Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Katie, Seo"'
Autor:
Olga K. Weinberg, Athena M. Cherry, Li Ren, Robert S. Ohgami, Mahesh Seetharam, Daniel A. Arber, Jason Gotlib, Lisa Ma, Katie Seo
Publikováno v:
American Journal of Clinical Pathology. 142:190-195
Objectives: Acute myeloid leukemia (AML) with monosomal karyotype (MK) recently has been reported to be associated with worse outcome than the traditional complex karyotype. Methods: In this retrospective study of 111 patients with AML, we identified
Autor:
Scott D. Boyd, Randy A. Albrecht, Katherine J. L. Jackson, Ramona A. Hoh, Jaume Pons, Arvind Rajpal, Jonathan Laserson, Mark M. Davis, Katie Seo, Adolfo García-Sastre, Daphne Koller, Cornelia L. Dekker, Thaddeus C. Gurley, Yi Liu, Hua-Xin Liao, Birgitte B. Simen, M. Anthony Moody, Jacob Glanville, Andrew Fire, Javier Chaparro-Riggers, Emmanuel B. Walter, Krishna M. Roskin, Barton F. Haynes, Bozena Hanczaruk, Eleanor L. Marshall
Publikováno v:
Cell Host & Microbe. 16:105-114
SummaryB cells produce a diverse antibody repertoire by undergoing gene rearrangements. Pathogen exposure induces the clonal expansion of B cells expressing antibodies that can bind the infectious agent. To assess human B cell responses to trivalent
Autor:
Daphne Koller, Scott D. Boyd, Jonathan Laserson, Cornelia L. Dekker, Eleanor L. Marshall, Katherine J. L. Jackson, Mark M. Davis, Andrew Fire, Krishna M. Roskin, Chen Wang, David Furman, Tho D. Pham, Yi Liu, Katie Seo, Lan T. Xu, Ji-Yeun Lee
Publikováno v:
The Journal of Immunology. 192:603-611
Elderly humans show decreased humoral immunity to pathogens and vaccines, yet the effects of aging on B cells are not fully known. Chronic viral infection by cytomegalovirus (CMV) is implicated as a driver of clonal T cell proliferations in some agin
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Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 21:79-84
BACKGROUND CXC chemokine receptor (CXCR4) has been shown to be expressed in a subset of acute myeloid leukemia (AML) patients and is correlated with a poor prognosis. CXCR4 expression appears to be an independent prognostic factor for survival in a h
Autor:
Akanksha Verma, Ryan M. Loughran, Alec C. Kimmelman, Zhiwei Yang, Nullin Divecha, David Weinkove, Elite Possik, Lewis C. Cantley, Olivier Elemento, Yilun Ma, Mark R. Lundquist, Jared L. Johnson, Tarika Vijayaraghavan, Jenny C.Y. Wong, Mark A. Rubin, Annan Yang, Katie Seo-Kyoung Hwang, Archna Ravi, Chantal Pauli, Brooke M. Emerling, Marcus D. Goncalves, Arnim Pause, John M. Asara
Publikováno v:
Molecular Cell. 70:531-544.e9
While the majority of phosphatidylinositol-4, 5-bisphosphate (PI-4, 5-P(2)) in mammalian cells is generated by the conversion of phosphatidylinositol-4-phosphate (PI-4-P) to PI-4, 5-P(2), a small fraction can be made by phosphorylating phosphatidylin
Publikováno v:
Leukemia & Lymphoma. 51:1356-1359
Classical Hodgkin lymphomas (CHLs) with a T-cell clone are uncommon, and have unknown biologic potential. We describe a CHL presenting with a clonal T-cell receptor (TCR) gene rearrangement with an...
Autor:
Janis M. Taube, James L. Zehnder, Uma Sundram, Natalie Viakhereva, Youn H. Kim, Iris Schrijver, Bing Zhang, Andrew H. Beck, Katie Seo, Jeffrey Zwerner, Daniel A. Arber, Sabine Kohler
Publikováno v:
The Journal of Molecular Diagnostics. 12:320-327
The distinction between mycosis fungoides (MF) and inflammatory dermatoses (ID) by clinicopathologic criteria can be challenging. There is limited information regarding the performance characteristics and utility of TCRG and TCRB clonality assays in
Publikováno v:
The Journal of Molecular Diagnostics. 11:319-323
The goal of the study was to compare the performance of a fluorescence-based multiplex PCR fragment analysis to a direct sequencing method for detecting CEBPA mutations in patients with acute myeloid leukemia. Thirty-three samples were selected from
Autor:
Joon H. Park, Mark M. Davis, David Furman, Ji-Yeun Lee, Judith A. James, Noa Simchoni, Katie Seo, Krishna M. Roskin, Scott D. Boyd, Cornelia L. Dekker, Ramona A. Hoh, Tho D. Pham, Charlotte Cunningham-Rundles, Yi Liu, Kari C. Nadeau
Publikováno v:
Science Translational Medicine. 7
Common variable immune deficiency (CVID) is the most common symptomatic primary immune deficiency, affecting ~1 in 25,000 persons. These patients suffer from impaired antibody responses, autoimmunity, and susceptibility to lymphoid cancers. To explor