Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Katia Gagne"'
Autor:
Enora Ferron, Gaëlle David, Catherine Willem, Nolwenn Legrand, Perla Salameh, Laetitia Anquetil, Alexandre Walencik, Ketevan Gendzekhadze, Katia Gagne, Christelle Retière
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionPolymorphisms in the KIR and HLA genes contribute to the diversity of the NK cell repertoire. Extrinsic factors also play a role in modifying this repertoire. The best example is cytomegalovirus, which promotes the expansion of memory-lik
Externí odkaz:
https://doaj.org/article/dda0103c54a243779d842b3b3faae82b
Autor:
Maxime Boy, Valeria Bisio, Lin-Pierre Zhao, Fabien Guidez, Bérénice Schell, Emilie Lereclus, Guylaine Henry, Juliette Villemonteix, Fernando Rodrigues-Lima, Katia Gagne, Christelle Retiere, Lise Larcher, Rathana Kim, Emmanuelle Clappier, Marie Sebert, Arsène Mekinian, Olivier Fain, Anne Caignard, Marion Espeli, Karl Balabanian, Antoine Toubert, Pierre Fenaux, Lionel Ades, Nicolas Dulphy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Myelodysplastic syndromes are characterised by clonal haematopoiesis, with the affected cells often harbouring mutations in the TET2 gene, an important regulator of DNA methylation state. Here authors show that the same mutations are also found in NK
Externí odkaz:
https://doaj.org/article/e6f10687f44445c184e49bfa3bcfcf30
Autor:
Gaëlle David, Catherine Willem, Nolwenn Legrand, Zakia Djaoud, Pierre Mérieau, Alexandre Walencik, Thierry Guillaume, Katia Gagne, Patrice Chevallier, Christelle Retière
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract KIR are mainly expressed on NK cells and to a lesser extent on T lymphocytes. Although the KIR NK cell repertoire was well explored in haploidentical Hematopoietic Stem Cell Transplantation (HSCT), KIR T cell compartment remains to be invest
Externí odkaz:
https://doaj.org/article/6d647b4ddb4e4b30bc075d7c4404c291
Autor:
Nolwenn Legrand, Perla Salameh, Maxime Jullien, Patrice Chevallier, Enora Ferron, Gaelle David, Marie-Claire Devilder, Catherine Willem, Ketevan Gendzekhadze, Peter Parham, Christelle Retière, Katia Gagne
Publikováno v:
Cancers, Vol 15, Iss 10, p 2754 (2023)
KIR3DL1 alleles are expressed at different levels on the natural killer (NK) cell surface. In particular, the non-expressed KIR3DL1*004 allele appears to be common in Caucasian populations. However, the overall distribution of non-expressed KIR3DL1 a
Externí odkaz:
https://doaj.org/article/810cea8da67d4a3a84dd6fcdd5f1fe38
Autor:
Dhon Roméo Makanga, Maxime Jullien, Gaëlle David, Nolwenn Legrand, Catherine Willem, Léa Dubreuil, Alexandre Walencik, Cyrille Touzeau, Thomas Gastinne, Benoit Tessoulin, Steven Le Gouill, Béatrice Mahé, Katia Gagne, Patrice Chevallier, Béatrice Clemenceau, Christelle Retière
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The antibody-dependent cellular cytotoxicity (ADCC) effector function of natural killer (NK) cells is one of the known mechanisms of action for rituximab-based anti-cancer immunotherapy. Inhibition of the ADCC function of NK cells through interaction
Externí odkaz:
https://doaj.org/article/80b7730a1d514071be366fcf76ad7c65
Publikováno v:
Cancers, Vol 13, Iss 15, p 3767 (2021)
Since the mid-1990s, the biology and functions of natural killer (NK) cells have been deeply investigated in healthy individuals and in people with diseases. These effector cells play a particularly crucial role after allogeneic hematopoietic stem-ce
Externí odkaz:
https://doaj.org/article/8cb97a98b1b04463a52302084ac14e54
Autor:
Léa Dubreuil, Bercelin Maniangou, Patrice Chevallier, Agnès Quéméner, Nolwenn Legrand, Marie C. Béné, Catherine Willem, Gaëlle David, Mehdi Alizadeh, Dhon Roméo Makanga, Anne Cesbron, Ketevan Gendzekhadze, Katia Gagne, Christelle Retière
Publikováno v:
Cancers, Vol 12, Iss 12, p 3595 (2020)
We have recently shown a broad disparity of Natural Killer (NK) cell responses against leukemia highlighting good and bad responders resting on the Killer cell Immunoglobulin-like Receptors (KIR) and HLA genetics. In this study, we deeply studied KIR
Externí odkaz:
https://doaj.org/article/9a1b873b26d542f3b3f3630df5710958
Autor:
Dhon Roméo Makanga, Francesca Da Rin de Lorenzo, Gaëlle David, Catherine Willem, Léa Dubreuil, Nolwenn Legrand, Thierry Guillaume, Pierre Peterlin, Amandine Lebourgeois, Marie Christine Béné, Alice Garnier, Patrice Chevallier, Ketevan Gendzekhadze, Anne Cesbron, Katia Gagne, Béatrice Clemenceau, Christelle Retière
Publikováno v:
Cancers, Vol 12, Iss 7, p 1927 (2020)
Natural killer (NK) cells are key cytotoxic effectors against malignant cells. Polygenic and polymorphic Killer cell Immunoglobulin-like Receptor (KIR) and HLA genes participate in the structural and functional formation of the NK cell repertoire. In
Externí odkaz:
https://doaj.org/article/9be1864094e8485a99503e9ab7abadb5
Autor:
Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Jean-Paul Soulillou, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Externí odkaz:
https://doaj.org/article/558d0cdccd1644dd9b63ceb1d383828a
Autor:
Emilie Dugast, Gaëlle David, Romain Oger, Richard Danger, Jean-Paul Judor, Katia Gagne, Mélanie Chesneau, Nicolas Degauque, Jean-Paul Soulillou, Pascale Paul, Christophe Picard, Pierrick Guerif, Sophie Conchon, Magali Giral, Nadine Gervois, Christelle Retière, Sophie Brouard
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The role of natural killer (NK) cells in organ transplantation is controversial. This study aims to decipher their role in kidney transplant tolerance in humans. Previous studies highlighted several modulated genes involved in NK cell biology in bloo
Externí odkaz:
https://doaj.org/article/d9c8d9fa0f8042abb15d408f7485a62a