Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kathy Yuen Yee, Chan"'
Autor:
Chi Zhang, Kathy Yuen Yee Chan, Wing Hei Ng, John Tak Kit Cheung, Qiwei Sun, Han Wang, Po Yee Chung, Frankie Wai Tsoi Cheng, Alex Wing Kwan Leung, Xiao-Bing Zhang, Po Yi Lee, Siu Ping Fok, Guanglan Lin, Ellen Ngar Yun Poon, Jian-Hua Feng, Yan-Lai Tang, Xue-Qun Luo, Li-Bin Huang, Wei Kang, Patrick Ming Kuen Tang, Junbin Huang, Chun Chen, Junchao Dong, Ester Mejstrikova, Jiaoyang Cai, Yu Liu, Shuhong Shen, Jun J Yang, Patrick Man Pan Yuen, Chi Kong Li, Kam Tong Leung
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Resistance to glucocorticoids (GCs), the common agents for remission induction in pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL), poses a significant therapeutic hurdle. Therefore, dissecting the mechanisms shaping GC resistance co
Externí odkaz:
https://doaj.org/article/b91b2983d67042199d70adb7860fbe66
Autor:
Yu Zheng Wu, Kathy Yuen Yee Chan, Kam Tong Leung, Hugh Simon Lam, Yuk Him Tam, Kim Hung Lee, Karen Li, Pak Cheung Ng
Publikováno v:
FEBS Open Bio, Vol 11, Iss 7, Pp 1907-1920 (2021)
We previously demonstrated that microRNA(miR)‐223 is overexpressed in intestinal tissue of infants with necrotizing enterocolitis (NEC). The objective of the current study was to identify the target gene of miR‐223 and to investigate the role of
Externí odkaz:
https://doaj.org/article/612062400a474f73a74c33e2349f1ad8
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Supplementary Data from Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340814653f430c54d027ddfe44a87c37
https://doi.org/10.1158/2643-3230.22545317.v1
https://doi.org/10.1158/2643-3230.22545317.v1
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41072df45b1d12a7e0dd4c70d3befc4e
https://doi.org/10.1158/2643-3230.c.6550904
https://doi.org/10.1158/2643-3230.c.6550904
Autor:
Kam Tong Leung, Alex Wing Kwan Leung, Chi-kong Li, Patrick Man Pan Yuen, Chun Chen, Junbin Huang, Qi Zhao, Ellen Ngar Yun Poon, Raymond S.M. Wong, Wayne Yuk Wai Lee, Ka-Fai To, Wei Kang, Patrick Ming-Kuen Tang, Wing Hei Ng, John Tak Kit Cheung, Yaqun Xu, Chi Zhang, Qiwei Sun, Yuet Ping Yuen, Chi Chiu So, Xiao-Bing Zhang, Tao Zhang, Chi Chiu Wang, Anskar Y.H. Leung, Wing Hang Leung, Alan K.S. Chiang, Shau Yin Ha, Tin Wai Chow, Grace Kee See Lam, Frankie Wai Tsoi Cheng, Po Yi Lee, Margaret H.L. Ng, Chi Keung Cheng, Kathy Yuen Yee Chan, Han Wang
Supplementary Figure from Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242d586dd08c36ec116ff3489f689f1d
https://doi.org/10.1158/2643-3230.22545314
https://doi.org/10.1158/2643-3230.22545314
Autor:
Chi Kong Li, Liz Y P Yuen, Alex Wing Kwan Leung, Terry T W Chow, Grace K S Lam, Paroni O L Fan, Takaya Moriyama, Kathy Yuen Yee Chan, Frankie W T Cheng, Kam Tong Leung, Jun J. Yang
Publikováno v:
Pediatric Hematology and Oncology. 39:254-266
Inter-individual variance in 6-mercaptopurine (6-MP) dose intensity is common in patients with acute lymphoblastic leukemia (ALL). We aimed to evaluate the association of common variants of ABCC4, ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01183c7c1107df5e0a748d7ae0eadffc
https://doi.org/10.1080/08880018.2021.1973628
https://doi.org/10.1080/08880018.2021.1973628
Autor:
Kathy Yuen Yee Chan, Yuk Him Tam, Yu Zheng Wu, Karen Li, Kim Hung Lee, Kam Tong Leung, Pak Cheung Ng, Hugh Simon Lam
Publikováno v:
FEBS Open Bio
FEBS Open Bio, Vol 11, Iss 7, Pp 1907-1920 (2021)
FEBS Open Bio, Vol 11, Iss 7, Pp 1907-1920 (2021)
We previously demonstrated that microRNA(miR)‐223 is overexpressed in intestinal tissue of infants with necrotizing enterocolitis (NEC). The objective of the current study was to identify the target gene of miR‐223 and to investigate the role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dac55ad5ede2f6fea73e94e385a1706
https://doi.org/10.1002/2211-5463.13164
https://doi.org/10.1002/2211-5463.13164
Autor:
Kathy Yuen Yee Chan, Po Yee Chung, Chi Zhang, Ellen Ngar Yun Poon, Alex Wing Kwan Leung, Kam Tong Leung
Publikováno v:
Journal of leukocyte biologyREFERENCES. 112(4)
G-protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors. They are involved in almost every physiologic process and consequently have a pivotal role in an extensive number of pathologies, including genetic, neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7868ef468cc2f793f7feac32121b63cf
https://pubmed.ncbi.nlm.nih.gov/35694792
https://pubmed.ncbi.nlm.nih.gov/35694792
Autor:
Han Wang, Kathy Yuen Yee Chan, Chi Keung Cheng, Margaret H.L. Ng, Po Yi Lee, Frankie Wai Tsoi Cheng, Grace Kee See Lam, Tin Wai Chow, Shau Yin Ha, Alan K.S. Chiang, Wing Hang Leung, Anskar Y.H. Leung, Chi Chiu Wang, Tao Zhang, Xiao-Bing Zhang, Chi Chiu So, Yuet Ping Yuen, Qiwei Sun, Chi Zhang, Yaqun Xu, John Tak Kit Cheung, Wing Hei Ng, Patrick Ming-Kuen Tang, Wei Kang, Ka-Fai To, Wayne Yuk Wai Lee, Raymond S.M. Wong, Ellen Ngar Yun Poon, Qi Zhao, Junbin Huang, Chun Chen, Patrick Man Pan Yuen, Chi-kong Li, Alex Wing Kwan Leung, Kam Tong Leung
Publikováno v:
Blood cancer discovery. 3(6)
Despite the expanding portfolio of targeted therapies for adults with acute myeloid leukemia (AML), direct implementation in children is challenging due to inherent differences in underlying genetics. Here we established the pharmacologic profile of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca555489fe5f18c2d08b830dac9f9f2
https://pubmed.ncbi.nlm.nih.gov/35960210
https://pubmed.ncbi.nlm.nih.gov/35960210
Autor:
Kin Pong Tao, Marc KC Chong, Kathy Yuen Yee CHAN, Jason Chun Sang PUN, Joseph Gar Shun TSUN, Samuel Man Wai CHOW, Calvin S.H. Ng, Maggie H. Wang, Paul K.S. Chan, Albert Martin Man Chim LI, Renee Wan Yi Chan
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2c6481da41121181da966a71710464c
https://doi.org/10.2139/ssrn.4002395
https://doi.org/10.2139/ssrn.4002395