Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Katie A Thies"'
Autor:
Jinghai Wu, Xin Liu, Sunayana G Nayak, Jason R Pitarresi, Maria C Cuitiño, Lianbo Yu, Blake E Hildreth, Katie A Thies, Daniel J Schilling, Soledad A Fernandez, Gustavo Leone, Michael C Ostrowski
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184984 (2017)
The contribution of the tumor microenvironment to the development of pancreatic adenocarcinoma (PDAC) is unclear. The LSL-KrasG12D/+;LSL-p53R172H/+;Pdx-1-Cre (KPC) tumor model, which is widely utilized to faithfully recapitulate human pancreatic canc
Externí odkaz:
https://doaj.org/article/5070e05f06694d96863c592eb17d18ef
Autor:
Katie A. Thies, Matthew W. Cole, Rachel E. Schafer, Jonathan M. Spehar, Dillon S. Richardson, Sarah A. Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Reena Shakya, Sue E. Knoblaugh, Cynthia D. Timmers, Michael C. Ostrowski, Arnab Chakravarti, Gina M. Sizemore, Steven T. Sizemore
Publikováno v:
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Abstract Background Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part to the lack of targe
Externí odkaz:
https://doaj.org/article/986a2f2be5dc406fa9d8fb78e612f5b5
Autor:
Jonathan M. Spehar, Katie A. Thies, Matthew W. Cole, Rachel E. Schafer, Dillon S. Richardson, Sarah A. Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Sue E. Knoblaugh, Cynthia D. Trimmers, Gina M. Sizemore, Steven T. Sizemore
Publikováno v:
Cancer Research. 82:PD3-05
Background: Breast Cancer (BC) is the most common cancer and leading cause of cancer associated mortality in women worldwide. TNBC patients have the highest mortality mainly due to lack of receptors for targeted therapies. RalA and RalB are small GTP
Autor:
Luke Russell, Sarah A. Steck, Bhuvaneswari Ramaswamy, Daniel G. Stover, Jose Otero, Zaibo Li, Robert Pilarski, Jonathan M. Spehar, Jonathan P. Godbout, Raleigh D. Kladney, Michael C. Ostrowski, Gustavo Leone, Gina M. Sizemore, Steven T. Sizemore, Arnab Chakravarti, Maria C. Cuitiño, Blake E. Hildreth, Christopher Koivisto, Anisha M. Hammer, Lynn Schoenfield, Manjusri Das, Katie A. Thies, Anthony J. Trimboli, Jennifer A. Geisler, Chelsea Bolyard, Matthew D. Ringel, Balveen Kaur, Jerome F. Bey
Publikováno v:
Cancer Research. 81:606-618
Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred lig
Autor:
Alo Ray, Matthew W. Cole, Gina M. Sizemore, Sarah A. Steck, Sue E. Knoblaugh, Arnab Chakravarti, Cynthia Timmers, Steven T. Sizemore, Manjusri Das, Katie A. Thies, Arthur W. Lian, Rachel E. Schafer, Jonathan M. Spehar, Dillon S. Richardson, Reena Shakya, Michael C. Ostrowski
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-17 (2021)
Background Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part to the lack of targeted treat
Autor:
Dillion Richardson, Reena Shakya, Michael Ostrowski, Matthew W. Cole, Rachel E. Schafer, Cynthia Timmers, Alo Ray, Arnab Chakravarti, Steven T. Sizemore, Sue E. Knoblaugh, Manjusri Das, Jonathan M. Spehar, Arthur W. Lian, Gina M. Sizemore, Katie A. Thies, Sarah Streck
Publikováno v:
The FASEB Journal. 35
Autor:
Julia F. Charles, S. Sharma, Heather A. Carey, Thomas J. Rosol, Devadoss J. Samuvel, Michael C. Ostrowski, Blake E. Hildreth, Katie A. Thies, Ramiro E. Toribio
Publikováno v:
iScience, Vol 11, Iss, Pp 238-245 (2019)
iScience
iScience
Summary Bone-resorbing osteoclasts (OCs) are derived from myeloid precursors (MPs). Several transcription factors are implicated in OC differentiation and function; however, their hierarchical architecture and interplay are not well known. Analysis f
Autor:
Julia E Lefler, Catherine B MarElia-Bennett, Katie A Thies, Blake E Hildreth, Sudarshana M Sharma, Jason R Pitarresi, Lu Han, Caroline Everett, Christopher Koivisto, Maria C Cuitino, Cynthia D Timmers, Elizabeth O’Quinn, Melodie Parrish, Martin J Romeo, Amanda J Linke, G Aaron Hobbs, Gustavo Leone, Denis C Guttridge, Teresa A Zimmers, Gregory B Lesinski, Michael C Ostrowski
Publikováno v:
Life Science Alliance. 5:e202201460
Pancreatic ductal adenocarcinoma (PDAC) is associated with an incredibly dense stroma, which contributes to its recalcitrance to therapy. Cancer-associated fibroblasts (CAFs) are one of the most abundant cell types within the PDAC stroma and have con
Autor:
Katie A Thies, Matthew W. Cole, Rachel E Schafer, Jonathan M Spehar, Dillon S. Richardson, Sarah A Steck, Manjusri Das, Arthur W. Lian, Alo Ray, Reena Shakya, Sue E Knoblaugh, Cynthia D Timmers, Michael C Ostrowski, Arnab Chakravarti, Gina M Sizemore, Steven T Sizemore
Background: Breast cancer (BC) is the most common cancer in women and the leading cause of cancer-associated mortality in women. In particular, triple-negative BC (TNBC) has the highest rate of mortality due in large part to the lack of targeted trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d93a3e9e50a1b7824332bf0090be1158
https://doi.org/10.21203/rs.3.rs-327911/v1
https://doi.org/10.21203/rs.3.rs-327911/v1
Publikováno v:
Journal of Visualized Experiments.
Metastasis, the primary cause of morbidity and mortality for most cancer patients, can be challenging to model preclinically in mice. Few spontaneous metastasis models are available. Thus, the experimental metastasis model involving tail-vein injecti