Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Katia Stefanantoni"'
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 1, Pp 120-132 (2024)
Systemic sclerosis (SSc) is a rare autoimmune disease whose molecular mechanisms are not yet fully understood. There is no definitive cure, and the main causes of death are pulmonary fibrosis and pulmonary arterial hypertension. Here, we focus on the
Externí odkaz:
https://doaj.org/article/2cdb862ad90d4c3e8a2bc0d1567dc684
Autor:
Anna Mennella, Katia Stefanantoni, Raffaella Palazzo, Giuseppe Ocone, Immacolata Pietraforte, Simona Truglia, Ilaria Bisconti, Alba Pisacreta, Valeria Riccieri, Roberto Lande, Loredana Frasca
Publikováno v:
Reports, Vol 7, Iss 3, p 66 (2024)
Background: Systemic sclerosis (SSc) is an autoimmune disease characterized by vascular and immunity alterations and skin/internal organ fibrosis. Aberrant levels of plasma CXCL4, CXCL4–RNA/DNA complexes, type I IFN (IFN-I) and anti-CXCL4 antibodie
Externí odkaz:
https://doaj.org/article/f140cd011037435a8c6091acb4374b8c
Autor:
Raffaella Palazzo, Katia Stefanantoni, Marius Cadar, Alessia Butera, Valeria Riccieri, Roberto Lande, Loredana Frasca
Publikováno v:
Antibodies, Vol 11, Iss 4, p 77 (2022)
Systemic sclerosis (SSc) is a chronic disease characterized by skin/internal organ fibrosis, vasculopathy and autoimmunity. Chemokine (C-X-C motif) ligand 4 (CXCL4) is an early SSc biomarker that predicts worse disease outcome. We previously reported
Externí odkaz:
https://doaj.org/article/4a043ee123a249aeaa653ce32d41d084
Autor:
Immacolata Pietraforte, Alessia Butera, Lucia Gaddini, Anna Mennella, Raffaella Palazzo, Doriana Campanile, Katia Stefanantoni, Valeria Riccieri, Roberto Lande, Loredana Frasca
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 653 (2022)
CXCL4 is an important biomarker of systemic sclerosis (SSc), an incurable autoimmune disease characterized by vasculopathy and skin/internal organs fibrosis. CXCL4 contributes to the type I interferon (IFN-I) signature, typical of at least half of SS
Externí odkaz:
https://doaj.org/article/c83e85e247dd4485b62b5125f7e29f22
Autor:
Tania Colasanti, Katia Stefanantoni, Cristina Fantini, Clarissa Corinaldesi, Massimiliano Vasile, Francesco Marampon, Luigi Di Luigi, Cristina Antinozzi, Paolo Sgrò, Andrea Lenzi, Valeria Riccieri, Clara Crescioli
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 10150 (2022)
The prostacyclin analogue iloprost is used to treat vascular alterations and digital ulcers, the early derangements manifesting in systemic sclerosis (SSc), an autoimmune disease leading to skin and organ fibrosis. Bioindicator(s) of SSc onset and pr
Externí odkaz:
https://doaj.org/article/760e64c1d1b34fc699ce9a4eada80c53
Autor:
Roberto Lande, Ernest Y. Lee, Raffaella Palazzo, Barbara Marinari, Immacolata Pietraforte, Giancarlo Santiago Santos, Yves Mattenberger, Francesca Spadaro, Katia Stefanantoni, Nicoletta Iannace, Aleksandra Maria Dufour, Mario Falchi, Manuela Bianco, Elisabetta Botti, Luca Bianchi, Montserrat Alvarez, Valeria Riccieri, Marie-Elise Truchetet, Gerard C.L. Wong, Carlo Chizzolini, Loredana Frasca
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CXCL4 is an inflammatory chemokine signaling through CXCR3 receptor. Here the authors show a CXCR3-independent function of CXCL4: it forms liquid crystals with DNA, potentiating mammalian and bacterial DNA recognition by TLR9, thereby amplifying inte
Externí odkaz:
https://doaj.org/article/a467d41eb1b041d3bfc13521f62a91e8
Autor:
Roberto Lande, Raffaella Palazzo, Anna Mennella, Immacolata Pietraforte, Marius Cadar, Katia Stefanantoni, Curdin Conrad, Valeria Riccieri, Loredana Frasca
Publikováno v:
Antibodies, Vol 10, Iss 2, p 12 (2021)
Chemokine (C-X-C motif) ligand 4 (CXCL4) is a biomarker of unfavorable prognosis in Systemic Sclerosis (SSc), a potentially severe autoimmune condition, characterized by vasculitis, fibrosis and interferon (IFN)-I-signature. We recently reported that
Externí odkaz:
https://doaj.org/article/6c47414193ba4bc98138d87625e5fa3d
Autor:
Roberto Lande, Immacolata Pietraforte, Anna Mennella, Raffaella Palazzo, Francesca Romana Spinelli, Konstantinos Giannakakis, Francesca Spadaro, Mario Falchi, Valeria Riccieri, Katia Stefanantoni, Curdin Conrad, Cristiano Alessandri, Fabrizio Conti, Loredana Frasca
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 1650 (2021)
LL37 acts as T-cell/B-cell autoantigen in Systemic lupus erythematosus (SLE) and psoriatic disease. Moreover, when bound to “self” nucleic acids, LL37 acts as “danger signal,” leading to type I interferon (IFN-I)/pro-inflammatory factors prod
Externí odkaz:
https://doaj.org/article/9a420d58abbb432c92e69ffeae8f672a
Autor:
Roberto Lande, Anna Mennella, Raffaella Palazzo, Immacolata Pietraforte, Katia Stefanantoni, Nicoletta Iannace, Alessia Butera, Monica Boirivant, Roberta Pica, Curdin Conrad, Carlo Chizzolini, Valeria Riccieri, Loredana Frasca
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5102 (2020)
Systemic sclerosis (SSc) is characterized by skin/internal organ fibrosis, vasculopathy and autoimmunity. Chemokine (C-X-C motif) ligand 4 (CXCL4) is an SSc biomarker, predicting unfavorable prognosis and lung fibrosis. CXCL4 binds DNA/RNA and favors
Externí odkaz:
https://doaj.org/article/6477cd402c064c8881e4c46bccbbfb30
Autor:
Davide Mohammad Reza Beigi, Greta Pellegrino, Marius Cadar, Ilaria Bisconti, Francesca Romana Di Ciommo, Katia Stefanantoni, Fabrizio Conti, Valeria Riccieri
Publikováno v:
Open Access Rheumatology: Research and Reviews. 14:133-139
Davide Mohammad Reza Beigi, Greta Pellegrino, Marius Cadar, Ilaria Bisconti, Francesca Romana Di Ciommo, Katia Stefanantoni, Fabrizio Conti, Valeria Riccieri Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari, Sapienza