Survival of aging CD264 + and CD264 − populations of human bone marrow mesenchymal stem cells is independent of colony‐forming efficiency

Autor: H. Alan Tucker, Carson T. Discher, Sean D. Madsen, Katie C. Russell, Mimi C. Sammarco, Margaret K. Giler, Sean H. Jones, Dyllan C. Muller, Bruce A. Bunnell, Kim C. O'Connor, Georgina L Dobek

Publikováno v: Biotechnology and Bioengineering. 117:223-237

In vivo mesenchymal stem cell (MSC) survival is relevant to therapeutic applications requiring engraftment and potentially to nonengraftment applications as well. MSCs are a mixture of progenitors at different stages of cellular aging, but the contri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::479217026795f2b4d662d471e81cb43d
https://doi.org/10.1002/bit.27195

Back Cover Image, Volume 117, Number 1, January 2020

Autor: Sean D. Madsen, Sean H. Jones, H. Alan Tucker, Margaret K. Giler, Dyllan C. Muller, Carson T. Discher, Katie C. Russell, Georgina L. Dobek, Mimi C. Sammarco, Bruce A. Bunnell, Kim C. O'Connor

Publikováno v: Biotechnology and Bioengineering. 117

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1402fe38ad4caf92843b9763e0418f48
https://doi.org/10.1002/bit.27184

Cell-Surface Expression of Neuron-Glial Antigen 2 (NG2) and Melanoma Cell Adhesion Molecule (CD146) in Heterogeneous Cultures of Marrow-Derived Mesenchymal Stem Cells

Autor: H. Alan Tucker, Andrew S. Gaynor, Wendy D. Schober, Kim C. O'Connor, Shuwen Lin, Katie C. Russell, Bruce A. Bunnell, Karen L. Strickler, Michelle Lacey, Michael Andreeff

Publikováno v: Tissue Engineering Part A. 19:2253-2266

Cellular heterogeneity of mesenchymal stem cells (MSCs) impedes their use in regenerative medicine. The objective of this research is to identify potential biomarkers for the enrichment of progenitors from heterogeneous MSC cultures. To this end, the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4af0d8ed74f9b0715dd60e9c6e10efd
https://doi.org/10.1089/ten.tea.2012.0649

Regulating in Vitro Motility of Human Mesenchymal Stem Cells with Macrophage Migration Inhibitory Factor (MIF) and a Small-Molecule MIF Antagonist

Autor: Darwin J. Prockop, Donald G. Phinney, Kim C. O'Connor, Katie C. Russell, Benjamin W. Fischer-Valuck, Bonnie L. Barrilleaux

Publikováno v: Proceedings of the 21st Annual Meeting of the European Society for Animal Cell Technology (ESACT), Dublin, Ireland, June 7-10, 2009 ISBN: 9789400708839

Human mesenchymal stem cells (MSCs) from bone marrow possess a remarkable capacity to home to and regenerate damaged tissue, but the molecular mechanisms governing their migration and homing are not well defined. The present study reveals that a pote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae07ca2081f69b60f0391c728b80fd07
https://doi.org/10.1007/978-94-007-0884-6_26

In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment

Autor: Katie C. Russell, Kim C. O'Connor, Kristin E. Meyertholen, Michelle Lacey, Donald G. Phinney, Bonnie L. Barrilleaux

Publikováno v: Stem cells (Dayton, Ohio). 28(4)

In regenerative medicine, bone marrow is a promising source of mesenchymal stem cells (MSCs) for a broad range of cellular therapies. This research addresses a basic prerequisite to realize the therapeutic potential of MSCs by developing a novel high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d6c343a996379b03017b16e67c0de6
https://pubmed.ncbi.nlm.nih.gov/20127798