Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kathy N. Tomkinson"'
Autor:
Tara K. Crawford, Edward R. Lavallie, Tracy Hebert, Elisabeth A. Morris, Christopher John Corcoran, Mackie Stewart Andrews, Thomas McDonagh, Weilan Zeng, Priya S. Chockalingam, Kathy N. Tomkinson, Lisa A. Collins-Racie, Carl R. Flannery
Publikováno v:
The Journal of biological chemistry. 277(45)
ADAMTS-4, also referred to as aggrecanase-1, is a glutamyl endopeptidase capable of generating catabolic fragments of aggrecan analogous to those released from articular cartilage during degenerative joint diseases such as osteoarthritis. Efficient a
Autor:
Kathy N. Tomkinson, Thomas McDonagh, Edward R. Lavallie, Amanda J. Fosang, John D. Sandy, Jennifer Westling, Vivian P. Thompson, Lisa A. Collins-Racie, Elisabeth A. Morris, Tracy Hebert
Publikováno v:
The Journal of biological chemistry. 277(18)
Two major proteolytic cleavages, one at NITEGE(373)/A(374)RGSVI and the other at VDIPEN(341)/F(342)FGVGG, have been shown to occur in vivo within the interglobular domain of aggrecan. The Glu(373)-Ala(374) site is cleaved in vitro by aggrecanase-1 (A
Autor:
Zimmers, Teresa A., Davies, Monique V., Koniaris, Leonidas G., Haynes, Paul, Esquela, Aurora F., Tomkinson, Kathy N., McPherron, Alexandra C., Wolfman, Neil M., Se-Jin Lee
Publikováno v:
Science. 5/24/2002, Vol. 296 Issue 5572, p1486-1488. 3p. 1 Color Photograph, 4 Graphs.
Autor:
Tries, R. Scott, Chen, Tom, Da Vies, Monique V., Tomkinson, Kathy N., Pearson, Adele A., Shakey, Quazi A., Wolfman, Neil M.
Publikováno v:
Growth Factors; 2001, Vol. 18 Issue 4, p251-259, 9p