Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Katie E. Hebron"'
Autor:
Stacey Stauffer, Jacob S. Roth, Edjay R. Hernandez, Joshua T. Kowalczyk, Nancy E. Sealover, Katie E. Hebron, Amy James, Kristine A. Isanogle, Lisa A. Riffle, Lilia Ileva, Xiaoling Luo, Jin-Qiu Chen, Noemi Kedei, Robert L. Kortum, Haiyan Lei, Jack F. Shern, Joseph D. Kalen, Elijah F. Edmondson, Matthew D. Hall, Simone Difilippantonio, Carol J. Thiele, Marielle E. Yohe
Publikováno v:
Cancers, Vol 16, Iss 13, p 2320 (2024)
Activating mutations in the RAS/MAPK pathway are observed in relapsed neuroblastoma. Preclinical studies indicate that these tumors have an increased sensitivity to inhibitors of the RAS/MAPK pathway, such as MEK inhibitors. MEK inhibitors do not ind
Externí odkaz:
https://doaj.org/article/6aa231f7d2064697bf39a93b7ac6369e
Publikováno v:
Disease Models & Mechanisms, Vol 15, Iss 2 (2022)
The RASopathies are a group of disorders caused by a germline mutation in one of the genes encoding a component of the RAS/MAPK pathway. These disorders, including neurofibromatosis type 1, Noonan syndrome, cardiofaciocutaneous syndrome, Costello syn
Externí odkaz:
https://doaj.org/article/499ee81276df40caa1190455b8675e76
Autor:
Vladimir R. Babaev, Katie E. Hebron, Carrie B. Wiese, Cynthia L. Toth, Lei Ding, Youmin Zhang, James M. May, Sergio Fazio, Kasey C. Vickers, MacRae F. Linton
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 11, Pp 2296-2308 (2014)
Macrophages play crucial roles in the formation of atherosclerotic lesions. Akt, a serine/threonine protein kinase B, is vital for cell proliferation, migration, and survival. Macrophages express three Akt isoforms, Akt1, Akt2, and Akt3, but the role
Externí odkaz:
https://doaj.org/article/4da4d555f5614ee7ad4c847bf68c2fb8
Autor:
Katie E. Hebron, Xiaolin Wan, Jacob S. Roth, David J. Liewehr, Nancy E. Sealover, William J.E. Frye, Angela Kim, Stacey Stauffer, Olivia L. Perkins, Wenyue Sun, Kristine A. Isanogle, Christina M. Robinson, Amy James, Parirokh Awasthi, Priya Shankarappa, Xiaoling Luo, Haiyan Lei, Donna Butcher, Roberta Smith, Elijah F. Edmondson, Jin-Qiu Chen, Noemi Kedei, Cody J. Peer, Jack F. Shern, W. Douglas Figg, Lu Chen, Matthew D. Hall, Simone Difilippantonio, Frederic G. Barr, Robert L. Kortum, Robert W. Robey, Angelina V. Vaseva, Javed Khan, Marielle E. Yohe
Publikováno v:
Clinical Cancer Research. 29:472-487
Purpose: PAX-fusion negative rhabdomyosarcoma (FN RMS) is driven by alterations in the RAS/MAP kinase pathway and is partially responsive to MEK inhibition. Overexpression of IGF1R and its ligands is also observed in FN RMS. Preclinical and clinical
Autor:
Marielle E. Yohe, Javed Khan, Angelina V. Vaseva, Robert W. Robey, Robert L. Kortum, Frederic G. Barr, Simone Difilippantonio, Matthew D. Hall, Lu Chen, W. Douglas Figg, Jack F. Shern, Cody J. Peer, Noemi Kedei, Jin-Qiu Chen, Elijah F. Edmondson, Roberta Smith, Donna Butcher, Haiyan Lei, Xiaoling Luo, Priya Shankarappa, Parirokh Awasthi, Amy James, Christina M. Robinson, Kristine A. Isanogle, Wenyue Sun, Olivia L. Perkins, Stacey Stauffer, Angela Kim, William J.E. Frye, Nancy E. Sealover, David J. Liewehr, Jacob S. Roth, Xiaolin Wan, Katie E. Hebron
Pharmacodynamic response to trametinib/ganitumab in xenograft models does not predict tumor shrinkage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7c566bea37a5d8427b5ace824dcd1e
https://doi.org/10.1158/1078-0432.22488359
https://doi.org/10.1158/1078-0432.22488359
Autor:
