Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Katie G. Seu"'
Autor:
John G. Noel, Seth W. Ramser, Lori Pitstick, John P. Bonamer, Bryan Mackenzie, Katie G. Seu, Theodosia A. Kalfa, Jose A. Cancelas, Jason C. Gardner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract M-CSF receptor signaling supports the development and survival of mononuclear phagocytes and is thought to play a role in post burn anemia by promoting myeloid lineage bias. We found M-CSF secretion was increased in burn patients and a murin
Externí odkaz:
https://doaj.org/article/574ad174994b4b668e96e765e451a0b2
Autor:
Alina Sadaf, Katie G. Seu, Elizabeth Thaman, Rose Fessler, Diamantis G. Konstantinidis, Holly A. Bonar, Jennifer Korpik, Russell E. Ware, Patrick T. McGann, Charles T. Quinn, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Sickle cell anemia (SCA) is a hereditary hemoglobinopathy with a variable phenotype. There is no single biomarker that adequately predicts disease severity and can be used to monitor treatment response in patients in clinical trials and clinical care
Externí odkaz:
https://doaj.org/article/b9b6c29ecdaf45248ce52b9860c4b661
Autor:
Satheesh Chonat, Mary Risinger, Haripriya Sakthivel, Omar Niss, Jennifer A. Rothman, Loan Hsieh, Stella T. Chou, Janet L. Kwiatkowski, Eugene Khandros, Matthew F. Gorman, Donald T. Wells, Tamara Maghathe, Neha Dagaonkar, Katie G. Seu, Kejian Zhang, Wenying Zhang, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/840996a63d2c4519a193f1ac68e710b4
Autor:
Satheesh Chonat, Mary Risinger, Haripriya Sakthivel, Omar Niss, Jennifer A. Rothman, Loan Hsieh, Stella T. Chou, Janet L. Kwiatkowski, Eugene Khandros, Matthew F. Gorman, Donald T. Wells, Tamara Maghathe, Neha Dagaonkar, Katie G. Seu, Kejian Zhang, Wenying Zhang, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Hereditary spherocytosis (HS) is the most common red blood cell (RBC) membrane disorder causing hereditary hemolytic anemia. Patients with HS have defects in the genes coding for ankyrin (ANK1), band 3 (SLC4A1), protein 4.2 (EPB42), and α (SPTA1) or
Externí odkaz:
https://doaj.org/article/ad840012f1744b04820b5b66c13c0ebd
Publikováno v:
Current Opinion in Hematology. 30:99-105
Autor:
Laurel Romano, Katie G. Seu, Julien Papoin, David E. Muench, Diamantis Konstantinidis, André Olsson, Katrina Schlum, Kashish Chetal, Joel Anne Chasis, Narla Mohandas, Betsy J. Barnes, Yi Zheng, H. Leighton Grimes, Nathan Salomonis, Lionel Blanc, Theodosia A. Kalfa
Publikováno v:
Blood. 140(14)
The erythroblastic island (EBI), composed of a central macrophage surrounded by maturing erythroblasts, is the erythroid precursor niche. Despite numerous studies, its precise composition is still unclear. Using multispectral imaging flow cytometry,
Autor:
Zhaowei Tu, Cuiqing Fan, Ashely K. Davis, Mengwen Hu, Chen Wang, Akhila Dandamudi, Katie G. Seu, Theodosia A. Kalfa, Q. Richard Lu, Yi Zheng
Publikováno v:
Cell reports, vol 40, iss 2
CHD8 is an ATP-dependent chromatin-remodeling factor whose monoallelic mutation defines a subtype of autism spectrum disorders (ASDs). Previous work found that CHD8 is required for the maintenance of hematopoiesis by integrating ATM-P53-mediated surv
Etavopivat, a Pyruvate Kinase Activator in Red Blood Cells, for the Treatment of Sickle Cell Disease
Autor:
Patricia Schroeder, Keertik Fulzele, Sanjeev Forsyth, Maria D. Ribadeneira, Sylvie Guichard, Erik Wilker, C. Gary Marshall, Adam Drake, Rose Fessler, Diamantis G. Konstantinidis, Katie G. Seu, Theodosia A. Kalfa
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 380(3)
Etavopivat is an investigational, oral, small molecule activator of erythrocyte pyruvate kinase (PKR) in development for the treatment of sickle cell disease (SCD) and other hemoglobinopathies. PKR activation is proposed to ameliorate the sickling of
Autor:
Omar Niss, Robert B. Lorsbach, Mikaela Berger, Satheesh Chonat, Morgan McLemore, David Buchbinder, Timothy McCavit, Linda G. Shaffer, Jessica Simpson, Jeffrey H. Schwartz, Jessica Meznarich, Myesa Emberesh, Katie G. Seu, Wenying Zhang, Theodosia A. Kalfa, Ammar Husami, Theodosia Kalfa, Robert Lorsbach, Carolyn Lutzko, Adam Nelson, Charles Quinn, Clarissa Johnson, Jennifer A. Rothman, Sweta Gupta, Mara Nuñez Toscano, Melissa Forouhar, Vinod K. Gidvani-Diaz, James B. Ball, Gavin D. Roach, KayeLyn Wagner, Sam Milanovich, James Boyer, Jane Chawla, Christine Moore Smith, Adrienne Lee, Vlad C. Radulescu, Yasmina L. Abajas, A. Kim Ritchey, Hunter R. Underhill, Yaddanapudi Ravindranath, Niketa C. Shah
Publikováno v:
Blood Cells Mol Dis
Congenital dyserythropoietic anemias (CDAs) are characterized by ineffective erythropoiesis and distinctive erythroblast abnormalities; the diagnosis is often missed or delayed due to significant phenotypic heterogeneity. We established the CDA Regis
Autor:
Alina Sadaf, Katie G. Seu, Elizabeth Thaman, Rose Fessler, Diamantis G. Konstantinidis, Holly A. Bonar, Jennifer Korpik, Russell E. Ware, Patrick T. McGann, Charles T. Quinn, Theodosia A. Kalfa
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 12 (2021)
Frontiers in Physiology, Vol 12 (2021)
Sickle cell anemia (SCA) is a hereditary hemoglobinopathy with a variable phenotype. There is no single biomarker that adequately predicts disease severity and can be used to monitor treatment response in patients in clinical trials and clinical care