Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Katia Carmine-Simmen"'
Autor:
Nisha Kanwar, Katia Carmine-Simmen, Ranju Nair, Chunjie Wang, Soode Moghadas-Jafari, Heiko Blaser, Danh Tran-Thanh, Dongyu Wang, Peiqi Wang, Jenny Wang, Adrian Pasculescu, Alessandro Datti, Tak Mak, John D. Lewis, Susan J. Done
Publikováno v:
EBioMedicine, Vol 52, Iss , Pp - (2020)
Background: Previously, we found that amplification of chromosome 17q24.1-24.2 is associated with lymph node metastasis, tumour size, and lymphovascular invasion in invasive ductal carcinoma. A gene within this amplicon, CACNG4, an L-type voltage-gat
Externí odkaz:
https://doaj.org/article/bcf2fd8c92ec438eb03e56d62e88cb82
Autor:
Hon S. Leong, Amy E. Robertson, Konstantin Stoletov, Sean J. Leith, Curtis A. Chin, Andrew E. Chien, M. Nicole Hague, Amber Ablack, Katia Carmine-Simmen, Victor A. McPherson, Carl O. Postenka, Eva A. Turley, Sara A. Courtneidge, Ann F. Chambers, John D. Lewis
Publikováno v:
Cell Reports, Vol 8, Iss 5, Pp 1558-1570 (2014)
Tumor cell extravasation is a key step during cancer metastasis, yet the precise mechanisms that regulate this dynamic process are unclear. We utilized a high-resolution time-lapse intravital imaging approach to visualize the dynamics of cancer cell
Externí odkaz:
https://doaj.org/article/8c78d3b31e9a449eb0c66822ac1f735e
Autor:
Jill S. Wentzell, Bonnie J. Bolkan, Katia Carmine-Simmen, Tracy L. Swanson, Derek T. Musashe, Doris Kretzschmar
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 78-87 (2012)
The processing of Amyloid Precursor Proteins (APPs) results in several fragments, including soluble N-terminal ectodomains (sAPPs) and C-terminal intracellular domains (AICD). sAPPs have been ascribed neurotrophic or neuroprotective functions in cell
Externí odkaz:
https://doaj.org/article/33045ddec3b049e5b1df7a6bf5d889a5
Autor:
Katia Carmine-Simmen, Thomas Proctor, Jakob Tschäpe, Burkhard Poeck, Tilman Triphan, Roland Strauss, Doris Kretzschmar
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 274-281 (2009)
The accumulation of amyloid-β (Aβ) into plaques is a hallmark feature of Alzheimer's disease (AD). While amyloid precursor protein (APP)-related proteins are found in most organisms, only Aβ fragments from human APP have been shown to induce amylo
Externí odkaz:
https://doaj.org/article/400334f94c5f484e92d0c4bb4f0a6681
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135245 (2015)
Tumor neovascularization is targeted by inhibition of vascular endothelial growth factor (VEGF) or the receptor to prevent tumor growth, but drug resistance to angiogenesis inhibition limits clinical efficacy. Inhibition of the phosphoinositide 3 kin
Externí odkaz:
https://doaj.org/article/ce9bf1c10caf49408737197feea663ec
Autor:
Rony Pain, Erwan Beauchamp, Katia Carmine-Simmen, Jay Gamma, Rebecca Reif, Abul Azad, Allan Murray, John Lewis, Luc Berthiaume
Publikováno v:
Cancer Research. 83:3620-3620
Myristoylation is the modification of proteins by the 14-carbon fatty acid myristate. In humans, two N-myristoyltransferases (NMT1 and NMT2) catalyze myristate transfer onto >200 proteins to regulate membrane binding and signal transduction. The pan-
Autor:
Jan Rudzinski, Natasha Govindasamy, Konstantin Stoletov, Katia Carmine-Simmen, Arun Raturi, John Lewis
Publikováno v:
Journal of Urology. 207
Autor:
Arun Raturi, Jailal Ablack, Ping Wee, Prakash Bhandari, Douglas W. Brown, Maryam Hejazi, Nichole McMullen, Liliya Grin, Hector Vega, Henry Garcia, Natasha Govindasamy, Jitendra Kumar, Paola Solis Ares, Chandra McAllister, Katia Carmine-Simmen, Perrin H. Beatty, Adam Nelson, Eric S. Pringle, Thornton Thompson, Manoj Parmar, Jennifer Gyoba, Hong Jiang, Brent Johnston, Craig McCormick, Mary Foley, Magen Ellen Francis, Brian Abel, Alyson Kelvin, Roy Duncan, John D. Lewis
Publikováno v:
SSRN Electronic Journal.
Autor:
John D. Lewis, Peiqi Wang, Soode Moghadas-Jafari, Danh Tran-Thanh, Jenny Wang, Alessandro Datti, Dong-Yu Wang, Chunjie Wang, Tak W. Mak, Susan J. Done, Adrian Pasculescu, Katia Carmine-Simmen, Ranju Nair, Nisha Kanwar, Heiko Blaser
Publikováno v:
EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)
EBioMedicine, Vol 52, Iss, Pp-(2020)
Background: Previously, we found that amplification of chromosome 17q24.1-24.2 is associated with lymph node metastasis, tumour size, and lymphovascular invasion in invasive ductal carcinoma. A gene within this amplicon, CACNG4, an L-type voltage-gat
Summary The β-amyloid precursor protein (APP) plays a central role in the etiology of Alzheimer's disease (AD). However, its normal physiological functions are still unclear. APP is cleaved by various secretases whereby sequential processing by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6fadd721795628aa597c11bbfb6ba0
https://europepmc.org/articles/PMC5840017/
https://europepmc.org/articles/PMC5840017/