Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Katia D'Ambrosio"'
Autor:
Emma Langella, Anna Di Fiore, Vincenzo Alterio, Simona Maria Monti, Giuseppina De Simone, Katia D’Ambrosio
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 12045 (2022)
Carbonic anhydrases (CAs) are ubiquitous enzymes that catalyze the reversible carbon dioxide hydration reaction. Among the eight different CA classes existing in nature, the α-class is the largest one being present in animals, bacteria, protozoa, fu
Externí odkaz:
https://doaj.org/article/58af4ea79dbb4331be0929e3bc2f02ca
Autor:
Emma Langella, Vincenzo Alterio, Katia D’Ambrosio, Roberta Cadoni, Jean-Yves Winum, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone, Anna Di Fiore
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 1498-1505 (2019)
Recent studies identified the benzoxaborole moiety as a new zinc-binding group able to interact with carbonic anhydrase (CA) active site. Here, we report a structural analysis of benzoxaboroles containing urea/thiourea groups, showing that these mole
Externí odkaz:
https://doaj.org/article/83251cf196c344de85ae41f9443a013d
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 7, Pp 15456-15480 (2015)
Carbonic anhydrases are ubiquitous metallo-enzymes which catalyze the reversible hydration of carbon dioxide in bicarbonate ions and protons. Recent years have seen an increasing interest in the utilization of these enzymes in CO2 capture and storage
Externí odkaz:
https://doaj.org/article/2a20c56560de4c9d94a7fcea359b0853
Autor:
Martina Buonanno, Anna Di Fiore, Emma Langella, Katia D’Ambrosio, Claudiu T. Supuran, Simona Maria Monti, Giuseppina De Simone
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 6, p 1571 (2018)
Although important progress has been achieved in understanding the catalytic mechanism of Carbonic Anhydrases, a detailed picture of all factors influencing the catalytic efficiency of the various human isoforms is still missing. In this paper we rep
Externí odkaz:
https://doaj.org/article/bc87b64f339b47629eb8133b1a7a861a
Autor:
Fabiano Cimmino, Lidia Petrella, Gina Cavaliere, Katia Ambrosio, Giovanna Trinchese, Vincenzo Monda, Margherita D’Angelo, Cristiana Di Giacomo, Alessandro Sacconi, Giovanni Messina, Maria Pina Mollica, Angela Catapano
Publikováno v:
Journal of Functional Morphology and Kinesiology, Vol 8, Iss 3, p 107 (2023)
The correct assessment of body composition is essential for an accurate diagnostic evaluation of nutritional status. The body mass index (BMI) is the most widely adopted indicator for evaluating undernutrition, overweight, and obesity, but it is unsu
Externí odkaz:
https://doaj.org/article/dc8bc4aa0db7456081224c521e500f40
Autor:
Katia, D'Ambrosio, Simone, Carradori, Stefania, Cesa, Andrea, Angeli, Simona M, Monti, Claudiu T, Supuran, Giuseppina, De Simone
Publikováno v:
Chemical communications (Cambridge, England). 56(85)
To date, catechols have been only poorly investigated as carbonic anhydrase (CA) inhibitors. Here we report the first structural information on the CA inhibition mechanism of these molecules, showing that they adopt a peculiar binding mode to the enz
Autor:
Katia D'Ambrosio, Fabrizio Carta, Simona Maria Monti, Andrea Angeli, Elena Lucarini, Giuseppina De Simone, Ozlem Akgul, Lorenzo Di Cesare Mannelli, Claudiu T. Supuran, Martina Buonanno, Carla Ghelardini
Publikováno v:
European Journal of Medicinal Chemistry. 227:113956
We report a series of compounds 1-17 derived from the antiepileptic drug Sulthiame (SLT) from which both the benzenesulfonamide and the sultam moiety were retained. All compounds were tested in vitro for their inhibition activity against the human (h
Autor:
Katia D'Ambrosio, Giuseppina De Simone
Publikováno v:
Current medicinal chemistry. 25(39)
Autor:
Vincenzo Alterio, Andrea Angeli, Ashok Aspatwar, Joelle Ayoub, Mihail Barboiu, Harlan Barker, Emanuela Berrino, Patrizio Blandina, Alessandro Bonardi, Murat Bozdag, Silvia Bua, Martina Buonanno, Clemente Capasso, Simone Carradori, Fabrizio Carta, Katia D'Ambrosio, Giuseppina De Simone, Anna Di Fiore, William A. Donald, Reza Zolfaghari Emameh, Davide Esposito, Marta Ferraroni, Paola Gratteri, Paolo Guglielmi, Marc A. Ilies, Emma Langella, Laura Lucarini, Emanuela Masini, Robert McKenna, Simona Maria Monti, Akilah B. Murray, Alessio Nocentini, Seppo Parkkila, Andrea Scozzafava, Silvia Sgambellone, Claudiu T. Supuran, Muhammet Tanc, Martti Tolvanen, Daniela Vullo, Jean-Yves Winum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f517e5aa3672a2b5ac8b0f0a898b1e8
https://doi.org/10.1016/b978-0-12-816476-1.01002-9
https://doi.org/10.1016/b978-0-12-816476-1.01002-9
η- and θ-carbonic anhydrases (CAs) are the last two classes of the CA enzyme family to be discovered in Plasmodium species and the marine diatom Phaeodactylum tricornutum, respectively. For both classes only one representative member has been chara
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd893cbe271bfb377d13a40673de46f1
https://doi.org/10.1016/b978-0-12-816476-1.00007-1
https://doi.org/10.1016/b978-0-12-816476-1.00007-1