Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Katie, Bentley"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract Endothelial cells are key players in the cardiovascular system. Among other things, they are responsible for sprouting angiogenesis, the process of new blood vessel formation essential for both health and disease. Endothelial cells are stron
Externí odkaz:
https://doaj.org/article/cb191cbcb77248da8113260fe334563f
Autor:
Laura A. Tiemeijer, Tommaso Ristori, Oscar M.J. A. Stassen, Jaakko J. Ahlberg, Jonne J.J. de Bijl, Christopher S. Chen, Katie Bentley, Carlijn V.C. Bouten, Cecilia M. Sahlgren
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104306- (2022)
Summary: Spatial regulation of angiogenesis is important for the generation of functional engineered vasculature in regenerative medicine. The Notch ligands Jag1 and Dll4 show distinct expression patterns in endothelial cells and, respectively, promo
Externí odkaz:
https://doaj.org/article/12b2080bc44b4032aee0d44300b97ab0
Autor:
Zain Alhashem, Dylan Feldner-Busztin, Christopher Revell, Macarena Alvarez-Garcillan Portillo, Karen Camargo-Sosa, Joanna Richardson, Manuel Rocha, Anton Gauert, Tatianna Corbeaux, Martina Milanetto, Francesco Argenton, Natascia Tiso, Robert N Kelsh, Victoria E Prince, Katie Bentley, Claudia Linker
Publikováno v:
eLife, Vol 11 (2022)
Coordination of cell proliferation and migration is fundamental for life, and its dysregulation has catastrophic consequences, such as cancer. How cell cycle progression affects migration, and vice versa, remains largely unknown. We address these que
Externí odkaz:
https://doaj.org/article/46c887effd434e8e951b0000a22ed165
Autor:
Bentley, John
Publikováno v:
Lilacs: Quarterly Journal of the International Lilac Society; Summer2010, Vol. 39 Issue 3, p88-91, 4p
Autor:
Robert Hinch, William J M Probert, Anel Nurtay, Michelle Kendall, Chris Wymant, Matthew Hall, Katrina Lythgoe, Ana Bulas Cruz, Lele Zhao, Andrea Stewart, Luca Ferretti, Daniel Montero, James Warren, Nicole Mather, Matthew Abueg, Neo Wu, Olivier Legat, Katie Bentley, Thomas Mead, Kelvin Van-Vuuren, Dylan Feldner-Busztin, Tommaso Ristori, Anthony Finkelstein, David G Bonsall, Lucie Abeler-Dörner, Christophe Fraser
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 7, p e1009146 (2021)
SARS-CoV-2 has spread across the world, causing high mortality and unprecedented restrictions on social and economic activity. Policymakers are assessing how best to navigate through the ongoing epidemic, with computational models being used to predi
Externí odkaz:
https://doaj.org/article/40c60c6d49f340eba2196f65ed314e7d
Autor:
Claudia Prahst, Parham Ashrafzadeh, Thomas Mead, Ana Figueiredo, Karen Chang, Douglas Richardson, Lakshmi Venkaraman, Mark Richards, Ana Martins Russo, Kyle Harrington, Marie Ouarné, Andreia Pena, Dong Feng Chen, Lena Claesson-Welsh, Kin-Sang Cho, Claudio A Franco, Katie Bentley
Publikováno v:
eLife, Vol 9 (2020)
As the general population ages, more people are affected by eye diseases, such as retinopathies. It is therefore critical to improve imaging of eye disease mouse models. Here, we demonstrate that 1) rapid, quantitative 3D and 4D (time lapse) imaging
Externí odkaz:
https://doaj.org/article/d277767636ea4911b66efae5c50328a8
Autor:
Donna J. Page, Raphael Thuret, Lakshmi Venkatraman, Tokiharu Takahashi, Katie Bentley, Shane P. Herbert
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3139-3151.e5 (2019)
Summary: Angiogenesis is driven by the coordinated collective branching of specialized leading “tip” and trailing “stalk” endothelial cells (ECs). While Notch-regulated negative feedback suppresses excessive tip selection, roles for positive
Externí odkaz:
https://doaj.org/article/d2eb7ce923394870b15b027b2afb2391
Autor:
Bert Cruys, Brian W. Wong, Anna Kuchnio, Dries Verdegem, Anna Rita Cantelmo, Lena-Christin Conradi, Saar Vandekeere, Ann Bouché, Ivo Cornelissen, Stefan Vinckier, Roeland M. H. Merks, Elisabetta Dejana, Holger Gerhardt, Mieke Dewerchin, Katie Bentley, Peter Carmeliet
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Glycolytic regulator PFKFB3 is a key player in vessel sprouting. Here the authors develop a computational model predicting that PFKFB3 drives endothelial cell rearrangement during vessel sprouting by promoting filopodia formation and reducing interce
Externí odkaz:
https://doaj.org/article/f168b79c697d4569b921c383b7c0a3c0
Autor:
Xiujuan Li, Narendra Padhan, Elisabet O. Sjöström, Francis P. Roche, Chiara Testini, Naoki Honkura, Miguel Sáinz-Jaspeado, Emma Gordon, Katie Bentley, Andrew Philippides, Vladimir Tolmachev, Elisabetta Dejana, Radu V. Stan, Dietmar Vestweber, Kurt Ballmer-Hofer, Christer Betsholtz, Kristian Pietras, Leif Jansson, Lena Claesson-Welsh
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Signals through VEGF receptor 2 (VEGFR2) increase vascular permeability, promoting cancer progression. Here the authors show that a point mutation in VEGFR2 preventing its auto-phosphorylation leads to reduced metastatic spread and improved response
Externí odkaz:
https://doaj.org/article/b507e4a16cf547ee96f8120a0c5f0330
Autor:
Nikolaos Kakogiannos, Anna Agata Scalise, Emanuele Martini, Claudio Maderna, Serena Magni, Giorgia Serena Gullotta, Maria Grazia Lampugnani, Fabio Iannelli, Galina V. Beznoussenko, Alexander A. Mironov, Camilla Cerutti, Katie Bentley, Andrew Philippides, Federica Zanardi, Marco Bacigaluppi, Gianvito Martino, Elisabetta Dejana, Monica Giannotta
The blood–brain barrier (BBB) acquires unique properties for regulation of the neuronal function during development. The genesis of the BBB coupled with angiogenesis is orchestrated by the Wnt/β-catenin signaling pathway. Aside from the importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa871fa5ebf3fcb71e840795e426a84d
https://doi.org/10.1101/2022.09.09.507316
https://doi.org/10.1101/2022.09.09.507316
