Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kathy Vernovsky"'
Autor:
Dora Dias-Santagata, Quynh Lam, Kathy Vernovsky, Natalie Vena, Jochen K Lennerz, Darrell R Borger, Tracy T Batchelor, Keith L Ligon, A John Iafrate, Azra H Ligon, David N Louis, Sandro Santagata
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17948 (2011)
Pleomorphic xanthoastrocytoma (PXA) is low-grade glial neoplasm principally affecting children and young adults. Approximately 40% of PXA are reported to recur within 10 years of primary resection. Upon recurrence, patients receive radiation therapy
Externí odkaz:
https://doaj.org/article/b7e7b10665f146e4abe37187449a9a7b
Autor:
Thomas J. Lynch, Georgiana Kuhlmann, Susan L. Boisvert, Leif W. Ellisen, Lecia V. Sequist, Dora Dias-Santagata, Daniel A. Haber, Jeffrey Settleman, Sara Akhavanfard, Kathy Vernovsky, Ultan McDermott, Jeffrey W. Clark, Hannah Stubbs, David N. Louis, Eunice L. Kwak, Serena S. David, Jeffrey A. Engelman, Darrell R. Borger, A. John Iafrate, Steven J. Isakoff
Publikováno v:
EMBO Molecular Medicine. 2:146-158
Targeted cancer therapy requires the rapid and accurate identification of genetic abnormalities predictive of therapeutic response. We sought to develop a high-throughput genotyping platform that would allow prospective patient selection to the best
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7be8af29e41171875472d1af5b19cd99
https://doi.org/10.1002/emmm.201000070
https://doi.org/10.1002/emmm.201000070
Autor:
Julie M. Batten, Kathy Vernovsky, David G. Forcione, Brenda Sweeney, Ronald Arpin, Darrell R. Borger, Dora Dias-Santagata, Thomas O. McDonald, Long P. Le, A. John Iafrate, Jonathan C. Dudley, Zongli Zheng, William R. Brugge, Martha B. Pitman
Publikováno v:
The Journal of molecular diagnostics : JMD. 18(1)
Cytological evaluation of pancreatic or biliary duct brushings is a specific, but insensitive, test for malignancy. We compared adjunctive molecular testing with next-generation sequencing (NGS) relative to fluorescence in situ hybridization (FISH) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::801a8285da5bcf53b366d95078fe5194
https://pubmed.ncbi.nlm.nih.gov/26596524
https://pubmed.ncbi.nlm.nih.gov/26596524
Autor:
Ponzy Lu, Bao T. Do, David Jordan, Kathy Vernovsky, Vikram Pattanayak, Alan M. Gewirtz, Lida K. Gifford
Publikováno v:
Analytical Biochemistry. 347:77-88
The design of oligonucleotides for gene silencing requires a rational method for identifying hybridization-accessible sequences within the target RNA. To this end, we have developed stem-loop self-quenching reporter molecules (SQRMs) as probes for su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdd59de7dc518e153fa306187d9f7fe
https://doi.org/10.1016/j.ab.2005.08.030
https://doi.org/10.1016/j.ab.2005.08.030
Autor:
A. John Iafrate, Dora Dias-Santagata, Panos Fidias, Sara Akhavanfard, Jeffrey A. Engelman, Mari Mino-Kenudson, John C. Wain, Alexa B. Turke, Belinda A. Waltman, Arjola K. Cosper, Michael Lanuti, Eugene J. Mark, Lecia V. Sequist, Alice T. Shaw, Thomas J. Lynch, Kristin Bergethon, Kathy Vernovsky, Scott N. Gettinger, Subba R. Digumarthy, James G. Christensen, Rebecca S. Heist, Jennifer S. Temel
Publikováno v:
Science Translational Medicine. 3
Lung cancers harboring mutations in the epidermal growth factor receptor (EGFR) respond to EGFR tyrosine kinase inhibitors, but drug resistance invariably emerges. To elucidate mechanisms of acquired drug resistance, we performed systematic genetic a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f742435951f0d9a7a8a6ebea8396ea3
https://doi.org/10.1126/scitranslmed.3002003
https://doi.org/10.1126/scitranslmed.3002003
Autor:
Sandro Santagata, Jochen K. Lennerz, A. John Iafrate, Kathy Vernovsky, David N. Louis, Natalie Vena, Darrell R. Borger, Dora Dias-Santagata, Azra H. Ligon, Tracy T. Batchelor, Keith L. Ligon, Quynh Lam
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17948 (2011)
PLoS ONE
PLoS ONE
Pleomorphic xanthoastrocytoma (PXA) is low-grade glial neoplasm principally affecting children and young adults. Approximately 40% of PXA are reported to recur within 10 years of primary resection. Upon recurrence, patients receive radiation therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b28beb59f39c9c927fa4e35961179188
http://europepmc.org/articles/PMC3066220?pdf=render
http://europepmc.org/articles/PMC3066220?pdf=render
Autor:
Lesbeth C. Rodriguez, Kathy Vernovsky, Joanna B. Opalinska, Ponzy Lu, Bao T. Do, Anna Kalota, Paul Greenham, David Jordan, Lida K. Gifford, Vikram Pattanayak, Alan M. Gewirtz, Michelle Robbins
Publikováno v:
Nucleic Acids Research
We describe a physical mRNA mapping strategy employing fluorescent self-quenching reporter molecules (SQRMs) that facilitates the identification of mRNA sequence accessible for hybridization with antisense nucleic acids in vitro and in vivo, real tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ebc484212b809067bfba0c9c8f22aff
https://doi.org/10.1093/nar/gni024
https://doi.org/10.1093/nar/gni024