Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kati Pulkkinen"'
Autor:
Ulrika Norén-Nyström, Mette K. Andersen, Gisela Barbany, Vaidas Dirse, Martine Eilert-Olsen, Marie Engvall, Arja Harila-Saari, Mats Heyman, Randi Hovland, Satu Häikiö, Jón J. Jónsson, Ritva Karhu, Eigil Kjeldsen, Anna Norberg, Birgitte S. Preiss, Kati Pulkkinen, Petter Quist-Paulsen, Hannele Räsänen, Kjeld Schmiegelow, Anne Seitsonen, Helene Sjögren, Pille Tammur, Bertil Johansson
Publikováno v:
HemaSphere, Vol 7, Iss 5, p e883 (2023)
Externí odkaz:
https://doaj.org/article/951b6b369c904fbc872a2daa70a62c7f
Autor:
Anne Rokka, Anna Oksanen, Garry L. Corthals, Sanna Hämäläinen, Kati Pulkkinen, Ilkka Junttila, John J. O'Shea, Dragana Jankovic, Zsuzsanna Ortutay, Wendy T. Watford, Marko Pesu, Saara Aittomäki
Publikováno v:
The Journal of Immunology. 193:5470-5479
The proprotein convertase subtilisin/kexin enzymes proteolytically convert immature proproteins into bioactive molecules, and thereby they serve as key regulators of cellular homeostasis. The archetype proprotein convertase subtilisin/kexin, FURIN, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a246ede543697576ff180bf3b5fb8d83
https://doi.org/10.4049/jimmunol.1401629
https://doi.org/10.4049/jimmunol.1401629
Autor:
Pauli Tuoresmäki, Suvi M. Kuosmanen, Mikko Hippeläinen, Kati Pulkkinen, Anna-Liisa Levonen, Juha Hartikainen, Pasi Tavi, Virve Sihvola, Henna-Kaisa Jyrkkänen, Sami Heikkinen, Hannu Kokki, Minna U. Kaikkonen, Emilia Kansanen
Publikováno v:
Nucleic Acids Research
Phospholipids, such as 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (PAPC), are the major components of cell membranes. Their exposure to reactive oxygen species creates oxidized phospholipids, which predispose to the development of chronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c679a75917f145227a407e907e9338c
https://erepo.uef.fi/handle/123456789/5749
https://erepo.uef.fi/handle/123456789/5749
Publikováno v:
Free Radical Biology and Medicine. 51:2124-2131
Heme oxygenase 1 (HO-1) is a stress-inducible enzyme that degrades redox-active heme-producing biliverdin, carbon monoxide, and Fe(2+). It protects cells under various stress conditions and mediates anti-inflammatory and vasodilatory effects in the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aaf5ea415ac1542ae2de55ec40b83a
https://doi.org/10.1016/j.freeradbiomed.2011.09.014
https://doi.org/10.1016/j.freeradbiomed.2011.09.014
Autor:
Tarja Malm, Jari Koistinaho, Petri I. Mäkinen, Mikko P. Turunen, Kati Pulkkinen, Seppo Ylä-Herttuala, Anna-Mari Kärkkäinen, Jonna K. Koponen
Publikováno v:
The Journal of Gene Medicine. 8:433-441
Background RNA interference (RNAi) is a post-transcriptional RNA degradation process, which has become a very useful tool in gene function studies and gene therapy applications. Long-term cellular expression of small interfering RNA (siRNA) molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2036fff66e6434bfaaf1317446fc28
https://doi.org/10.1002/jgm.860
https://doi.org/10.1002/jgm.860
Autor:
Anouk Van Nuffel, Tom Taghon, Bruno Verhasselt, Inge Van de Walle, Evelien Naessens, Kevin K. Ariën, Veronique Stove, Kati Pulkkinen, Oliver T. Fackler, Jan Schmökel, Eduardo O’Neill, J. Victor Garcia, Kathleen Van Landeghem, Kalle Saksela, Hanne Vanderstraeten, Frank Kirchhoff, Michael Schindler
Publikováno v:
Retrovirology
RETROVIROLOGY
RETROVIROLOGY
Background A nef gene is present in all primate lentiviral genomes and is important for high viral loads and progression to AIDS in human or experimental macaque hosts of HIV or SIV, respectively. In these hosts, infection of the thymus results in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579b25db1ae34cc11d3337c90755a06a
http://hdl.handle.net/10138/162613
http://hdl.handle.net/10138/162613
Autor:
Jonna K. Koponen, Hanna Sallinen, Seppo Ylä-Herttuala, Maarit Anttila, Kirsi Hämäläinen, Kari Alitalo, Seppo Heinonen, Pyry I. Toivanen, Veli-Matti Kosma, Laura Tuppurainen, Emmi Kokki, Kati Pulkkinen, Tommi Heikura
Publikováno v:
Human gene therapy. Clinical development. 24(1)
Antiangiogenic and antilymphangiogenic gene therapy with soluble vascular endothelial growth factor receptor-2 (VEGFR-2) and soluble VEGFR-3 in combination with chemotherapy is a potential new treatment for ovarian carcinoma. We evaluated the safety,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2588fb98d82a8e284785266496cecfc4
https://pubmed.ncbi.nlm.nih.gov/23692381
https://pubmed.ncbi.nlm.nih.gov/23692381
Identification of proprotein convertase substrates using genome-wide expression correlation analysis
Autor:
Vesa P. Hytönen, Kalle Ojala, Marko Pesu, Timo Kauppila, Sampo Kukkurainen, Hannu Turpeinen, Kati Pulkkinen
Publikováno v:
BMC Genomics, Vol 12, Iss 1, p 618 (2011)
BMC Genomics
BMC Genomics
Background Subtilisin/kexin-like proprotein convertase (PCSK) enzymes have important regulatory function in a wide variety of biological processes. PCSKs proteolytically process at a target sequence that contains basic amino acids arginine and lysine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fc8fdea723dd8e1ac423eee70f23c6
http://hdl.handle.net/10138/163487
http://hdl.handle.net/10138/163487
Autor:
Kalle Saksela, Kati Pulkkinen, Anke Specht, Devi Rajan, Carolin Ritter, Michael Schindler, Frank Kirchhoff
Publikováno v:
Journal of virology. 81(23)
Interaction of the human immunodeficiency virus type 1 (HIV-1) Nef protein with p21-activated kinase 2 (PAK2) has been proposed to play a role in T-cell activation, viral replication, apoptosis, and progression to AIDS. However, these hypotheses were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77e35577b1805ce1512220bfffdce65
https://pubmed.ncbi.nlm.nih.gov/17881449
https://pubmed.ncbi.nlm.nih.gov/17881449
Publikováno v:
Journal of virology. 78(23)
We have previously reported that Nef specifically interacts with a small but highly active subpopulation of p21-activated kinase 2 (PAK2). Here we show that this is due to a transient association of Nef with a PAK2 activation complex within a deterge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445b3ef4cff943454f73c51415bf54b2
https://pubmed.ncbi.nlm.nih.gov/15542629
https://pubmed.ncbi.nlm.nih.gov/15542629