Marielle E. Yohe, Javed Khan, Angelina V. Vaseva, Robert W. Robey, Robert L. Kortum, Frederic G. Barr, Simone Difilippantonio, Matthew D. Hall, Lu Chen, W. Douglas Figg, Jack F. Shern, Cody J. Peer, Noemi Kedei, Jin-Qiu Chen, Elijah F. Edmondson, Roberta Smith, Donna Butcher, Haiyan Lei, Xiaoling Luo, Priya Shankarappa, Parirokh Awasthi, Amy James, Christina M. Robinson, Kristine A. Isanogle, Wenyue Sun, Olivia L. Perkins, Stacey Stauffer, Angela Kim, William J.E. Frye, Nancy E. Sealover, David J. Liewehr, Jacob S. Roth, Xiaolin Wan, Katie E. Hebron
Related to Figure 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddd7fae2aafc437f40291da739fe21d2
https://doi.org/10.1158/1078-0432.22488377.v1
https://doi.org/10.1158/1078-0432.22488377.v1
Autor:
Marielle E. Yohe, Javed Khan, Angelina V. Vaseva, Robert W. Robey, Robert L. Kortum, Frederic G. Barr, Simone Difilippantonio, Matthew D. Hall, Lu Chen, W. Douglas Figg, Jack F. Shern, Cody J. Peer, Noemi Kedei, Jin-Qiu Chen, Elijah F. Edmondson, Roberta Smith, Donna Butcher, Haiyan Lei, Xiaoling Luo, Priya Shankarappa, Parirokh Awasthi, Amy James, Christina M. Robinson, Kristine A. Isanogle, Wenyue Sun, Olivia L. Perkins, Stacey Stauffer, Angela Kim, William J.E. Frye, Nancy E. Sealover, David J. Liewehr, Jacob S. Roth, Xiaolin Wan, Katie E. Hebron
Purpose:PAX-fusion negative rhabdomyosarcoma (FN RMS) is driven by alterations in the RAS/MAP kinase pathway and is partially responsive to MEK inhibition. Overexpression of IGF1R and its ligands is also observed in FN RMS. Preclinical and clinical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f2495e02f2004856ed709224efafc9
https://doi.org/10.1158/1078-0432.c.6532697.v1
https://doi.org/10.1158/1078-0432.c.6532697.v1
Autor:
Andries Zijlstra, John D. Lewis, Tatiana Ketova, Giovanna A. Giannico, Joseph L. Chin, Andrew K. Williams, Jose A. Gomez-Lemus, Venu Chalasani, Susanne M. Chan, Shanna A. Arnold, Celestial Jones-Paris, Katie E. Hebron, Catalina Vasquez, Carlos H. Martínez, Trenis D. Palmer
PDF - 5142K, CD151 clustering at areas of cell-cell contact in vivo (S1); Cell-cell adhesion in response to CD151 clustering (S2); MAB 1A5 binds to CD151 not engaged with α3 integrin in HEp3 cells (S3); MAb 1A5 recognizes the integrin-binding domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13840af29fb1e40e1be29bb44869bcfa
https://doi.org/10.1158/0008-5472.22399085.v1
https://doi.org/10.1158/0008-5472.22399085.v1
Autor:
Andries Zijlstra, John D. Lewis, Tatiana Ketova, Giovanna A. Giannico, Joseph L. Chin, Andrew K. Williams, Jose A. Gomez-Lemus, Venu Chalasani, Susanne M. Chan, Shanna A. Arnold, Celestial Jones-Paris, Katie E. Hebron, Catalina Vasquez, Carlos H. Martínez, Trenis D. Palmer
MOV - 8452K, CD151 clustering at areas of cell-cell contact in HEp3 tumor cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f90c896f55f39a46609cec2877ee5fb
https://doi.org/10.1158/0008-5472.22399082.v1
https://doi.org/10.1158/0008-5472.22399082.v1
Autor:
Andries Zijlstra, John D. Lewis, Tatiana Ketova, Giovanna A. Giannico, Joseph L. Chin, Andrew K. Williams, Jose A. Gomez-Lemus, Venu Chalasani, Susanne M. Chan, Shanna A. Arnold, Celestial Jones-Paris, Katie E. Hebron, Catalina Vasquez, Carlos H. Martínez, Trenis D. Palmer
PDf - 92K, Legends for Supplementary Figures S1-S8 as well as Supplementary Movie S1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4903dbc8a370f22c9792d48bab4208bd
https://doi.org/10.1158/0008-5472.22399088
https://doi.org/10.1158/0008-5472.22399088