Immune responses during COVID-19 breakthrough cases in vaccinated children and adolescents

Autor: Daniela Rivera-Pérez, Constanza Méndez, Benjamín Diethelm-Varela, Felipe Melo-González, Yaneisi Vázquez, Xing Meng, Qianqian Xin, Rodrigo A. Fasce, Jorge Fernández, Judith Mora, Eugenio Ramirez, Mónica L. Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Patricio Astudillo, Nicole Le Corre, Katia Abarca, Cecilia Perret, Pablo A. González, Jorge A. Soto, Susan M. Bueno, Alexis M. Kalergis

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

BackgroundVaccine effectiveness against SARS-CoV-2 infection has been somewhat limited due to the widespread dissemination of the Omicron variant, its subvariants, and the immune response dynamics of the naturally infected with the virus.MethodsTwelv

Externí odkaz: https://doaj.org/article/7c001b5b42b5457faed5b3a10f22f0e2

Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adultsResearch in context

Autor: Constanza Méndez, Hernán F. Peñaloza, Bárbara M. Schultz, Alejandro Piña-Iturbe, Mariana Ríos, Daniela Moreno-Tapia, Patricia Pereira-Sánchez, Diane Leighton, Claudia Orellana, Consuelo Covarrubias, Nicolás M.S. Gálvez, Jorge A. Soto, Luisa F. Duarte, Daniela Rivera-Pérez, Yaneisi Vázquez, Alex Cabrera, Sergio Bustos, Carolina Iturriaga, Marcela Urzua, María S. Navarrete, Álvaro Rojas, Rodrigo A. Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Mónica Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alba Grifoni, Alessandro Sette, Gang Zeng, Weining Meng, José V. González-Aramundiz, Pablo A. González, Katia Abarca, Felipe Melo-González, Susan M. Bueno, Alexis M. Kalergis, María Soledad Navarrete, Constanza Del Río, Dinely Del Pino, Natalia Aguirre, Grecia Salinas, Franco Vega, Acsa Salgado, Thomas Quinteros, Marlene Ortiz, Marcela Puente, Alma Muñoz, Patricio Astudillo, Nicole Le Corre, Marcela Potin, Juan Catalán, Melan Peralta, Consuelo Zamanillo, Nicole Keller, Rocío Fernández, Sofía Aljaro, Sofía López, José Tomás González, Tania Weil, Luz Opazo, Paula Muñoz, Inés Estay, Miguel Cantillana, Liliana Carrera, Matías Masalleras, Paula Guzmán, Francisca Aguirre, Aarón Cortés, Luis Federico Bátiz, Javiera Pérez, Karen Apablaza, Lorena Yates, María de los Ángeles Valdés, Bernardita Hurtado, Veronique Venteneul, Constanza Astorga, Paula Muñoz-Venturelli, Pablo A. Vial, Andrea Schilling, Daniela Pavez, Inia Pérez, Amy Riviotta, Francisca González, Francisca Urrutia, Alejandra Del Río, Claudia Asenjo, Bárbara Vargas, Francisca Castro, Alejandra Acuña, Javiera Guzmán, Camila Astudillo, Carlos M. Pérez, Pilar Espinoza, Andrea Martínez, Marcela Arancibia, Harold Romero, Cecilia Bustamante, María Loreto Pérez, Natalia Uribe, Viviana Silva, Bernardita Morice, Marco Pérez, Marcela González, Werner Jensen, Claudia Pasten, M. Fernanda Aguilera, Nataly Martínez, Camila Molina, Sebastián Arrieta, Begoña López, Claudia Ortiz, Macarena Escobar, Camila Bustamante, Marcia Espinoza, Angela Pardo, Alison Carrasco, Miguel Montes, Macarena Saldías, Natalia Gutiérrez, Juliette Sánchez, Daniela Fuentes, Yolanda Calvo, Mariela Cepeda, Rosario Lemus, Muriel Suárez, Mercedes Armijo, Shirley Monsalves, Constance Marucich, Cecilia Cornejo, Ángela Acosta, Xaviera Prado, Francisca Yáñez, Marisol Barroeta, Claudia López, Paulina Donato, Martin Lasso, María Iturrieta, Juan Giraldo, Francisco Gutiérrez, María Acuña, Ada Cascone, Raymundo Rojas, Camila Sepúlveda, Mario Contreras, Yessica Campisto, Pablo González, Zoila Quizhpi, Mariella López, Vania Pizzeghello, Stephannie Silva

