Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Katia K Mattis"'
Autor:
Katia K. Mattis, Nicole A. J. Krentz, Christoph Metzendorf, Fernando Abaitua, Aliya F. Spigelman, Han Sun, Jennifer M. Ikle, Swaraj Thaman, Antje K. Rottner, Austin Bautista, Eugenia Mazzaferro, Marta Perez-Alcantara, Jocelyn E. Manning Fox, Jason M. Torres, Agata Wesolowska-Andersen, Grace Z. Yu, Anubha Mahajan, Anders Larsson, Patrick E. MacDonald, Benjamin Davies, Marcel den Hoed, Anna L. Gloyn
Publikováno v:
Diabetologia. 66:674-694
Aims/hypothesis Genome-wide studies have uncovered multiple independent signals at the RREB1 locus associated with altered type 2 diabetes risk and related glycaemic traits. However, little is known about the function of the zinc finger transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84fa56621fef9812409ed7ea80259057
https://doi.org/10.1007/s00125-022-05856-6
https://doi.org/10.1007/s00125-022-05856-6
Autor:
Katia K Mattis, Nicole AJ Krentz, Christoph Metzendorf, Fernando Abaitua, Aliya F Spigelman, Han Sun, Antje K Rottner, Austin Bautista, Eugenia Mazzaferro, Marta Perez-Alcantara, Jocelyn E Manning Fox, Jason M Torres, Agata Weslowska-Andersen, Grace Z Yu, Anubha Mahajan, Anders Larsson, Patrick E MacDonald, Benjamin Davies, Marcel den Hoed, Anna L Gloyn
Aims/hypothesisGenome-wide studies have uncovered multiple independent signals at the RREB1 locus associated with altered type 2 diabetes risk and related glycemic traits. However, little is known about the function of the zinc finger transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b14dd72cf45b81955edfc3f7821ec3
https://doi.org/10.1101/2022.06.04.494826
https://doi.org/10.1101/2022.06.04.494826
Autor:
Katia K. Mattis, Anna L. Gloyn
Publikováno v:
Journal of molecular biology. 432(5)
Genome-wide association studies (GWAS) have identified over 400 signals robustly associated with risk for type 2 diabetes (T2D). At the vast majority of these loci, the lead single nucleotide polymorphisms (SNPs) reside in noncoding regions of the ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d25258180bf72d5c92a77473d1f7a69
https://pubmed.ncbi.nlm.nih.gov/31945378
https://pubmed.ncbi.nlm.nih.gov/31945378
Autor:
Agata Wesolowska-Andersen, Fernando Abaitua, Katia K. Mattis, Marta Perez-Alcantara, Anna L. Gloyn, Antje Grotz, Mark I. McCarthy, Benjamin Davies, Anubha Mahajan
Publikováno v:
Diabetes. 68
Genome-wide association studies have identified multiple independent signals for type 2 diabetes risk at the RREB1 locus. Coding variant fine-mapping (D1171N, rs9379084) indicated RREB1 as the effector transcript. To investigate the role of this tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcd41e322f28e317c9557c46d0851e34
https://doi.org/10.2337/db19-3-lb
https://doi.org/10.2337/db19-3-lb
Autor:
Susan M. O’Connell, Gregor Sachse, Peter Proks, Frances M. Ashcroft, Andrew T. Hattersley, Jayne A L Houghton, Stephen Mp O’Riordan, Sian Ellard, Katia K. Mattis, Holger B. Kramer, Caroline Joyce
Publikováno v:
Clinical Case Reports
Key Clinical Message: In infants, especially with novel previously undescribed mutations of the KATP channel causing neonatal diabetes, in vitro studies can be used to both predict the response to sulphonylurea treatment and support a second trial of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6b8065c5d6ce333ad2cfa95c4ae556
http://europepmc.org/articles/PMC4614663
http://europepmc.org/articles/PMC4614663
Autor:
Frances M. Ashcroft, Ioannis Spiliotis, Anne Clark, Kenju Shimomura, Quan Zhang, P Rorsman, Fiona M. Gribble, Katia K. Mattis, William Dace, Reshma Ramracheya, Alice E. Adriaenssens, Melissa F. Brereton, Frank Reimann, Peter Proks, Michaela Iberl
Publikováno v:
Nature Communications
Diabetes is characterized by hyperglycaemia due to impaired insulin secretion and aberrant glucagon secretion resulting from changes in pancreatic islet cell function and/or mass. The extent to which hyperglycaemia per se underlies these alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dfed30a8d4cf9afd2ac78debf41233
https://doi.org/10.1038/ncomms5639
https://doi.org/10.1038/ncomms5639