Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kati Turkowski"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 9086 (2024)
Cancer cells can escape death and surveillance by the host immune system in various ways. Programmed cell death ligand 1 (PD-L1) is a transmembrane protein that is expressed by most cell types, including cancer cells, and can provide an inhibitory si
Externí odkaz:
https://doaj.org/article/8ef7d2cd241b45db9bb71ba5abb59579
Autor:
Andreas Weigert, Xiang Zheng, Alina Nenzel, Kati Turkowski, Stefan Günther, Elisabeth Strack, Evelyn Sirait-Fischer, Eiman Elwakeel, Ivan M. Kur, Vandana S. Nikam, Chanil Valasarajan, Hauke Winter, Alexander Wissgott, Robert Voswinkel, Friedrich Grimminger, Bernhard Brüne, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Fibrocytes are monocyte-derived cells implicated in wound healing. Here, the authors utilise single cell RNA-seq, genetic ablation and multiplexed imaging to identify a fibrocyte population in lung cancer models, and use human lung cancer coculture s
Externí odkaz:
https://doaj.org/article/a45ef476278744d49bbf2334b639d6fb
Autor:
Sebastian Marwitz, Kati Turkowski, Dörte Nitschkowski, Andreas Weigert, Julius Brandenburg, Norbert Reiling, Michael Thomas, Martin Reck, Daniel Drömann, Werner Seeger, Klaus F. Rabe, Rajkumar Savai, Torsten Goldmann
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Although immune checkpoint and targeted therapies offer remarkable benefits for lung cancer treatment, some patients do not qualify for these regimens or do not exhibit consistent benefit. Provided that lung cancer appears to be driven by transformin
Externí odkaz:
https://doaj.org/article/93cd96c94a354f28b6fc59e7f5b59442
Autor:
Kati Turkowski, Frederik Herzberg, Stefan Günther, David Brunn, Andreas Weigert, Michael Meister, Thomas Muley, Mark Kriegsmann, Marc A. Schneider, Hauke Winter, Michael Thomas, Friedrich Grimminger, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Publikováno v:
Cells, Vol 9, Iss 8, p 1755 (2020)
Investigation of the molecular dynamics in lung cancer is crucial for the development of new treatment strategies. Fibroblast growth factor (FGF) 14 belongs to the FGF family, which might play a crucial role in cancer progression. We analyzed lung ad
Externí odkaz:
https://doaj.org/article/820ba1518e5f479fa69b006d642900aa
Autor:
Xiang Zheng, Poonam Sarode, Andreas Weigert, Kati Turkowski, Prakash Chelladurai, Stefan Günther, Carsten Kuenne, Hauke Winter, Albrecht Stenzinger, Simone Reu, Friedrich Grimminger, Thorsten Stiewe, Werner Seeger, Soni Savai. Pullamsetti, Rajkumar Savai
Publikováno v:
Cancer Research.
Tumor-associated macrophages (TAMs), including anti-tumor M1-like TAMs and pro-tumor M2-like TAMs, are transcriptionally dynamic innate immune cells with diverse roles in lung cancer development. Epigenetic regulators are key in controlling macrophag
Autor:
Güliz Acker, Peter Vajkoczy, Ruth M. Urbantat, Josefine Radke, Ulf C. Schneider, Susan Brandenburg, Irina Kremenetskaia, Kati Turkowski, Anne Blank
Publikováno v:
The Journal of Pathology. 253:160-173
Myeloid cells are an inherent part of the microenvironment of glioblastoma multiforme (GBM). There is growing evidence for their participation in mechanisms of tumor escape, especially in the development of resistance following initially promising an
Autor:
Andreas Weigert, Xiang Zheng, Alina Nenzel, Kati Turkowski, Stefan Günther, Elisabeth Strack, Evelyn Sirait-Fischer, Eiman Elwakeel, Ivan M. Kur, Vandana S. Nikam, Chanil Valasarajan, Hauke Winter, Alexander Wissgott, Robert Voswinkel, Friedrich Grimminger, Bernhard Brüne, Werner Seeger, Soni Savai Pullamsetti, Rajkumar Savai
Publikováno v:
Nature communications. 13(1)
Fibrocytes are bone marrow–derived monocytic cells implicated in wound healing. Here, we identify their role in lung cancer progression/ metastasis. Selective manipulation of fibrocytes in mouse lung tumor models documents the central role of fibro
Autor:
Thomas Muley, Stefan Günther, Hauke Winter, Werner Seeger, Mark Kriegsmann, Kati Turkowski, Friedrich Grimminger, Reinhard Dammann, Soni Savai Pullamsetti, Andreas Weigert, Andreas Guenther, Rajkumar Savai, David Brunn, Georgios T. Stathopoulos, Michael Thomas
Publikováno v:
Cancers
Cancers, Vol 13, Iss 208, p 208 (2021)
Volume 13
Issue 2
Cancers 13:208 (2021)
Cancers, Vol 13, Iss 208, p 208 (2021)
Volume 13
Issue 2
Cancers 13:208 (2021)
Transcription factors can serve as links between tumor microenvironment signaling and oncogenesis. Interferon regulatory factor 9 (IRF9) is recruited and expressed upon interferon stimulation and is dependent on cofactors that exert in tumor-suppress
Autor:
Rajkumar Savai, Mark Kriegsmann, Friedrich Grimminger, Michael Meister, Michael Thomas, David Brunn, Andreas Weigert, Werner Seeger, Stefan Günther, Kati Turkowski, Thomas Muley, Frederik Herzberg, Hauke Winter, Soni Savai Pullamsetti, Marc A Schneider
Publikováno v:
Cells
Volume 9
Issue 8
Cells, Vol 9, Iss 1755, p 1755 (2020)
Volume 9
Issue 8
Cells, Vol 9, Iss 1755, p 1755 (2020)
Investigation of the molecular dynamics in lung cancer is crucial for the development of new treatment strategies. Fibroblast growth factor (FGF) 14 belongs to the FGF family, which might play a crucial role in cancer progression. We analyzed lung ad
Autor:
Angelika Gutenberg, Kati Turkowski, Etienne Ndzie Atangana, Annett Müller, Salima Magrini, Anja M. Davids, Susan Brandenburg, Claire Gehlhaar, Anna Elke, Frank L. Heppner, Ulf C. Schneider, Tobias Finger, Peter Vajkoczy, Wolfgang Brück
Publikováno v:
Acta Neuropathologica. 130:215-231
Inflammatory changes have been postulated to contribute to secondary brain injury after aneurysmal subarachnoid hemorrhage (SAH). In human specimens after SAH as well as in experimental SAH using mice, we show an intracerebral accumulation of inflamm