor cells have immense potenti
Autor:
Matthew L. Steinhauser, Dean Yimlamai, Wolfram Goessling, Evan C. Lien, Mark R. Sullivan, Allison Tsomides, Joel B. Miesfeld, Brian A. Link, Erin Snay, John M. Asara, Katie L. Hwang, Michael Fort, Sagar Chhangawala, Matthew G. Vander Heiden, Kimberly Y Ma, Fernando D. Camargo, Yariv Houvras, Aaron M. Hosios, Min Yuan, Andrew G. Cox, Kristin K. Brown, Giorgio G. Galli, Brendan H. Fowl
Publikováno v:
bioRxiv
The Hippo pathway and its nuclear effector Yap regulate organ size and cancer formation. While many modulators of Hippo activity have been identified, little is known about the Yap target genes that mediate these growth effects. Here, we show that ya
Autor:
Andrzej Niemierko, Justin F. Gainor, William L. Hwang, Emily Schapira, Katie L. Hwang, Florence K. Keane, Harper Hubbeling
Publikováno v:
JAMA oncology. 4(2)
This cohort study evaluates the clinical outcomes in patients with metastatic lung cancer treated with PD-1/PD-L1 inhibitors and thoracic radiotherapy.
Autor:
John M. Asara, Byung Cheon Lee, Andrew G. Cox, Kimberley J. Evason, Evan C. Lien, Sagar Chhangawala, Jerry R. Heidel, Bryan C. Dickinson, Yariv Houvras, Diane C. Saunders, Christopher J. Chang, Kristin K. Brown, Min Yuan, Allison Tsomides, Wolfram Goessling, Katie L. Hwang, Vadim N. Gladyshev, Andrew J. Kim, Sahar Nissim
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 38
Cox, AG; Tsomides, A; Kim, AJ; Saunders, D; Hwang, KL; Evason, KJ; et al.(2016). Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 113(38), E5562-E5571. doi: 10.1073/pnas.1600204113. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1sx0r2zs
Cox, AG; Tsomides, A; Kim, AJ; Saunders, D; Hwang, KL; Evason, KJ; et al.(2016). Selenoprotein H is an essential regulator of redox homeostasis that cooperates with p53 in development and tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America, 113(38), E5562-E5571. doi: 10.1073/pnas.1600204113. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/1sx0r2zs
© 2016, National Academy of Sciences. All rights reserved. Selenium, an essential micronutrient known for its cancer prevention properties, is incorporated into a class of selenocysteine-containing proteins (selenoproteins). Selenoprotein H (SepH) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615584a446e33e142cd585c9b2072199
https://escholarship.org/uc/item/1sx0r2zs
https://escholarship.org/uc/item/1sx0r2zs
Autor:
Katie L, Hwang, Wolfram, Goessling
Publikováno v:
Advances in experimental medicine and biology. 916
Liver and pancreatic cancers are amongst the leading causes of cancer death. In recent years, genetic and chemical approaches in zebrafish have elucidated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In
Autor:
Wolfram Goessling, Katie L. Hwang
Publikováno v:
Cancer and Zebrafish ISBN: 9783319306520
Liver and pancreatic cancers are amongst the leading causes of cancer death. In recent years, genetic and chemical approaches in zebrafish have elucidated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d66276664ef699876bdac54c4f06af
https://doi.org/10.1007/978-3-319-30654-4_17
https://doi.org/10.1007/978-3-319-30654-4_17
Autor:
Jochen K. Lennerz, A. John Iafrate, Jeffrey W. Clark, John T. Mullen, Aparna Raj Parikh, Jason E. Faris, Ryan B. Corcoran, Andrea L. Russo, Katie L. Hwang, Darrell R. Borger, David P. Ryan, Jackie Szymonifka, Eunice L. Kwak, Theodore S. Hong, Hui Zheng, Janet E. Murphy, Christopher G. Azzoli, Lawrence S. Blaszkowsky, Rebecca S. Heist, Amy Shui
Publikováno v:
Journal of Clinical Oncology. 36:74-74
74 Background: c-MET gene amplified ( MET-amp) tumors have been identified as a rare but targetable subset of esophagogastric cancer (EGC). In a phase I study, patients with MET-amp EGC had a 50% response rate to the oral MET inhibitor AMG 337, with
Autor:
Sagar Chhangawala, Dean Yimlamai, Min Yuan, Sebastian Beltz, John M. Asara, Sahar Nissim, Akihiro Minami, Fernando D. Camargo, Julia Wucherpfennig, Giorgio G. Galli, Yariv Houvras, Wolfram Goessling, Kimberley J. Evason, Andrew G. Cox, David E. Cohen, Evan C. Lien, Didier Y.R. Stainier, Katie L. Hwang, Kristin K. Brown, Keelin O’Connor, Allison Tsomides
Publikováno v:
Nature cell biology
The Hippo pathway is an important regulator of organ size and tumorigenesis. It is unclear, however, how Hippo signalling provides the cellular building blocks required for rapid growth. Here, we demonstrate that transgenic zebrafish expressing an ac
Publikováno v:
Chinese Clinical Oncology. 6:S5-S5
Meningiomas account for approximately one-third of primary central nervous system tumors with a subset that are aggressive and carry significant morbidity and mortality. Treatment of these high-grade meningiomas, classified by the World Health Organi