Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Katie E Glen"'
Autor:
Sheila Ranganath, Ashok Bhandari, Nicole Avitahl-Curtis, Jaimee McMahon, Derek Wachtel, Jenny Zhang, Christopher Leitheiser, Sylvie G Bernier, Guang Liu, Tran T Tran, Herodion Celino, Jenny Tobin, Joon Jung, Hong Zhao, Katie E Glen, Chris Graul, Aliesha Griffin, Wayne C Schairer, Carolyn Higgins, Tammi L Reza, Eva Mowe, Sam Rivers, Sonya Scott, Alex Monreal, Courtney Shea, Greg Bourne, Casey Coons, Adaline Smith, Kim Tang, Ramya A Mandyam, Jaime Masferrer, David Liu, Dinesh V Patel, Angelika Fretzen, Craig A Murphy, G Todd Milne, Mark L Smythe, Kenneth E Carlson
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141330 (2015)
Interleukin-6 (IL-6) is an important member of the cytokine superfamily, exerting pleiotropic actions on many physiological processes. Over-production of IL-6 is a hallmark of immune-mediated inflammatory diseases such as Castleman's Disease (CD) and
Externí odkaz:
https://doaj.org/article/79b1eaa807e1438c8eaa8708c553dbc5
Publikováno v:
Biotechnology progressREFERENCES. 37(6)
Manufacturing of cell therapy products requires sufficient understanding of the cell culture variables and associated mechanisms for adequate control and risk analysis. The aim of this study was to apply an unstructured ordinary differential equation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665a2872834ba9da0925857da7e32b75
https://pubmed.ncbi.nlm.nih.gov/34455707
https://pubmed.ncbi.nlm.nih.gov/34455707
Autor:
Sourav Ghosh, Carlos da Silva Granja, Katie E. Glen, Niklas Sandström, Robert Thomas, Victor P. Ostanin
Publikováno v:
Biosensors and Bioelectronics: X, Vol 6, Iss, Pp 100057-(2020)
Cell therapy manufacturing is limited by lack of online tools capable of realtime in-process monitoring, particularly of simultaneous changes in multiple orthogonal (mutually independent) parameters. Here, we studied changes in CD36 expression, numbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2eeb62e94458477f539d022df793beb
http://www.sciencedirect.com/science/article/pii/S2590137020300236
http://www.sciencedirect.com/science/article/pii/S2590137020300236
Publikováno v:
Cytotherapy. 23:S198-S199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51e6fc0179aee9c09a2cdfb86090e40a
https://doi.org/10.1016/s1465324921006228
https://doi.org/10.1016/s1465324921006228
Autor:
Rebecca L. L. Moore, Matthew J. Worrallo, Peter D. Mitchell, Jon Harriman, Katie E. Glen, Robert J. Thomas
Publikováno v:
BMC Biotechnology, Vol 17, Iss 1, Pp 1-11 (2017)
Background Umbilical cord blood provides a source of hematopoietic stem cells for transplantation with immunological and availability advantages over conventional bone marrow sources. Limited cell numbers and slower engraftment from umbilical cord bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::158f3a240e904edf8b53012185adc9ac
http://link.springer.com/article/10.1186/s12896-017-0383-0
http://link.springer.com/article/10.1186/s12896-017-0383-0
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 12:e368-e378
Manufacture of red blood cells (RBCs) from progenitors has been proposed as a method to reduce reliance on donors. Such a process would need to be extremely efficient for economic viability given a relatively low value product and high 2E12 cell dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cdc9bf794920dc8c0cad6edd97e9df2
https://doi.org/10.1002/term.2337
https://doi.org/10.1002/term.2337
Publikováno v:
Cytotherapy. 22:S147-S148
Background & Aim One of the most effective vehicles for delivery of therapeutic nucleic acids are viral vectors, demonstrated by their utility in many commercial cell and gene therapies. Despite success, gaps remain in the optimization of viral vecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f026953b31d83c8682c185a3b068a6
https://doi.org/10.1016/j.jcyt.2020.03.300
https://doi.org/10.1016/j.jcyt.2020.03.300
Publikováno v:
Cytotherapy. 22:S160
Background & Aim Advanced Therapy Medicinal Products (ATMPs) pose a continuing challenge to manufacturing process development. Despite the adoption of a structured approach to development through systematic frameworks such as Quality by Design, a cos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56e33792d0aa6616050f5f341fd0fed
https://doi.org/10.1016/j.jcyt.2020.03.333
https://doi.org/10.1016/j.jcyt.2020.03.333
Publikováno v:
Cytotherapy. 22:S159
Background & Aim Manufacturing requires sufficient understanding of the variables and associated mechanisms for adequate control and risk analysis. In the case of cell therapies, relatively complex relationships between inputs/parameter controls and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d856c8a7c6b9ad425f2f5851a5f0eab
https://doi.org/10.1016/j.jcyt.2020.03.330
https://doi.org/10.1016/j.jcyt.2020.03.330