Publikováno v: EBioMedicine, Vol 91, Iss , Pp 104563- (2023)

Summary: Background: The Omicron variant has challenged the control of the COVID-19 pandemic due to its immuno-evasive properties. The administration of a booster dose of a SARS-CoV-2 vaccine showed positive effects in the immunogenicity against SARS

Externí odkaz: https://doaj.org/article/ada72f7a33e042e3b8078e201eaafcb4

Eco-epidemiology of rodent-associated trombiculid mites and infection with Orientia spp. in Southern Chile.

Autor: María Carolina Silva de la Fuente, Caricia Pérez, Constanza Martínez-Valdebenito, Ruth Pérez, Cecilia Vial, Alexandr Stekolnikov, Katia Abarca, Thomas Weitzel, Gerardo Acosta-Jamett

Publikováno v: PLoS Neglected Tropical Diseases, Vol 17, Iss 1, p e0011051 (2023)

BackgroundScrub typhus is a potentially severe infection caused by bacteria of the genus Orientia, endemic in Asia-Pacific and recently discovered in southern Chile. The presented study aimed to determine the prevalence and species richness of rodent

Externí odkaz: https://doaj.org/article/a40c9102015b4b1c8be582891975159a

Differences in the immune response elicited by two immunization schedules with an inactivated SARS-CoV-2 vaccine in a randomized phase 3 clinical trial

Autor: Nicolás MS Gálvez, Gaspar A Pacheco, Bárbara M Schultz, Felipe Melo-González, Jorge A Soto, Luisa F Duarte, Liliana A González, Daniela Rivera-Pérez, Mariana Ríos, Roslye V Berrios, Yaneisi Vázquez, Daniela Moreno-Tapia, Omar P Vallejos, Catalina A Andrade, Guillermo Hoppe-Elsholz, Carolina Iturriaga, Marcela Urzua, María S Navarrete, Álvaro Rojas, Rodrigo Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Mónica L Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alba Grifoni, Alessandro Sette, Gang Zeng, Weining Meng, CoronaVacCL03 Study Group, José V González-Aramundiz, Marina Johnson, David Goldblatt, Pablo A González, Katia Abarca, Susan M Bueno, Alexis M Kalergis

Publikováno v: eLife, Vol 11 (2022)

Background: The development of vaccines to control the coronavirus disease 2019 (COVID-19) pandemic progression is a worldwide priority. CoronaVac is an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine approved for eme

Externí odkaz: https://doaj.org/article/ac762f639ff7488791e3508152fce059

A Booster Dose of CoronaVac Increases Neutralizing Antibodies and T Cells that Recognize Delta and Omicron Variants of Concern

Autor: Bárbara M. Schultz, Felipe Melo-González, Luisa F. Duarte, Nicolás M. S. Gálvez, Gaspar A. Pacheco, Jorge A. Soto, Roslye V. Berríos-Rojas, Liliana A. González, Daniela Moreno-Tapia, Daniela Rivera-Pérez, Mariana Ríos, Yaneisi Vázquez, Guillermo Hoppe-Elsholz, Catalina A. Andrade-Parra, Omar P. Vallejos, Alejandro Piña-Iturbe, Carolina Iturriaga, Marcela Urzua, María S. Navarrete, Álvaro Rojas, Rodrigo Fasce, Jorge Fernández, Judith Mora, Eugenio Ramírez, Aracelly Gaete-Argel, Mónica L. Acevedo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Daniela Weiskopf, Alba Grifoni, Alessandro Sette, Gang Zeng, Weining Meng, José V. González-Aramundiz, Pablo A. González, Katia Abarca, Alexis M. Kalergis, Susan M. Bueno

Publikováno v: mBio, Vol 13, Iss 4 (2022)

ABSTRACT CoronaVac is an inactivated SARS-CoV-2 vaccine approved by the World Health Organization (WHO). Previous studies reported increased levels of neutralizing antibodies and specific T cells 2 and 4 weeks after two doses of CoronaVac; these leve

Externí odkaz: https://doaj.org/article/0d12c0aeee20419bb5fc3ab69b554f1b